A Novel Point Of Care (PoC) Device For Predicting And Monitoring Bleeding And Clotting (haemostasis)
Funder
National Health and Medical Research Council
Funding Amount
$608,979.00
Summary
Manipulating the bleeding/clotting system is a critical but expensive part of modern medicine, eg some people need blood thinners while others can bleed too much. Thrombin generation is the ideal overall test for the bleeding/clotting of blood, but current methods have major problems. We developed and patented a test that deals with most of the problems. This proposal will create an assay that is easy for doctors to perform without a specialised laboratory.
The Voice As A Behavioural Probe Of Patient Functioning In Disorders Of The Central Nervous System
Funder
National Health and Medical Research Council
Funding Amount
$29,255.00
Summary
Health conditions like pain and depression are difficult to measure, yet we can hear in someone’s voice if they are upset or distressed. This study is looking to develop ways the voice can be used to track changes in a patient’s condition. By recording a speech sample and analyzing parts of the signal, we may be able to tell if a drug treatment for depression is working, or if a patient is experiencing less pain after therapy.
Development And Application Of A Novel Ultrasensitive LC-MS Estradiol Assay
Funder
National Health and Medical Research Council
Funding Amount
$240,400.00
Summary
This project will develop a new ultrasensitive method using liquid chromatography-mass spectrometry to measure extremely low level of circulating estrogens in the bloodstream especially in mice. This will allow for the first time the ability to study the natural regulation of fertility in mice and other sub-primate mammals for which the present assay methods are not adequate.
Risk Stratification Of Older People In Hospital: Validation And Influence On Clinical Decision Making
Funder
National Health and Medical Research Council
Funding Amount
$291,067.00
Summary
Older people in hospital are at high risk of adverse outcomes, a vulnerability commonly referred to as frailty. In community-dwelling older people, frailty status can be measured precisely with a Frailty Index score. This research aims to develop a Frailty Index from a standardised comprehensive geriatric assessment instrument used in the routine care of many patients in hospital. This would assist clinicians to identify vulnerable older inpatients, improving their care in the acute setting.
Microperimetry is a clinical tool for measuring central visual function whilst the retina is continuously monitored and retinal testing locus adjusted for eye movements. Regulatory authorities are now considering outcomes of microperimetry as a valid clinical trials endpoint in certain retinal conditions because visual acuity does not always reflect disease progression. This project will validate various types of microperimeters and determine how they should be used to monitor macular diseases.
An Australian Community Of Practice In Research In Dementia (ACcORD) To Improve Health Outcomes For People With Dementia And Their Carers
Funder
National Health and Medical Research Council
Funding Amount
$3,382,819.00
Summary
The ACcORD project brings together a multidisciplinary team to improve health and quality of life of people with dementia and their carers. A program of research driven by end users will be conducted across four key themes: 1) Development of measures for assessing unmet needs; 2) Exploring barriers to service delivery; 3) Medico-legal and financial impediments to providing care; and 4) Testing innovative strategies to improve health outcomes for people with dementia and their carers.
Sitting, Standing And Moving: Evaluating The Impact Of Health Enhancing Initiatives
Funder
National Health and Medical Research Council
Funding Amount
$314,644.00
Summary
Too much sitting is now identified as a significant health risk, prompting the development of policies and programs directed at reducing the amount of time adults spend sitting. However, evaluation of the effectiveness of these programs has been hampered by the relatively limited methods used to quantify changes in these behaviours. This fellowship aims to develop a set of best-practice measures for use across a variety of public health settings to evaluate changes in sitting and active time.
Centre Of Research Excellence In Alcohol And Other Drug Sector Capacity Building For Outcome Focused, Evidence Based And Cost Effective Care (CRE In AOD -CB)
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
AOD use is the number one risk factor for the most death and disability combined in all age groups in Australia. This CRE's mission is to reduce the burden and cost of primary and complex comorbid AOD problems in Australia, by using MBC to increase the capacity of the AOD sector to deliver evidence based, efficient and cost effective care to clients.