Discovery Early Career Researcher Award - Grant ID: DE200101286
Funder
Australian Research Council
Funding Amount
$425,118.00
Summary
Conserving the evolutionary processes that generate coral reef biodiversity. Coral reefs have evolved to become the most biodiverse marine ecosystem we know. They now face an uncertain future due to escalating human impacts and this project aims to investigate how these disturbances change the evolutionary processes that generate and maintain life on the reef. Using an interdisciplinary approach, this project seeks to create new knowledge and demonstrate how evolutionary theory can be used to ad ....Conserving the evolutionary processes that generate coral reef biodiversity. Coral reefs have evolved to become the most biodiverse marine ecosystem we know. They now face an uncertain future due to escalating human impacts and this project aims to investigate how these disturbances change the evolutionary processes that generate and maintain life on the reef. Using an interdisciplinary approach, this project seeks to create new knowledge and demonstrate how evolutionary theory can be used to advance biodiversity conservation. Other expected outcomes include developing new techniques and an enhanced capacity to solve conservation problems through cross-disciplinary and cross-institutional collaborations. This should benefit the conservation of Australia’s coral reef biodiversity through improved management policies.Read moreRead less
Are good males bad females? Sexual conflict in hermaphrodites. Animal hermaphrodites (organisms that are both males and females) are extremely common and important from both an economic and ecological perspective but we know little about the evolution of this group. This project will examine how sexual conflict, so pervasive in organisms with separate sexes, affects the evolution of hermaphrodites.
Diversity of Salinispora actinobacteria producing pharmaceutically relevant natural products from Australian marine sponges. By investigating the distribution of marine microbial resources relevant to drug discovery, we will directly contribute to ARC's Research Priority I - An Environmentally Sustainable Australia Priority Goal and the Priority Goal 'Sustainable use of Australia's biodiversity'. We will determine sources of marine bacteria and their genes useful for discovery of new natural pro ....Diversity of Salinispora actinobacteria producing pharmaceutically relevant natural products from Australian marine sponges. By investigating the distribution of marine microbial resources relevant to drug discovery, we will directly contribute to ARC's Research Priority I - An Environmentally Sustainable Australia Priority Goal and the Priority Goal 'Sustainable use of Australia's biodiversity'. We will determine sources of marine bacteria and their genes useful for discovery of new natural products for treatment of human diseases. We will do this by understanding where new strains of Salinispora bacteria may be isolated and how they are distributed in association with Australian marine sponge fauna, and by determining the distribution and chemical and genetic diversity of novel marine Salinispora bacteria.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100516
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
Biodiversity, biogeography and molecular evolution on tropical reefs. This project aims to discover how evolutionary processes, biogeography and molecular change drive biodiversity patterns. Coral reefs support over 800,000 plant and animal species on <0.1% of the ocean. This project will examine how this biodiversity was formed by generating genomic data for reef building corals and reef associated fishes to reconstruct their evolutionary history. It will compare models of speciation, extinctio ....Biodiversity, biogeography and molecular evolution on tropical reefs. This project aims to discover how evolutionary processes, biogeography and molecular change drive biodiversity patterns. Coral reefs support over 800,000 plant and animal species on <0.1% of the ocean. This project will examine how this biodiversity was formed by generating genomic data for reef building corals and reef associated fishes to reconstruct their evolutionary history. It will compare models of speciation, extinction and range change among regions to determine how those processes contribute to the formation of biodiversity gradients and regional assemblage differences. The project expects that better understanding of evolutionary dynamics will inform conservation priorities.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150101150
Funder
Australian Research Council
Funding Amount
$362,000.00
Summary
Using sponge transcriptomes to understand ancestral animal development. The invention of a basic developmental program was likely a key step in the transition to multicellularity in animals, one of the major transitions in the tree of life. By combining next-generation sequencing of a representative panel of sponges and functional studies on an oviparous sponge, this project aims to identify gene interactions and networks that built the first animal embryos over 680 million years ago. Furthermor ....Using sponge transcriptomes to understand ancestral animal development. The invention of a basic developmental program was likely a key step in the transition to multicellularity in animals, one of the major transitions in the tree of life. By combining next-generation sequencing of a representative panel of sponges and functional studies on an oviparous sponge, this project aims to identify gene interactions and networks that built the first animal embryos over 680 million years ago. Furthermore, the role of Wingless (Wnt) signalling in patterning these ancestral embryos along a primordial anterior-posterior axis will be investigated. Piecing together the fundamental molecular machinery shared by all animal embryos will shed light on the molecular basis for the complex development of most animals on Earth.Read moreRead less
