Outcomes Of Treatment Decisions And Prediction Of Individual Treatment Response In Multiple Sclerosis
Funder
National Health and Medical Research Council
Funding Amount
$92,358.00
Summary
Multiple sclerosis is the most common cause of neurological disability among young people. With the increasing choice of therapies, the goal of freedom from disease has become more realistic. We will use the MSBase international multiple sclerosis registry to identify optimal, individually-tailored therapeutic strategies. We will also implement volumetric magnetic resonance imaging in routine practice, thus translating a research tool into an instrument available to patients and their doctors.
Investigating Implementation Of 2017 Stroke Clinical Guidelines In Inpatient Stroke Rehabilitation
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
There are major problems in Australia and overseas of patients not receiving evidence-based care. In the first 3 months after a stroke, receiving more therapy helps people improve. People in stroke rehabilitation should receive 3 hours therapy/day, but this does not usually happen. This project will use rigorous research methods to work with stroke survivors, their carers and staff in rehabilitation hospitals to find the best way to ensure that each stroke survivor does 3 hours of practice/day.
Application Of Genomic Technologies For The Diagnosis And Management Of Genetic Heart Diseases.
Funder
National Health and Medical Research Council
Funding Amount
$438,768.00
Summary
The purpose of this research study is to investigate clinical and genetic factors which may predispose to important cardiac events such as dangerous arrhythmias, heart failure, heart transplantation or sudden cardiac death in patients with genetic heart diseases. It is possible that there are important risk factors or genetic findings which may be identified either through newer technologies which help cardiologists determine which patients and families are most at risk.
Improving Warfarin Management- Identifying Risk Factors For Bleeding And Improving Monitoring Mechanisms
Funder
National Health and Medical Research Council
Funding Amount
$291,309.00
Summary
Warfarin is a drug commonly used in the elderly to prevent blood clots. While a very effective drug, it is also a dangerous drug and should be closely monitored. While we know many of the reasons why problems occur, we do not know whether organisation of care, mental health or social issues such as community support influence how well warfarin is managed. These are important questions to answer, so that we can make significant inroads into preventing death and disability from warfarin.
Further Development, Evaluation And Dissemination Of The Chinese Peers For Progress Diabetes Program
Funder
National Health and Medical Research Council
Funding Amount
$219,961.00
Summary
This research will train diabetes patients who are becoming volunteer peer leaders (who lead face-to face peer group meetings and activities to help group members) in effective management of key self-care behaviors, which include taking prescribed medications, following diet and exercise regimens, blood glycemic self-monitoring, and coping emotionally with the rigors of living with diabetes.
Investigating The Utility Of Therapeutic Drug Monitoring Of Beta-lactam Antibiotics In Hospitalised Patients
Funder
National Health and Medical Research Council
Funding Amount
$215,887.00
Summary
The appropriate dosing of antibiotics for patients admitted to hospital is based on broad guidelines derived from studies in healthy volunteers or in patients that may have different types of infections. Minor changes in the clinical state of the patients can require significant dosing adjustments. The best way to guarantee appropriate antibiotic therapy is to individualize doses based on blood concentration data. We aim to determine the utility of dose adjustment in hospitalized patients.