Active vibration control of a fluid loaded cylinder using inertial and reactive actuators. The active control technology outlined in this proposal presents a practical solution for low frequency noise problems associated with a submarine. The successful outcomes will be directly applicable to the Collins Class submarine, and thereby will greatly benefit Australia's naval defence industry. The active control transducer technology developed in this project will be patented, and has the potential t ....Active vibration control of a fluid loaded cylinder using inertial and reactive actuators. The active control technology outlined in this proposal presents a practical solution for low frequency noise problems associated with a submarine. The successful outcomes will be directly applicable to the Collins Class submarine, and thereby will greatly benefit Australia's naval defence industry. The active control transducer technology developed in this project will be patented, and has the potential to result in great commercial value for Australia. This project will contribute significantly to Australian research capacity in cutting-edge technologies in active vibration control. The collaboration between UNSW and the Maritime Platforms Division of DSTO will promote technology transfer and enhance Defence research expertise.Read moreRead less
Small Scale Turbulence. The thrust of the project is to gain a fundamental understanding of turbulence, which is the usual state of fluid motion. The focus will be principally on the smallest length scales of turbulence because of the potential that exists for developing a theoretical framework which can predict the behaviour of these scales accurately. Important insight will be gained into the manner in which temperature is mixed and convected by a turbulent flow.
In situ neutron diffraction mapping of tri-axial stress distributions in particulate systems. Compacting powders, which are critical in industries such as metal, advanced ceramic and pharmiceutical manufacturing, will be studied in real time using advanced neutron diffraction techniques. This will allow the three-dimensional mapping of stresses and strains within small volumes of the powder deep inside realistic compaction equipment.
Bidirectional Evolutionary Structural Optimization for Transient Problems. Aims: This proposal aims to expand the bidirectional evolutionary structural optimisation (BESO) method for transient mechanical, multiphysical and robotic problems.
Significance: The study will develop new BESO transient algorithms by integrating time-dependent analysis and stepwise design sensitivity in multicriteria and multidisciplinary optimisation.
Expected outcomes: The project will largely broaden the algorithmi ....Bidirectional Evolutionary Structural Optimization for Transient Problems. Aims: This proposal aims to expand the bidirectional evolutionary structural optimisation (BESO) method for transient mechanical, multiphysical and robotic problems.
Significance: The study will develop new BESO transient algorithms by integrating time-dependent analysis and stepwise design sensitivity in multicriteria and multidisciplinary optimisation.
Expected outcomes: The project will largely broaden the algorithmic scope of BESO and enables it to solve more extensive real-life problems with time-varying nature.
Benefits include a new BESO design framework and computer program, as well as a series of novel designs, potentially being implemented for aerospace, automotive, biomedical, mechanical, civil and mechatronic applications.Read moreRead less
THE EFFECTS OF TRANSCRANIAL MAGNETIC STIMULATION (TMS) ON RAT MODELS OF DEPRESSION
Funder
National Health and Medical Research Council
Funding Amount
$204,274.00
Summary
Repetitive Transcranial Magnetic Stimulation (rTMS) is the direct stimulation of the brain by using high field magnetic pulses. It is a new technique that has been demonstrated to have some potential as a treatment of depressive illness and possibly other neuropsychiatric disorders. At this early stage of its investigation, the parameters of stimulation that are most likely to be therapeutic, and its mechanisms of action, are not known. Published studies vary in the frequency, duration and exten ....Repetitive Transcranial Magnetic Stimulation (rTMS) is the direct stimulation of the brain by using high field magnetic pulses. It is a new technique that has been demonstrated to have some potential as a treatment of depressive illness and possibly other neuropsychiatric disorders. At this early stage of its investigation, the parameters of stimulation that are most likely to be therapeutic, and its mechanisms of action, are not known. Published studies vary in the frequency, duration and extent of stimulation, with no firm guidelines about optimal parameters. Empirical study of the relative effects of stimulation at different frequencies, at different numbers of stimuli and for different durations is therefore important for the future development of this treatment. Such an investigation is best carried out in an animal model of depression for both ethical and practical reasons, as such studies in patients would possibly take many years and be extremely difficult to conduct. We propose such a study in rat models of depression which have demonstrated validity and utility in drug research. Rat models have a long track record in developing psychiatric treatments and are cost-effective and of proven value. We also plan to investigate the neuroanatomy of the immediate-early genes induced by TMS and compare it with electroconvulsive shock (ECS) and a tricyclic antidepressant, two established treatments of depression. The results will have implications for future human studies in guiding us toward the optimal parameters for therapeutic effects. They will also enhance our understanding of the mechanism of action of TMS in depression.Read moreRead less
Application Of Intelligent Conducting Polymers For Treating Schizophrenia And Allied Disorders Focusing On Neuronal Outgrowth, Myelination And Synaptogenesis
Funder
National Health and Medical Research Council
Funding Amount
$698,314.00
Summary
This project involves cross-disciplinary collaboration between researchers at the forefront of materials engineering, nanotechnology, neural pathology, human stem cell biology and mental health disciplines. We will use a nanodevice to apply electrical stimuli and growth factors to improve brain function in schizophrenia and allied disorders.
