Self-assembled Hydrogels As A Model For Neurodegeneration
Funder
National Health and Medical Research Council
Funding Amount
$594,644.00
Summary
Alzheimer’s disease (AD) is a neurodegenerative disease which currently affects over 340,000 Australians. Often, symptoms of AD are not apparent until the disease is well advanced, limiting chances of successful treatment. In this project, hydrogels made from biocompatible peptides will be used to grow neural cell culture models to study the development of the disease in its early stages. This will help to develop new diagnostic tools for the early detection of AD.
Novel Biocompatible Nickel-free Shape Memory Alloy Scaffolds For Biomedical Applications
Funder
National Health and Medical Research Council
Funding Amount
$530,789.00
Summary
The current project is aimed at the development of a new class of novel biocompatible nickel-free shape memory alloy (SMA) scaffolds for metallic implant applications. The new scaffolds possess the ability to exert a mechanical force on the surrounding bones, and stimulate new bone tissue ingrowth, due to their shape memory effect, superelasticity and bone-mimicking porous structure. The outcomes from this project will provide innovative implant materials.
Micro-elastography - A New Tool For Microscopic Intraoperative Tumour Margin Assessment In Breast Cancer
Funder
National Health and Medical Research Council
Funding Amount
$195,956.00
Summary
In breast cancer surgery, it is vital to completely remove the entire tumour. Unfortunately, in 30% of breast-conserving surgeries, re-excision is required because microscopic analysis after the surgery indicated some tumour had been missed. This has traumatic consequences for the patient and places a huge economic burden on the healthcare system. Using micro-elastography, we will enable the surgeon to detect small regions of tumour during the initial surgery. This probe may significantly reduce ....In breast cancer surgery, it is vital to completely remove the entire tumour. Unfortunately, in 30% of breast-conserving surgeries, re-excision is required because microscopic analysis after the surgery indicated some tumour had been missed. This has traumatic consequences for the patient and places a huge economic burden on the healthcare system. Using micro-elastography, we will enable the surgeon to detect small regions of tumour during the initial surgery. This probe may significantly reduce the number of additional surgeries required.Read moreRead less
Improving Bionic Device Safety And Performance With Conductive Hydrogels
Funder
National Health and Medical Research Council
Funding Amount
$425,048.00
Summary
Bionic devices are being developed to treat a variety of neural disorders including blindness. Conductive hydrogels (CHs) are a new soft material developed by the CI to improve device performance and safety. This project will explore CH technologies with an aim of producing flexible organic electronics for high resolution devices, such as the bionic eye. Collaboration will be sought through industry, academia and clinical researchers to accelerate technology translation from bench to bedside.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668467
Funder
Australian Research Council
Funding Amount
$620,000.00
Summary
A large memory, high performance computing system for the ac3 Research Consortium. The installation of this new supercomputing facility is an important addition to the nation's foundation research infrastructure, and a further key system in the national computational grid. Of particular importance to research groups in NSW is the much needed boost in computational research and research training capacity that it will provide, enabling world leading research teams to continue their ground breakin ....A large memory, high performance computing system for the ac3 Research Consortium. The installation of this new supercomputing facility is an important addition to the nation's foundation research infrastructure, and a further key system in the national computational grid. Of particular importance to research groups in NSW is the much needed boost in computational research and research training capacity that it will provide, enabling world leading research teams to continue their ground breaking work in what is an increasingly competitive international environment. Much of the research to be supported lies in areas of national priority, including frontier technologies and Australian environmental sustainability.Read moreRead less
Computerised diffraction tomography for structural health monitoring. Structural health monitoring (SHM) offers the prospect of a quantum gain in performance and efficiency for the design and structural integrity management of high-value assets (e.g. aircraft). The aims of this project are to develop and validate efficient computational tools for:
(i) Characterising the scattering of the Lamb waves by defects or boundaries, and
(ii) Implementing robust and versatile approaches to tomographic i ....Computerised diffraction tomography for structural health monitoring. Structural health monitoring (SHM) offers the prospect of a quantum gain in performance and efficiency for the design and structural integrity management of high-value assets (e.g. aircraft). The aims of this project are to develop and validate efficient computational tools for:
(i) Characterising the scattering of the Lamb waves by defects or boundaries, and
(ii) Implementing robust and versatile approaches to tomographic imaging of laminar defects or damage from experimental/synthetic scattered field data.
This project will result in the development of a validated and versatile SHM system for quantifying damage that is analogous to computerised tomography in medical imaging.Read moreRead less
Active vibration control of a fluid loaded cylinder using inertial and reactive actuators. The active control technology outlined in this proposal presents a practical solution for low frequency noise problems associated with a submarine. The successful outcomes will be directly applicable to the Collins Class submarine, and thereby will greatly benefit Australia's naval defence industry. The active control transducer technology developed in this project will be patented, and has the potential t ....Active vibration control of a fluid loaded cylinder using inertial and reactive actuators. The active control technology outlined in this proposal presents a practical solution for low frequency noise problems associated with a submarine. The successful outcomes will be directly applicable to the Collins Class submarine, and thereby will greatly benefit Australia's naval defence industry. The active control transducer technology developed in this project will be patented, and has the potential to result in great commercial value for Australia. This project will contribute significantly to Australian research capacity in cutting-edge technologies in active vibration control. The collaboration between UNSW and the Maritime Platforms Division of DSTO will promote technology transfer and enhance Defence research expertise.Read moreRead less
Small Scale Turbulence. The thrust of the project is to gain a fundamental understanding of turbulence, which is the usual state of fluid motion. The focus will be principally on the smallest length scales of turbulence because of the potential that exists for developing a theoretical framework which can predict the behaviour of these scales accurately. Important insight will be gained into the manner in which temperature is mixed and convected by a turbulent flow.
In situ neutron diffraction mapping of tri-axial stress distributions in particulate systems. Compacting powders, which are critical in industries such as metal, advanced ceramic and pharmiceutical manufacturing, will be studied in real time using advanced neutron diffraction techniques. This will allow the three-dimensional mapping of stresses and strains within small volumes of the powder deep inside realistic compaction equipment.