Suboptimal Sleep And Unhealthy Brain Ageing: Improving Outcomes Through Treatment
Funder
National Health and Medical Research Council
Funding Amount
$632,705.00
Summary
My research will address limitations in our understanding of the impact of sleep characteristics on memory and thinking abilities and biological markers of brain health in older adults, by; 1) exploring these relationships over time, and 2) enabling direct assessment of the effect of improved sleep on memory and thinking, and markers of brain health, following sleep-improvement therapy. My results will contribute to the development of strategies aimed at promoting healthy brain ageing.
Harnessing Imaging And IT Strategies To Expedite Targeted Treatment And Improve Outcomes In Cerebrovascular Diseases
Funder
National Health and Medical Research Council
Funding Amount
$2,914,215.00
Summary
This project will expand on my 25+ years of research in combining neuroimaging methods such as CT and MRI with nascent software tools to better target and coordinate treatment and achieve improved outcomes in cerebrovascular diseases such as stroke. We will develop & improve new CT and MRI methods and leverage latest advances in computer science, such as deep learning and mobile phone app technology, to achieve faster and more accurate identification of patients who can benefit from treatment.
A Network Approach To Mapping And Modifying Brain Changes In Psychosis
Funder
National Health and Medical Research Council
Funding Amount
$2,163,245.00
Summary
Psychosis fundamentally alters a person’s relationship with reality. Brain scans can map which parts of the brain are affected by psychosis, but they cannot reveal the actual disease processes that cause these changes. I will address this gap by integrating brain imaging with genetics and mathematical modelling to identify the brain circuits and molecules that impact risk for psychosis, and to develop targeted therapies that modify risk-related brain dysfunction.
New physics with strongly correlated and spin-orbit-coupled electrons. This project aims to identify new physics in quantum magnets and emergent phenomena in solids where the electrons are strongly coupled and intertwined in a complex manner. As a consequence, quantum effects are dramatically enhanced and, in certain situations, force the electrons to split into different exotic particles. This project expects to identify suitable physical systems, candidate materials and appropriate conditions ....New physics with strongly correlated and spin-orbit-coupled electrons. This project aims to identify new physics in quantum magnets and emergent phenomena in solids where the electrons are strongly coupled and intertwined in a complex manner. As a consequence, quantum effects are dramatically enhanced and, in certain situations, force the electrons to split into different exotic particles. This project expects to identify suitable physical systems, candidate materials and appropriate conditions required for the experimental observation of this phenomena with neutron scattering methods. The advanced materials and exotic particles identified in this project will inform the development of next generation technologies, becoming the quantum bits in future quantum computers.Read moreRead less
Exciton-mediated room-temperature superconductivity . Superconductivity is the ability of an electronic material to conduct electrical current without resistance. This property underpins many existing and proposed technological applications, ranging from medical imaging to low-energy electronics and quantum computing. In this project, we aim to demonstrate a highly unconventional route towards superconductivity at room temperature and atmospheric pressure, by exploiting collective behaviour of e ....Exciton-mediated room-temperature superconductivity . Superconductivity is the ability of an electronic material to conduct electrical current without resistance. This property underpins many existing and proposed technological applications, ranging from medical imaging to low-energy electronics and quantum computing. In this project, we aim to demonstrate a highly unconventional route towards superconductivity at room temperature and atmospheric pressure, by exploiting collective behaviour of excitons (electron-hole pairs in a semiconductor) strongly coupled to photons. This research should help to overcome the biggest challenge for the widespread applications of superconductors: the very low temperature or extreme pressure that the superconducting materials need to function.Read moreRead less