How are microorganisms and nutrient cycling in saline soils affected by soil matric potential? Dryland agriculture is threatened by salinity and drought, and it is well-known that individually, both can decrease not only crop growth but also microbial activity and nutrient cycling which are critical for sustainability. As our climate becomes drier, it is necessary to understand how microbial activity and nutrient cycling in saline soils will be affected by drought and sporadic summer rainfall ev ....How are microorganisms and nutrient cycling in saline soils affected by soil matric potential? Dryland agriculture is threatened by salinity and drought, and it is well-known that individually, both can decrease not only crop growth but also microbial activity and nutrient cycling which are critical for sustainability. As our climate becomes drier, it is necessary to understand how microbial activity and nutrient cycling in saline soils will be affected by drought and sporadic summer rainfall events. As an international team of soil biologists, we will investigate the interactions between salinity and soil moisture on microbial activity and nutrient cycling. The results will provide insights into nutrient cycling in saline soils now and in the future and the benefit of amelioration strategies.Read moreRead less
The Role of the Single-Cell Environment in Microbial Invasion. This project aims to use a single-cell approach to develop a quantitative analysis of single-cell interactions to advance our understanding of complex bacterial behaviour fundamental to ecology, industry, technology and disease. Bacteria are ubiquitous on Earth and play key roles in nutrient cycles, biogeochemistry, pathogenesis, symbiosis and bioremediation among other processes. They exhibit complex behaviour and continuously invad ....The Role of the Single-Cell Environment in Microbial Invasion. This project aims to use a single-cell approach to develop a quantitative analysis of single-cell interactions to advance our understanding of complex bacterial behaviour fundamental to ecology, industry, technology and disease. Bacteria are ubiquitous on Earth and play key roles in nutrient cycles, biogeochemistry, pathogenesis, symbiosis and bioremediation among other processes. They exhibit complex behaviour and continuously invade animals, plants and new habitats. These behaviours are poorly understood in natural communities.Read moreRead less
Motility as a means to understand prokaryotic function in the biosphere. Bacterial processes are crucial to the environment, industry and technology of Australia. This work will open a new area of research to expand our understanding of how bacteria behave and function. This will lay the foundation for improved environmental management and resource utilisation in the critical areas of groundwater purification, coral infections, fisheries yields, petroleum remediation and bioenergy generation. Th ....Motility as a means to understand prokaryotic function in the biosphere. Bacterial processes are crucial to the environment, industry and technology of Australia. This work will open a new area of research to expand our understanding of how bacteria behave and function. This will lay the foundation for improved environmental management and resource utilisation in the critical areas of groundwater purification, coral infections, fisheries yields, petroleum remediation and bioenergy generation. This proposal will train over a dozen new scientists in these crucial areas and bring leading international scientists to Australia in the areas of bioenergy production, microfluidics, advanced microscopy and bioengineering.Read moreRead less
Geobiological gold cycling: Golden opportunities for the minerals industry. This project aims to develop new geobiological tools for gold exploration and processing that are rooted in a fundamental understanding of geobiological gold cycling. Given the high production costs, the sustainability of the Australian gold industry relies strongly on innovation. Yet, there are many gaps in our fundamental understanding of bio (geo)chemical gold dispersion and precipitation. This project aims to fill th ....Geobiological gold cycling: Golden opportunities for the minerals industry. This project aims to develop new geobiological tools for gold exploration and processing that are rooted in a fundamental understanding of geobiological gold cycling. Given the high production costs, the sustainability of the Australian gold industry relies strongly on innovation. Yet, there are many gaps in our fundamental understanding of bio (geo)chemical gold dispersion and precipitation. This project aims to fill these gaps by linking biochemical pathways of gold mobilisation and resistance in bacteria to its transport and biomineralisation. This would enable the development of protein-based biosensors, bioindicators and nanovectors. These would support the development of exploration and bioaccumulation technologies that allow more economically sustainable and environmentally viable mining practices, such as enhancing production from subeconomic ore.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150101574
Funder
Australian Research Council
Funding Amount
$368,583.00
Summary
Evolution and Adaptation of the Human Microbiome. The bacteria within the human body (microbiome) are vital to human health, and alterations to these intricate microbial communities are now associated with disease. Using ancient DNA, this project aims to examine the evolutionary history of the human microbiome by exploring ancient bacterial communities preserved in calcified dental plaque (calculus) over the past 10 000 years. This will provide valuable information that reveals how these bacteri ....Evolution and Adaptation of the Human Microbiome. The bacteria within the human body (microbiome) are vital to human health, and alterations to these intricate microbial communities are now associated with disease. Using ancient DNA, this project aims to examine the evolutionary history of the human microbiome by exploring ancient bacterial communities preserved in calcified dental plaque (calculus) over the past 10 000 years. This will provide valuable information that reveals how these bacterial communities respond to alterations in human diet, environment, culture, and location. By monitoring changes in a natural modern system, this project aims to determine how these microbial communities established themselves within the human body, elucidating how the microbiome may respond in the future.Read moreRead less
