Synthetic genes as reference standards for biology and biomanufacture. Reference standards are needed to improve the measurement of biology and the reliability of biomanufacturing processes. This project aims to engineer synthetic genes capable of acting as reference standards for DNA, RNA and protein. The synthetic genes can be transcribed into mRNA standards, and translated into protein standards, and be further integrated into living cells to measure internal cellular processes.
The outcomes ....Synthetic genes as reference standards for biology and biomanufacture. Reference standards are needed to improve the measurement of biology and the reliability of biomanufacturing processes. This project aims to engineer synthetic genes capable of acting as reference standards for DNA, RNA and protein. The synthetic genes can be transcribed into mRNA standards, and translated into protein standards, and be further integrated into living cells to measure internal cellular processes.
The outcomes include a unified understanding of gene expression and more accurate next-generation sequencing and mass-spectrophotometry technologies. The synthetic genes also allow standardisation and optimisation of biomanufacturing processes that will produce mRNA and biologics products at a higher purity and lower cost.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180101595
Funder
Australian Research Council
Funding Amount
$364,446.00
Summary
Knowledge-embedded motion planning for smart construction machinery. This project aims to develop a novel sensory feedback-based planning approach for construction machinery to optimise site execution effectiveness. The project will investigate current motion planning approaches which are feasible as planning tools but fail to be implemented at construction sites due to uncertainties of actual operations. The expected outcome will be a practical planning approach validated through field tests an ....Knowledge-embedded motion planning for smart construction machinery. This project aims to develop a novel sensory feedback-based planning approach for construction machinery to optimise site execution effectiveness. The project will investigate current motion planning approaches which are feasible as planning tools but fail to be implemented at construction sites due to uncertainties of actual operations. The expected outcome will be a practical planning approach validated through field tests and help solve feasibility problems in handling deviations between plans and on-site executions.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210101896
Funder
Australian Research Council
Funding Amount
$436,875.00
Summary
Interface engineering of 2D materials for advanced battery application. The fast-growing energy storage market demands new devices with both high energy and power density. This project aims to understand and then engineering electrode-electrolyte interfaces using novel two-dimensional (2D) materials to achieve accelerated ion transport and enhanced surface redox reactions. Advanced in-situ and ex-situ characterization tools, including X-ray scattering, neutron scattering, and terahertz time-doma ....Interface engineering of 2D materials for advanced battery application. The fast-growing energy storage market demands new devices with both high energy and power density. This project aims to understand and then engineering electrode-electrolyte interfaces using novel two-dimensional (2D) materials to achieve accelerated ion transport and enhanced surface redox reactions. Advanced in-situ and ex-situ characterization tools, including X-ray scattering, neutron scattering, and terahertz time-domain spectroscopy, will be employed to study energy storage mechanisms. Novel solid-state batteries will be demonstrated based on well-designed electrodes using 2D materials. This project will boost the standing of Australia in the global competition of developing more efficient energy storage devices. Read moreRead less
Preparing Carbon Molecular Sieve Membrane (CMSM) for Olefin/Paraffin Separation. Carbon molecular sieve membrane (CMSM) presents superior selectivity and stability for many gas separation processes. This technology is energy saving, environmental friendly and with minimal operating cost. The project will develop CMSMs for the separation of olefin/paraffin, particularly, the propane/propylene mixture which is currently separated by the energy intensive cryogenic distillation in industry. The pro ....Preparing Carbon Molecular Sieve Membrane (CMSM) for Olefin/Paraffin Separation. Carbon molecular sieve membrane (CMSM) presents superior selectivity and stability for many gas separation processes. This technology is energy saving, environmental friendly and with minimal operating cost. The project will develop CMSMs for the separation of olefin/paraffin, particularly, the propane/propylene mixture which is currently separated by the energy intensive cryogenic distillation in industry. The project involves both experimental works and theoretical studies and will provide: (1) techniques for preparing CMSMs for olefin/paraffin separation; (2) methods characterizing the micro-structure of CMSMs; (3) mathematical models predicting multicomponent gas permeation/separation properties on CMSMs; (4) effect of impurities on the separation processes. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100849
Funder
Australian Research Council
Funding Amount
$364,000.00
Summary
Advanced thermal protection systems to enable Mars return missions. This project aims to advance the modelling of spacecraft heat shield performance to enable future returns to Earth from Mars, where vehicles will encounter heating loads an order of magnitude higher than Lunar returns. Survival depends on sacrificial heat shields which intentionally lose mass through ablation to form a protective layer. Currently, this process cannot be predicted accurately leading to compromised safety, excessi ....Advanced thermal protection systems to enable Mars return missions. This project aims to advance the modelling of spacecraft heat shield performance to enable future returns to Earth from Mars, where vehicles will encounter heating loads an order of magnitude higher than Lunar returns. Survival depends on sacrificial heat shields which intentionally lose mass through ablation to form a protective layer. Currently, this process cannot be predicted accurately leading to compromised safety, excessive weight, and increased mission cost. The expected outcome is an ablation model for vehicle design which, for the first time, is based on experiments with a realistic aerodynamic flow. The significance and benefit of this project is its potential to make ambitious missions such as a Mars return feasible.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220100379
Funder
Australian Research Council
Funding Amount
$420,582.00
Summary
Missing link in the chain: Gateway to the Satellite-Internet Constellations. This project aims to develop affordable and compact, reconfigurable antenna systems for satellite-terminals. With unprecedented performance, the wide bandwidth of operation, and low cost of production, the resulting antenna systems will act as the ‘enabling’ chip in providing internet connectivity to millions of people, who are unconnected or poorly connected at present. High-speed internet is not a reality outside dens ....Missing link in the chain: Gateway to the Satellite-Internet Constellations. This project aims to develop affordable and compact, reconfigurable antenna systems for satellite-terminals. With unprecedented performance, the wide bandwidth of operation, and low cost of production, the resulting antenna systems will act as the ‘enabling’ chip in providing internet connectivity to millions of people, who are unconnected or poorly connected at present. High-speed internet is not a reality outside densely populated areas, even today. The outcomes will close the digital divide, increase Australia’s economic and intellectual standing internationally, generate socio-economic benefits by empowering regional populations, increase the economic viability and remote-jobs outside metropolitan cities, and develop tourism.Read moreRead less