Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775481
Funder
Australian Research Council
Funding Amount
$304,000.00
Summary
X-ray Molecular Structure Elucidation Facility (MSEF). X-ray diffraction plays a key role in identification and molecular characterization. X-ray techniques are the single most widely used analytical resource in structure determination and provide invaluable information for scientists working in the fields of synthesis, nanotechnology, polymer chemistry, and protein chemistry amongst many others. The facility brings together a multidisciplinary team of scientists and provides state-of-the-art re ....X-ray Molecular Structure Elucidation Facility (MSEF). X-ray diffraction plays a key role in identification and molecular characterization. X-ray techniques are the single most widely used analytical resource in structure determination and provide invaluable information for scientists working in the fields of synthesis, nanotechnology, polymer chemistry, and protein chemistry amongst many others. The facility brings together a multidisciplinary team of scientists and provides state-of-the-art research and training facilities.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882576
Funder
Australian Research Council
Funding Amount
$588,000.00
Summary
Polymer Characterization Facility (PCF). Future development of macromolecular and biotechnologies have the potential to revolutionize everyday life. Current applications include plastics for engineering, diagnostic devices for biochemical analysis, polymer therapeutics for drug delivery and prosthesis with specific functions. The proposed facility will provide the analytical tools required to probe and develop advanced materials with application in medicine, agriculture, composites, cosmetics, ....Polymer Characterization Facility (PCF). Future development of macromolecular and biotechnologies have the potential to revolutionize everyday life. Current applications include plastics for engineering, diagnostic devices for biochemical analysis, polymer therapeutics for drug delivery and prosthesis with specific functions. The proposed facility will provide the analytical tools required to probe and develop advanced materials with application in medicine, agriculture, composites, cosmetics, communications and electronics.Read moreRead less
Membrane-associated structure and the effect of metals on Abeta peptide from Alzheimer's disease. Alzheimer's disease currently affects 5% of Australians over 65, and will triple by year 2050 without an effective therapy. Much research to understand the causes of the disease has focused on the distinctive amyloid deposits found in patients' cerebral tissue. Recent evidence suggests that nerve cell death is actually directly caused by soluble forms of the protein fragments and metals that form th ....Membrane-associated structure and the effect of metals on Abeta peptide from Alzheimer's disease. Alzheimer's disease currently affects 5% of Australians over 65, and will triple by year 2050 without an effective therapy. Much research to understand the causes of the disease has focused on the distinctive amyloid deposits found in patients' cerebral tissue. Recent evidence suggests that nerve cell death is actually directly caused by soluble forms of the protein fragments and metals that form these deposits. We will investigate the specific molecular structure of these fragments with metals in relation to vesicles which mimic the nerve cell surface. This information may facilitate future biomedical efforts work to develop therapies, as well as develop general techniques to study similar structural problems.Read moreRead less