Stories from the past: the impact of industrialisation on the human microbiome. This project aims to explore the history and origin of ‘Industrial’ diseases such as obesity, diabetes, heart disease and autism. Non-communicable, ‘Industrial’ diseases are rising at an alarming rate in Australia, and changes to the beneficial microorganisms within the human body (microbiota) may be to blame. This project will explore how human microbiota have changed over the past 100 years in response to cultural, ....Stories from the past: the impact of industrialisation on the human microbiome. This project aims to explore the history and origin of ‘Industrial’ diseases such as obesity, diabetes, heart disease and autism. Non-communicable, ‘Industrial’ diseases are rising at an alarming rate in Australia, and changes to the beneficial microorganisms within the human body (microbiota) may be to blame. This project will explore how human microbiota have changed over the past 100 years in response to cultural, environmental, and lifestyle factors linked with Industrialisation. This approach will allow stories from the past to inform modern medical treatment strategies and public health decisions in the future. The project will identify changes in environment, diet, hygiene, and medicine that have altered human microbiota in the past and sparked the Industrial disease epidemic in Australia today.Read moreRead less
Keystone microbes and planktonic guilds in Australia's oceans. This project aims to unveil the ocean’s hidden sentinels, “keystone microbes” that underpin precious ecosystem services, and which can be used to monitor and model changes in ocean function. Marine microbes account for 90 per cent of oceanic biomass and every litre of seawater contains ~20,000 different species, but it is not known which species control ocean health and productivity. This project intends to provide definitive evidenc ....Keystone microbes and planktonic guilds in Australia's oceans. This project aims to unveil the ocean’s hidden sentinels, “keystone microbes” that underpin precious ecosystem services, and which can be used to monitor and model changes in ocean function. Marine microbes account for 90 per cent of oceanic biomass and every litre of seawater contains ~20,000 different species, but it is not known which species control ocean health and productivity. This project intends to provide definitive evidence of these keystones’ cellular level biogeochemical and metabolic capacity. Ultimately, this knowledge is expected to predict the resilience of ocean ecosystems and their response to change. The capacity to predict their dynamics will help provide investment clarity and increase healthy outcomes from activities involving human-ocean interactions such as recreation, food production and tourism.Read moreRead less
Diatom frustules: nanostructures at the base of ocean food webs. Molecules interacting with surfaces are fundamental to biological, chemical and physical processes, including desalinization membrane design, lab-on-a-chip systems, industrial catalysis, bioremediation, neurophysiology and uptake of nutrients for incorporation into food webs. Here, we use diatoms as models for molecule-surface interactions to find basic principles that underlay all of these interactions. This research will train st ....Diatom frustules: nanostructures at the base of ocean food webs. Molecules interacting with surfaces are fundamental to biological, chemical and physical processes, including desalinization membrane design, lab-on-a-chip systems, industrial catalysis, bioremediation, neurophysiology and uptake of nutrients for incorporation into food webs. Here, we use diatoms as models for molecule-surface interactions to find basic principles that underlay all of these interactions. This research will train students and scientists and establish collaborations with leading international scientists in the field.Read moreRead less
Is mass commercialisation of silver-based nanotechnology undermining its biomedical antibacterial potential? Silver nanoparticles have demonstrated broad spectrum antibacterial potential and are increasingly used in biomedical applications to limit infection. They are also found in a growing range of everyday products such as shampoos and socks. This situation is analogous to the previous use of antibiotics for nonmedical purposes and the subsequent spread of antibiotic resistant bacteria. This ....Is mass commercialisation of silver-based nanotechnology undermining its biomedical antibacterial potential? Silver nanoparticles have demonstrated broad spectrum antibacterial potential and are increasingly used in biomedical applications to limit infection. They are also found in a growing range of everyday products such as shampoos and socks. This situation is analogous to the previous use of antibiotics for nonmedical purposes and the subsequent spread of antibiotic resistant bacteria. This project will measure silver resistance selection pressure in key microbial communities. Novel monitoring devices, a multi-technique chemistry approach, and correlative synchrotron spectroscopy and molecular biology techniques will be used to decipher the environmental silver resistome and its likely significance.Read moreRead less
Microscale insights into ocean-scale processes: microbial behaviour as a driver of ocean biogeochemistry. Microscopic plankton regulate the ocean's chemical cycles, which ultimately support life on earth. However, the ecological interactions driving these processes are poorly understood. This project will use novel approaches to decipher the behaviours of marine microbes, providing a more complete perception of how ocean ecosystems operate and influence climate.