A Grid based platform for multi-scaled biological simulation. Heart disease currently affects over 3.5 million Australians. In 2006 it claimed the lives of almost 46,000 Australians (34% of all deaths). We will develop enabling technology that underpins cardiac disease research, offering potential for new treatments and pharmaceutical therapies. Even a small improvement in this area can translate into significant national benefit. Further, the mathematical techniques and software tools we will d ....A Grid based platform for multi-scaled biological simulation. Heart disease currently affects over 3.5 million Australians. In 2006 it claimed the lives of almost 46,000 Australians (34% of all deaths). We will develop enabling technology that underpins cardiac disease research, offering potential for new treatments and pharmaceutical therapies. Even a small improvement in this area can translate into significant national benefit. Further, the mathematical techniques and software tools we will develop, whilst focused on heart tissue, will have broader applicability, and may underpin advancements in other disciplines. Finally, we expect that the software solutions and infrastructure will have both commercial and strategic value in their own right.Read moreRead less
Algorithms and computation in four-dimensional topology. This project will establish Australia as a world leader in computational topology, particularly in the all-important areas of topology in three and four dimensions. In four dimensions this work will be truly groundbreaking; until now the field has seen little development due to the complexity of the algorithms and computations required, and the applicant is in the unique position of having the necessary tools to make significant progress ....Algorithms and computation in four-dimensional topology. This project will establish Australia as a world leader in computational topology, particularly in the all-important areas of topology in three and four dimensions. In four dimensions this work will be truly groundbreaking; until now the field has seen little development due to the complexity of the algorithms and computations required, and the applicant is in the unique position of having the necessary tools to make significant progress in a feasible time frame. In three dimensions this project will strengthen the distinguished computational topology community in Melbourne, led by pioneers such as Rubinstein, Goodman, Hodgson as well as the applicant himself.Read moreRead less
Quantum correlations in ultra-cold Fermi gases. The field of ultra-cold Fermi gases provides a unique opportunity to develop and test theoretical methods for novel experimental environments of exceptional purity and simplicity. This improved understanding will have potential applications in many fields, ranging from the astrophysics of neutron stars to condensed matter systems such as superconductors or nanostructures. Just as importantly, the project will develop linkages with world leading the ....Quantum correlations in ultra-cold Fermi gases. The field of ultra-cold Fermi gases provides a unique opportunity to develop and test theoretical methods for novel experimental environments of exceptional purity and simplicity. This improved understanding will have potential applications in many fields, ranging from the astrophysics of neutron stars to condensed matter systems such as superconductors or nanostructures. Just as importantly, the project will develop linkages with world leading theoretical groups, which will greatly aid research student education. There are direct applications to experiments on molecule formation with ultra-cold fermions in the ARC Centre of Excellence for Quantum-Atom Optics.Read moreRead less
Simulating viral evolution and genetic complexity. This project has direct relevance to understanding the growth of viral infections, and therefore has possible practical applications in disease research and control. Examples of these are emerging diseases in humans such as those caused by HIV-1, SARS coronavirus and Dengue virus, which cause considerable human suffering throughout the world. A major part of current research into these diseases involves attempts to model the evolutionary geneti ....Simulating viral evolution and genetic complexity. This project has direct relevance to understanding the growth of viral infections, and therefore has possible practical applications in disease research and control. Examples of these are emerging diseases in humans such as those caused by HIV-1, SARS coronavirus and Dengue virus, which cause considerable human suffering throughout the world. A major part of current research into these diseases involves attempts to model the evolutionary genetics and dynamics of virus populations in order to understand how to control epidemics, develop vaccines and design drugs. The research program is designed to provide new computational modelling tools for this purpose, which may have wider applications as well.
