Optimising Intervention Strategies To Reduce The Burden Of Group A Streptococcus In Aboriginal Communities
Funder
National Health and Medical Research Council
Funding Amount
$856,896.00
Summary
Skin sores are highly prevalent in remote Australian Indigenous communities and can lead to invasive infections and rheumatic heart disease. We will develop mathematical models to understand the transmission of skin sores, allowing us to define the optimal extent (household, community, region), timing and triggers for interventions to interrupt transmission. This will guide public health policy in reducing the prevalence of skin sores and scabies, and their accompanying disease burden.
Diseases caused by the pneumococcus represent the largest cause of vaccine preventable death in the world today, mainly pneumonia and meningitis. In 2011, 16 developing countries will introduce pneumococcal conjugate vaccines, none in east Asia. Lack of research has been a major barrier to their use in the region. We have established an international centre of excellence in the field and we seek support to extend the capacity of this group and to transfer the technology to Vietnam.
ARC Complex Open Systems Research Network. Complexity is the common frontier in the physical, biological and social sciences. This Network will link specialists in all three sciences through five generic conceptual and mathematical theme activities. It will promote research into how subsystems self-organise into new emergent structures when assembled into an open, non-equilibrium system. Outcomes will include new technologies and software tools and deeper understanding of fundamental questions i ....ARC Complex Open Systems Research Network. Complexity is the common frontier in the physical, biological and social sciences. This Network will link specialists in all three sciences through five generic conceptual and mathematical theme activities. It will promote research into how subsystems self-organise into new emergent structures when assembled into an open, non-equilibrium system. Outcomes will include new technologies and software tools and deeper understanding of fundamental questions in science. An essential function of the network will be introducing researchers end users to new tools and broadening the horizons of graduate students.Read moreRead less
Design of a Reference Methodology for Extended Enterprise Architecture. Enterprises have nowadays a very critical perception of the actual benefits of Information Technology (IT). Significant investments in IT infrastructures have been made. However, in many cases no monetary benefits could be demonstrated. Enterprises Architectures provide a way to link the business and the IT perspective. This project aims to develop an operational methodology with a solid theoretical foundation for the design ....Design of a Reference Methodology for Extended Enterprise Architecture. Enterprises have nowadays a very critical perception of the actual benefits of Information Technology (IT). Significant investments in IT infrastructures have been made. However, in many cases no monetary benefits could be demonstrated. Enterprises Architectures provide a way to link the business and the IT perspective. This project aims to develop an operational methodology with a solid theoretical foundation for the design of such Enterprise Architectures. The outcomes and the innovation of this project are an extension of the popular Zachman Framework. Integrated modelling techniques proposed within the Architecture of Integrated Information Systems will be used to populate this framework.Read moreRead less
Supersymmetry and supergravity: new approaches and applications. This project aims to advance our understanding of supersymmetric quantum field, gravity, and higher-spin theories. Supersymmetry and supergravity play crucial roles in modern developments in fundamental particle physics and cosmology. They also have rich connections with many branches of mathematical physics. Major conceptual questions in the description of general supergravity-matter couplings are still unsolved. By performing sta ....Supersymmetry and supergravity: new approaches and applications. This project aims to advance our understanding of supersymmetric quantum field, gravity, and higher-spin theories. Supersymmetry and supergravity play crucial roles in modern developments in fundamental particle physics and cosmology. They also have rich connections with many branches of mathematical physics. Major conceptual questions in the description of general supergravity-matter couplings are still unsolved. By performing state of the art analysis in supergravity and holographic dualities, the project will advance our understanding of quantum gravity, black holes, and cosmology placing Australia at the forefront of these important research fields.Read moreRead less
Eliminating Hepatitis C Transmission By Enhancing Hepatitis C Care And Treatment In Primary Health Care Settings.
Funder
National Health and Medical Research Council
Funding Amount
$1,221,831.00
Summary
In developed countries, people who inject drugs (PWID) are the group at greatest risk of hepatitis C (HCV) infection but few PWID receive HCV treatment. With the advent of highly effective non-interferon based treatments HCV elimination, although ambitious, is now being seriously considered globally. This partnership grant will explore the feasibility of eliminating HCV transmission by enhancing HCV care and treatment for PWID in primary health care settings.
