Novel Hybrid Nanotechnologies by Infiltration of Functional Polymers. Hybrid inorganic-organic materials have important applications in energy, environmental and health technologies. Sequential infiltration synthesis (SIS) of polymers is a recently introduced approach to preparing such hybrid structures. Advancement in the field is however hampered by lack of fundamental understanding of the mechanisms of interactions of SIS molecules with polymers, and the narrow range of polymers studied so fa ....Novel Hybrid Nanotechnologies by Infiltration of Functional Polymers. Hybrid inorganic-organic materials have important applications in energy, environmental and health technologies. Sequential infiltration synthesis (SIS) of polymers is a recently introduced approach to preparing such hybrid structures. Advancement in the field is however hampered by lack of fundamental understanding of the mechanisms of interactions of SIS molecules with polymers, and the narrow range of polymers studied so far. This project aims to build a fundamental framework for the development of SIS through systematic studies of interactions of polymers and SIS molecules. Expected outcomes include new methods for constructing nanostructures using functional polymers and novel fabrication processes exploiting polymer self-assembly.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101105
Funder
Australian Research Council
Funding Amount
$422,318.00
Summary
Developing Polymer Electrolytes for Operational All-Solid-State Batteries. This project aims to advance the development of safe rechargeable all-solid-state batteries (ASSBs) by innovating fluorinated block copolymers as solid-state electrolytes. ASSBs are the most promising power source for emerging energy storage goals, however, low ionic conductivity and poor long-term cycling stability are critical bottlenecks to their successful application. This project seeks to tackle these challenges by ....Developing Polymer Electrolytes for Operational All-Solid-State Batteries. This project aims to advance the development of safe rechargeable all-solid-state batteries (ASSBs) by innovating fluorinated block copolymers as solid-state electrolytes. ASSBs are the most promising power source for emerging energy storage goals, however, low ionic conductivity and poor long-term cycling stability are critical bottlenecks to their successful application. This project seeks to tackle these challenges by fabricating unique ionic conduction channels and stabilising electrode-electrolyte interfaces using fluorinated block copolymer electrolytes. The expected outcomes are new knowledge in polymer electrolytes and advancement in the commercialisation of ASSBs toward more efficient, safe and reliable energy storage technologies.Read moreRead less
Bio-inspired Nanoparticles for Mechano-Regulation of Stem Cell Fate. Mechanical stimulation plays a critical role in regulating stem cell fate. Nanostructure-mediated mechanical cues can precisely stimulate stem cells, but predicting their impact on stem cell differentiation is challenging. This project aims to engineer nanostructures to regulate stem cell fate and gain a fundamental understanding of the mechanical properties that affect cell function. The expected outcomes and benefits of this ....Bio-inspired Nanoparticles for Mechano-Regulation of Stem Cell Fate. Mechanical stimulation plays a critical role in regulating stem cell fate. Nanostructure-mediated mechanical cues can precisely stimulate stem cells, but predicting their impact on stem cell differentiation is challenging. This project aims to engineer nanostructures to regulate stem cell fate and gain a fundamental understanding of the mechanical properties that affect cell function. The expected outcomes and benefits of this project include a new fundamental understanding of the effect of mechanical properties on cell function, novel insights into the regulation of stem cell fate, and the development of a new class of roughness-tunable materials suitable for use in tissue engineering and pharmaceutical applications. Read moreRead less
Precision-engineered hybrid core-shell materials . This project aims to develop new platform technologies for making nanostructured hybrid core-shell materials with exceptionally high drug loading and programmed release. Building on this research team's recent breakthrough in the precision engineering of core-shell materials, this research will revolutionise current approaches for making drug-loaded polymer and inorganic particles. Significant outcomes will include a novel sequential nanoprecipi ....Precision-engineered hybrid core-shell materials . This project aims to develop new platform technologies for making nanostructured hybrid core-shell materials with exceptionally high drug loading and programmed release. Building on this research team's recent breakthrough in the precision engineering of core-shell materials, this research will revolutionise current approaches for making drug-loaded polymer and inorganic particles. Significant outcomes will include a novel sequential nanoprecipitation platform technology for making drug-core polymer-shell nanoparticles, and a new bio-inspired approach for making hybrid drug-core silica-shell nanocomposites, and new materials for applications in programmed release and delivery systems.Read moreRead less
Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fu ....Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fundamentally understand the relationship between physical-chemical properties and efficacy. Completion of this project aims to produce potent nanoparticle-based adjuvants underpinned by novel manufacturing technology, to ultimately facilitate the development of more effective and protective vaccines for animals and humans.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL230100095
