Erosion processes in soils across scales. This project aims to develop a monitoring tool for predicting the evolution of internal erosion in dams based on innovative electromagnetic observation methods. Internal erosion is an insidious process occurring in the obscurity of the soil’s pore system until its consequences become visible and threaten the stability of the dams. These water retaining structures are vital for the future water and energy supply for our society and their failure can be ca ....Erosion processes in soils across scales. This project aims to develop a monitoring tool for predicting the evolution of internal erosion in dams based on innovative electromagnetic observation methods. Internal erosion is an insidious process occurring in the obscurity of the soil’s pore system until its consequences become visible and threaten the stability of the dams. These water retaining structures are vital for the future water and energy supply for our society and their failure can be catastrophic. By establishing an improved understanding of internal erosion as a sequence of processes on various scales, from the onset of erosion until the failure of the structure, this project will place Australia at the forefront of dam safety assessment.Read moreRead less
Direct simulation of composite microstructures in fluid and elastic media. The proposed innovative computational methodology will improve the design and performance of a wide range of mechanisms and industrial processes involving particulate inclusions, from engineering to biological applications. The resultant technology will make a contribution to maintain and enhance Australia's role in the development of advanced engineering materials through manipulating their composite microstructures. The ....Direct simulation of composite microstructures in fluid and elastic media. The proposed innovative computational methodology will improve the design and performance of a wide range of mechanisms and industrial processes involving particulate inclusions, from engineering to biological applications. The resultant technology will make a contribution to maintain and enhance Australia's role in the development of advanced engineering materials through manipulating their composite microstructures. The proposed computational method will also lead to new opportunities for Australian companies that develop computer simulation software. Our researchers in computational mechanics will gain further opportunities to extend the advances this project will make.Read moreRead less
Frontiers in bone and joint regeneration. Key outcomes of this project will deliver innovative strategies for scaffold-based bone and cartilage engineering whilst contributing to the education of a new generation of bioengineers, biomaterial scientists and tissue engineers with a strong international profile.
Fundamentals and practical applications of hierarchically-structured bulk materials. Structured bulk materials are very promosing for process intensification. By using structured bulk materials instead of fine particles, this project will have the opportunity to realise hydrogen or methane storage at very low pressure, and significantly speed up the production of alternative transport fuels from syn gas.
Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microflu ....Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microfluidic platform technology for reproducibly producing targeted polymer nanocarriers having systematically varied properties, a dual-templating method for making targeted silica nanocapsules and new design of in vivo-mimicking 'Tissue Chips' for screening and evaluating the nanocarriers.Read moreRead less
Regenerating articular cartilage with smart hydrogels and fabrication technologies. Osteoarthritis affects over 1.6 million Australians and a cure remains elusive. Tissue engineering promises to regenerate joints, but issues with tissue quality, organisation and cost have led to limited clinical application. This project will develop new tissue fabrication technologies to engineer cartilage with appropriate organisation and lower costs.
Robust Bulk Thermoelectric Technology for Harvesting Waste Energy. This project aims to develop robust thermoelectric technology to harvest waste energy from the use of fossil fuels by (i) establishing new strategies for enhancing thermoelectric properties, (ii) creating mass-production synthesis to reduce the materials cost, and (iii) exploring computation methods to guide the device assembly. Its focus is to improve the average thermoelectric performance, overcome the brittleness of materials, ....Robust Bulk Thermoelectric Technology for Harvesting Waste Energy. This project aims to develop robust thermoelectric technology to harvest waste energy from the use of fossil fuels by (i) establishing new strategies for enhancing thermoelectric properties, (ii) creating mass-production synthesis to reduce the materials cost, and (iii) exploring computation methods to guide the device assembly. Its focus is to improve the average thermoelectric performance, overcome the brittleness of materials, and ensure thermal stability. This project expects to generate new knowledge in manipulating transport properties. The intended outcome of affordable, robust, and functional thermoelectrics can be used for recovering waste heat, which will significantly benefit Australia’s economy, environment, and energy industry.Read moreRead less
Platform technology to decode motor control through ultra high-field MRI. This project aims to advance our understanding of the poorly understood neural circuits that enable fine motor control in humans. To obtain this knowledge, new platform technology will be developed to capture the full kinematics of the hand during concurrent functional magnetic resonance imaging at ultra high-field. This device will allow testing of fundamental theories describing the canonical microcircuits involved in ha ....Platform technology to decode motor control through ultra high-field MRI. This project aims to advance our understanding of the poorly understood neural circuits that enable fine motor control in humans. To obtain this knowledge, new platform technology will be developed to capture the full kinematics of the hand during concurrent functional magnetic resonance imaging at ultra high-field. This device will allow testing of fundamental theories describing the canonical microcircuits involved in hand motion. Expected outcomes include new evidence of mirror neurons and observation of predictive error signals in the motor cortex. This new knowledge paves the way towards improved computer-brain interface technology which is likely to create benefits through translation to applications such as artificial limb control.Read moreRead less
Understanding the role of catalysts in the growth of epitaxial semiconductor nanowires and their hierarchical heterostructures. This Fellowship aims to comprehensively determine the role of catalysts during nanowire growth, solving the bottle-neck problem for growing device-applicable nanowires. In order to address this complicated scientific challenge, the project plans to collaborate with several world-leading researchers in different areas, such as growth, property measurements and modelling. ....Understanding the role of catalysts in the growth of epitaxial semiconductor nanowires and their hierarchical heterostructures. This Fellowship aims to comprehensively determine the role of catalysts during nanowire growth, solving the bottle-neck problem for growing device-applicable nanowires. In order to address this complicated scientific challenge, the project plans to collaborate with several world-leading researchers in different areas, such as growth, property measurements and modelling. The outcomes of this Fellowship will not only provide new science in terms of nanowire growth, but also provide guidelines for designing, developing and manufacturing nanowire-based nanostructures for future nanodevices and nanosystems. This is strategically important to place Australia at the forefront of developments on nanoscience and nanotechnology.Read moreRead less
Femoral microarchitecture, strength and locomotion in adult people. This project aims at unravelling the load bearing capacity of human femora microarchitecture. The project will quantify the relationship between geometry, microarchitecture, strain and strength in adult people during normal and accidental motor tasks using micro-computed-tomography images, motion data, supercomputing technology and multivariate statistic. It will benefit the design of novel implantable devices, enhance exercise ....Femoral microarchitecture, strength and locomotion in adult people. This project aims at unravelling the load bearing capacity of human femora microarchitecture. The project will quantify the relationship between geometry, microarchitecture, strain and strength in adult people during normal and accidental motor tasks using micro-computed-tomography images, motion data, supercomputing technology and multivariate statistic. It will benefit the design of novel implantable devices, enhance exercise therapies and diagnostic techniques for promoting hip strength. The project will contribute to the engineering of biological tissue and the development of high-strength and light-weight bio-inspired materials.Read moreRead less