Evolutionary origin of stem cells and the emergence of animal complexity. The project aims to decipher the fundamental mechanisms governing stem cell specification and formation. All animals rely on stem cells to replenish, repair and regenerate tissues. Stem cells are also often a conduit to malignant tumours. This project seeks to uncover the rules governing stem cell formation through the study of a simple and ancient animal – the marine sponge Amphimedon queenslandica. The project plans to c ....Evolutionary origin of stem cells and the emergence of animal complexity. The project aims to decipher the fundamental mechanisms governing stem cell specification and formation. All animals rely on stem cells to replenish, repair and regenerate tissues. Stem cells are also often a conduit to malignant tumours. This project seeks to uncover the rules governing stem cell formation through the study of a simple and ancient animal – the marine sponge Amphimedon queenslandica. The project plans to combine insights from the simple, experimentally-tractable sponge stem cell system with existing knowledge of stem cell specification in humans and other animals, to reveal the essential features of stem cell formation. These insights may inform future pursuits to generate, control and use stem cells in cancer and regenerative medicines.Read moreRead less
Evolution of environmental regulation of cell states in animal life cycles. This project seeks to understand how the environment influences the fate of cells over an animal's life, and how this influence originated in animal evolution. Using a homegrown Australian model, a sea sponge from the Great Barrier Reef, and advanced multi-omic approaches (genomics plus cell biology), this project aims to uncover the mechanisms underlying global cell state changes that are induced through the interplay o ....Evolution of environmental regulation of cell states in animal life cycles. This project seeks to understand how the environment influences the fate of cells over an animal's life, and how this influence originated in animal evolution. Using a homegrown Australian model, a sea sponge from the Great Barrier Reef, and advanced multi-omic approaches (genomics plus cell biology), this project aims to uncover the mechanisms underlying global cell state changes that are induced through the interplay of environmental and endogenous signals at metamorphosis. Because of the evolutionary position of sponges, outcomes of this project expect to reveal the cardinal rules governing environmentally-induced cell state changes that are obligatory for most animals to complete their complex life cycles.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150101266
Funder
Australian Research Council
Funding Amount
$358,536.00
Summary
Evolutionary and environmental basis of CO2 tolerance in coral reef fishes. This project aims to examine the effects of ocean acidification on coral reef fishes due to increasing atmospheric carbon dioxide (CO2). Physiological performance of fish vary under elevated CO2, but behaviour is consistently, negatively impacted. This project aims to investigate evolutionary trade-offs between behaviour and performance, physiological mechanisms key to compromising, maintaining, or enhancing metabolic pe ....Evolutionary and environmental basis of CO2 tolerance in coral reef fishes. This project aims to examine the effects of ocean acidification on coral reef fishes due to increasing atmospheric carbon dioxide (CO2). Physiological performance of fish vary under elevated CO2, but behaviour is consistently, negatively impacted. This project aims to investigate evolutionary trade-offs between behaviour and performance, physiological mechanisms key to compromising, maintaining, or enhancing metabolic performance under elevated CO2, and the importance of habitat in how fish respond to elevated CO2. As fish play critical roles in marine ecosystems by structuring food webs and driving ecological processes, this information will be critical for predicting the effects of ocean acidification on marine ecosystems and biodiversity.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100083
Funder
Australian Research Council
Funding Amount
$540,000.00
Summary
A high throughput phenomics facility for pace of life traits in animals. A high throughput phenomics facility for pace of life traits in animals: This project seeks to create the first high-throughput phenomic facility for animals in Australia. The molecular revolution has brought unprecedented capacity to understand genetic variation. Genetic variation is now better understood and more easily and cheaply characterised than the physical traits that organisms exhibit. Linking phenotypic variation ....A high throughput phenomics facility for pace of life traits in animals. A high throughput phenomics facility for pace of life traits in animals: This project seeks to create the first high-throughput phenomic facility for animals in Australia. The molecular revolution has brought unprecedented capacity to understand genetic variation. Genetic variation is now better understood and more easily and cheaply characterised than the physical traits that organisms exhibit. Linking phenotypic variation to genetic variation represents the major challenge in harnessing the power of the biomolecular age. This facility will accommodate animals from marine, freshwater and terrestrial systems across a diverse array of phyla. It will allow Australian researchers to leverage advances in high throughput genomic technologies to address a major bottleneck in biology.Read moreRead less