Mathematical and computational models for agrichemical retention on plants. Mathematical and computational models for agrichemical retention on plants. This project aims to build interactive software that simulates agrichemical spraying for multiple virtual plants reconstructed from scanned data. Mathematical modelling and computer simulation could offer an alternative to expensive experimental programs for agrichemical spraying of plants. This project will use contemporary fluid mechanics to bu ....Mathematical and computational models for agrichemical retention on plants. Mathematical and computational models for agrichemical retention on plants. This project aims to build interactive software that simulates agrichemical spraying for multiple virtual plants reconstructed from scanned data. Mathematical modelling and computer simulation could offer an alternative to expensive experimental programs for agrichemical spraying of plants. This project will use contemporary fluid mechanics to build practical mathematical models for droplet impaction, spreading and evaporation on leaf surfaces, and experimentally calibrate and validate the models. The software is expected to drive the development of agrichemical products that increase retention, minimise environmental impacts, and reduce costs for end-users.Read moreRead less
Optimal management of corrosion and odour problems in sewer systems. Pollutants in wastewater undergo complex changes in sewers, leading to the production and release of odorous and corrosive compounds. Despite major efforts and expenditure by water utilities to mitigate these problems, odorous emissions from sewers are still commonly occurring in urban areas. Furthermore, the value of public assets is significantly diminished due to sewer corrosion, costing hundreds of millions of dollars a yea ....Optimal management of corrosion and odour problems in sewer systems. Pollutants in wastewater undergo complex changes in sewers, leading to the production and release of odorous and corrosive compounds. Despite major efforts and expenditure by water utilities to mitigate these problems, odorous emissions from sewers are still commonly occurring in urban areas. Furthermore, the value of public assets is significantly diminished due to sewer corrosion, costing hundreds of millions of dollars a year in Australia alone. This project is a major joint effort by the Australian water industry and world-leading scientists to generate advanced knowledge and develop effective technologies for optimal odour and corrosion management in sewers, delivering large social, environmental and economic benefits.Read moreRead less
Understanding and mitigating nitrous oxide emission from wastewater treatment plants. Climate change caused by greenhouse gas emissions is one of the most serious challenges that mankind is facing. Substantial reduction in emissions must be achieved, with responsibility to be shared by all industrial sectors. Wastewater systems contribute to greenhouse gas emissions through not only energy consumptions but also direct emissions of fugitive greenhouse gases such as nitrous oxide. This project aim ....Understanding and mitigating nitrous oxide emission from wastewater treatment plants. Climate change caused by greenhouse gas emissions is one of the most serious challenges that mankind is facing. Substantial reduction in emissions must be achieved, with responsibility to be shared by all industrial sectors. Wastewater systems contribute to greenhouse gas emissions through not only energy consumptions but also direct emissions of fugitive greenhouse gases such as nitrous oxide. This project aims to provide knowledge and technology support to the Australian wastewater industry to minimize the emission of nitrous oxide during biological nitrogen removal from wastewater. This is critically important for this industry to achieve greenhouse gas neutral wastewater management.Read moreRead less
Sewer corrosion reduction through model-supported ventilation control. Ventilation is one of the key technologies for sewer corrosion control. However, its design and operation are currently based on experience and empirical equations, often leading to unsatisfactory results. By integrating in-depth laboratory and pilot-sewer studies under defined conditions with extensive field investigations, this multidisciplinary project aims to develop critical models to predict the corrosion process in res ....Sewer corrosion reduction through model-supported ventilation control. Ventilation is one of the key technologies for sewer corrosion control. However, its design and operation are currently based on experience and empirical equations, often leading to unsatisfactory results. By integrating in-depth laboratory and pilot-sewer studies under defined conditions with extensive field investigations, this multidisciplinary project aims to develop critical models to predict the corrosion process in response to ventilation and dynamic wastewater and atmospheric conditions, enabling model-based sewer ventilation design and operation. The project also aims to deliver novel, field-demonstrated ventilation strategies. The project findings will be incorporated in the Australian ventilation design and operation guidelines.Read moreRead less