Funder
Australian Research Council
Funding Amount
$3,095,070.00
Summary
Materials Nanotectonics: Designing Conductive Inorganic Porous Materials. This project aims to develop the next generation of conductive porous materials through an integrated approach which combines inorganic synthesis with informatics. Using this approach, transition metals can be combined with nonmetals creating mesoporous materials with precise control of their internal space allowing the correlations between structure, composition, properties, and performance to be revealed. This project is ....Materials Nanotectonics: Designing Conductive Inorganic Porous Materials. This project aims to develop the next generation of conductive porous materials through an integrated approach which combines inorganic synthesis with informatics. Using this approach, transition metals can be combined with nonmetals creating mesoporous materials with precise control of their internal space allowing the correlations between structure, composition, properties, and performance to be revealed. This project is expected to generate new highly efficient electrocatalysts and energy conversion devices based on low-cost and earth-abundant transition metals. The project outcomes will position Australia at the forefront of research and development in advanced materials, smart catalysts, and renewable energy technologies.Read moreRead less
Photoelectrode design for solar driven methane to methanol conversion. This project aims to achieve efficient photoelectrocatalytic partial oxidation of greenhouse gas methane for methanol production with high selectivity. The program will design new semiconductor materials through rational defect engineering and co-catalyst selection to revolutionise methane conversion. The expected outcomes include sustainable processes to convert methane into valuable liquid chemicals like methanol, and compr ....Photoelectrode design for solar driven methane to methanol conversion. This project aims to achieve efficient photoelectrocatalytic partial oxidation of greenhouse gas methane for methanol production with high selectivity. The program will design new semiconductor materials through rational defect engineering and co-catalyst selection to revolutionise methane conversion. The expected outcomes include sustainable processes to convert methane into valuable liquid chemicals like methanol, and comprehensive understanding on functional material design for solar driven catalytic reactions. The significant benefits will include revolutionary methane mitigation technologies and sustainable processes for value-added chemical production, alleviating key environmental and energy challenges facing Australia and the world.Read moreRead less
Next-generation lithography: photo-directing assembly of block copolymers. This project aims to introduce a novel approach to organising block polymers through the photochemical modification of the surface of a photo-sensitive polymer. Chemo-epitaxy is the science of organising materials on a surface decorated with chemical patterns. The process has the potential to revolutionise the manufacture of integrated circuits, enabling faster processors. This project expects to introduce innovative conc ....Next-generation lithography: photo-directing assembly of block copolymers. This project aims to introduce a novel approach to organising block polymers through the photochemical modification of the surface of a photo-sensitive polymer. Chemo-epitaxy is the science of organising materials on a surface decorated with chemical patterns. The process has the potential to revolutionise the manufacture of integrated circuits, enabling faster processors. This project expects to introduce innovative concepts in polymer chemistry and nanoscale assembly with the potential to advance a multi-billion-dollar industry.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100042
Funder
Australian Research Council
Funding Amount
$970,000.00
Summary
Cryo-Focused Ion Beam Facility for soft and hard materials. The multipurpose Cryo-Focused Ion beam scanning electron microscope (Cryo-FIB) Facility aims to provide revolutionary insights into beam sensitive materials and biological molecules at high magnification. This instrument will be a unique configuration and the most advanced of its kind in Australia. It will be fitted with a gallium ion source, cryo-stage, cryo-lift out and cryo-transfer suite and capable of imaging and compositional anal ....Cryo-Focused Ion Beam Facility for soft and hard materials. The multipurpose Cryo-Focused Ion beam scanning electron microscope (Cryo-FIB) Facility aims to provide revolutionary insights into beam sensitive materials and biological molecules at high magnification. This instrument will be a unique configuration and the most advanced of its kind in Australia. It will be fitted with a gallium ion source, cryo-stage, cryo-lift out and cryo-transfer suite and capable of imaging and compositional analysis in two- and three-dimensions and preparing samples for atomic-scale analyses with complementary cryo-microscopies. This equipment aims to facilitate innovative research in the fields of energy materials, advanced manufacturing, nanomaterials and in situ cell and structural biology.Read moreRead less
Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microflu ....Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microfluidic platform technology for reproducibly producing targeted polymer nanocarriers having systematically varied properties, a dual-templating method for making targeted silica nanocapsules and new design of in vivo-mimicking 'Tissue Chips' for screening and evaluating the nanocarriers.Read moreRead less