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Mathematical and computational models for agrichemical retention on plants. Mathematical and computational models for agrichemical retention on plants. This project aims to build interactive software that simulates agrichemical spraying for multiple virtual plants reconstructed from scanned data. Mathematical modelling and computer simulation could offer an alternative to expensive experimental programs for agrichemical spraying of plants. This project will use contemporary fluid mechanics to bu ....Mathematical and computational models for agrichemical retention on plants. Mathematical and computational models for agrichemical retention on plants. This project aims to build interactive software that simulates agrichemical spraying for multiple virtual plants reconstructed from scanned data. Mathematical modelling and computer simulation could offer an alternative to expensive experimental programs for agrichemical spraying of plants. This project will use contemporary fluid mechanics to build practical mathematical models for droplet impaction, spreading and evaporation on leaf surfaces, and experimentally calibrate and validate the models. The software is expected to drive the development of agrichemical products that increase retention, minimise environmental impacts, and reduce costs for end-users.Read moreRead less
Formal modelling and analysis of software requirements for air traffic management systems for improved integrity assurance. This project will significantly reduce the time and cost of developing software for critical applications such as aviation and air traffic management. As well as improving the trustworthiness of safety-critical computer-based systems, this project will also enable system improvements to be deployed faster and more reliably.
Understanding concurrent programs using rely-guarantee thinking. Multi-core processors are standard in computers and devices (e.g. smart phones) but much of the software available for these machines is either unreliable or does not exploit the available hardware parallelism. This project will devise techniques for designing concurrent software that exploits these platforms while delivering dependable operation.
Industrial Transformation Research Hubs - Grant ID: IH170100013
Funder
Australian Research Council
Funding Amount
$2,962,655.00
Summary
ARC Research Hub for Digital Enhanced Living. The ARC Research Hub for Digital Enhanced Living aims to address the growing challenges of aging people living in their own home or residential care. This will be through inventing new personalised medical technologies through an innovative approach, with a multi-disciplinary team leveraging diverse expertise. An enhanced capacity to create and deploy fit-for-purpose personalised health solutions will result in revenues from new and repurposed device ....ARC Research Hub for Digital Enhanced Living. The ARC Research Hub for Digital Enhanced Living aims to address the growing challenges of aging people living in their own home or residential care. This will be through inventing new personalised medical technologies through an innovative approach, with a multi-disciplinary team leveraging diverse expertise. An enhanced capacity to create and deploy fit-for-purpose personalised health solutions will result in revenues from new and repurposed devices, analytics and integration platforms. New jobs and improved care will see cost reductions, better use of resources and enhanced mental, physical and social well-being.Read moreRead less
Unlocking the potential for linear and discrete optimisation in knot theory and computational topology. Computational topology is a young, energetic field that uses computers to solve complex geometric problems, such as whether a loop of string is tangled. Such computations are becoming increasingly important in mathematics, and applications span biology, physics and information sciences, however many core problems in the field remain intractable for all but the simplest cases. This project unit ....Unlocking the potential for linear and discrete optimisation in knot theory and computational topology. Computational topology is a young, energetic field that uses computers to solve complex geometric problems, such as whether a loop of string is tangled. Such computations are becoming increasingly important in mathematics, and applications span biology, physics and information sciences, however many core problems in the field remain intractable for all but the simplest cases. This project unites geometric techniques with powerful methods from operations research, such as linear and discrete optimisation, to build fast, powerful tools that can for the first time systematically solve large topological problems. Theoretically, this project has significant impact on the famous open problem of detecting knottedness in fast polynomial time.Read moreRead less
An extensible framework for analysis of Java language-based security conformance. Java is a programming language and platform running on 3 billion devices. While Java provides a sandbox-based security architecture within the Java Class Library to protect systems from untrusted code downloaded from Internet, it cannot defend against implementation bugs that occur in the Java Class Library. The goal of this project is to provide a formal model of the Java security architecture, which can be used b ....An extensible framework for analysis of Java language-based security conformance. Java is a programming language and platform running on 3 billion devices. While Java provides a sandbox-based security architecture within the Java Class Library to protect systems from untrusted code downloaded from Internet, it cannot defend against implementation bugs that occur in the Java Class Library. The goal of this project is to provide a formal model of the Java security architecture, which can be used by program analysers to identify faulty or insufficient security checks in the Java Class Library that may lead to the sandbox being bypassed.Read moreRead less