Topological Design of Mechanical Meta-Structures. This project aims to establish a new computational design methodology to address current challenges facing creation of ultralight structures with ultra-high-performance characteristics. The latest technologies in structural topology optimization and its correlated numerical simulation and structural analysis methods will be unified towards an integrated design framework. Expected outcomes include an advanced generative design platform for discove ....Topological Design of Mechanical Meta-Structures. This project aims to establish a new computational design methodology to address current challenges facing creation of ultralight structures with ultra-high-performance characteristics. The latest technologies in structural topology optimization and its correlated numerical simulation and structural analysis methods will be unified towards an integrated design framework. Expected outcomes include an advanced generative design platform for discovering novel geometries to underpin new meta-structure architectures, validated by appropriate fabrication techniques considering their geometric complexity. Such capabilities will benefit defence, civil, aerospace, energy and transport industries that pursue competitive advantage through innovation.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101683
Funder
Australian Research Council
Funding Amount
$448,354.00
Summary
Computational Design of Defect-Free Additive Manufactured Ceramic Structure. Despite its importance and potential, ceramic additive manufacturing (AM) is facing significant challenge for its inherent material characteristics prone to shrinkage and fracture during fabrication process. This project aims to fill a knowledge gap by developing a new computational design framework for a commonly-used indirect AM process. It will address a range of AM issues, such as residual stress/distortion, cracks, ....Computational Design of Defect-Free Additive Manufactured Ceramic Structure. Despite its importance and potential, ceramic additive manufacturing (AM) is facing significant challenge for its inherent material characteristics prone to shrinkage and fracture during fabrication process. This project aims to fill a knowledge gap by developing a new computational design framework for a commonly-used indirect AM process. It will address a range of AM issues, such as residual stress/distortion, cracks, and uncertainty in a nondeterministic context. The study is expected to establish novel design methodologies for ceramic AM with process modelling, robust/reliable optimisation, and fracture-based design. It will provide ceramic industry with a new framework for biomedical, aerospace and mechanical applications.Read moreRead less
Using 3D printing technology to develop architecturally-controlled synthetic bone substitutes. With the ageing population, there is increasing demand for synthetic materials that can regenerate bone. However, purely synthetic bone-substitute biomaterials cannot regenerate large bone defects in weight-bearing conditions due to their fragility. This project aims to develop a customisable, biodegradable, biocompatible and mechanically strong and tough scaffold that overcomes this long-standing prob ....Using 3D printing technology to develop architecturally-controlled synthetic bone substitutes. With the ageing population, there is increasing demand for synthetic materials that can regenerate bone. However, purely synthetic bone-substitute biomaterials cannot regenerate large bone defects in weight-bearing conditions due to their fragility. This project aims to develop a customisable, biodegradable, biocompatible and mechanically strong and tough scaffold that overcomes this long-standing problem. The project aims to achieve this by applying an innovative combination of cutting-edge 3D printing technology, advanced computational modelling and design techniques to produce a next-generation bioceramic scaffold with optimised architecture. This approach aims also to enable the possibility of producing custom-made implants for individual requirements.Read moreRead less
An experimental and theoretical programme of research to resolve major obstruction-to-flow problems in bins and stockpiles. Many of Australia's industries rely on the efficient storage and handling of bulk solids materials such as minerals, chemicals, food-stuffs, agricultural products and pharmeceuticals. Often the handling processes are inefficient to the extent of affecting the economics of the industry. Here we propose two projects addressing those inefficiences resulting from stable obstr ....An experimental and theoretical programme of research to resolve major obstruction-to-flow problems in bins and stockpiles. Many of Australia's industries rely on the efficient storage and handling of bulk solids materials such as minerals, chemicals, food-stuffs, agricultural products and pharmeceuticals. Often the handling processes are inefficient to the extent of affecting the economics of the industry. Here we propose two projects addressing those inefficiences resulting from stable obstructions, such as "rat-holes", and those experimental arising from the unusual flow characteristics of fine powders. The major objectives are to use experimental and advanced mathematical modelling techniques, to produce reliable design models which minimise the occurrence of stable obstructions and provide reliable methods for increasing fine powder flow rates.Read moreRead less