Establishing Design Principles Of Polymers For Intracellular Delivery . Engineered polymers have played a central role in the field of bionanotechnology by enabling targeted nanoscale cell interactions. Progress in the field of intracellular delivery is currently affected by a major bottleneck due to the absence of effective polymers that is applicable across the range of bimolecular cargoes. In essence depending on the type of cargo: DNA, RNA or protien, the polymer needs programmability. The l ....Establishing Design Principles Of Polymers For Intracellular Delivery . Engineered polymers have played a central role in the field of bionanotechnology by enabling targeted nanoscale cell interactions. Progress in the field of intracellular delivery is currently affected by a major bottleneck due to the absence of effective polymers that is applicable across the range of bimolecular cargoes. In essence depending on the type of cargo: DNA, RNA or protien, the polymer needs programmability. The limited tunability of traditional polymers agents makes them unsuitable for this particular application. The multidisciplinary project addresses this significant problem by engineering novel sequences of defined polymer based nanoscale agents to achieve efficient delivery in cells.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210100256
Funder
Australian Research Council
Funding Amount
$415,283.00
Summary
Extracting the hidden structure of glass from particle vibrations. Predicting the rigid behaviour of glass from its disordered, amorphous atomic structure remains a challenge in materials science. This project aims to define an innovative measure of structure based on how constrained each particle is, which can be quantified by measuring the particles’ vibrations. Using this new measure of structure, this project expects to link the microscopic structure of glass to its macroscopic properties v ....Extracting the hidden structure of glass from particle vibrations. Predicting the rigid behaviour of glass from its disordered, amorphous atomic structure remains a challenge in materials science. This project aims to define an innovative measure of structure based on how constrained each particle is, which can be quantified by measuring the particles’ vibrations. Using this new measure of structure, this project expects to link the microscopic structure of glass to its macroscopic properties via computer simulations. Expected outcomes of this project include a new methodology for characterising amorphous materials and an improved understanding of the nature of glass. This should provide significant benefits, such as an increased ability to rationally design amorphous materials with desired properties.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH220100002
Funder
Australian Research Council
Funding Amount
$4,999,700.00
Summary
ARC Research Hub for Fire Resilience Infrastructure, Assets and Safety Advancements (FRIASA) in Urban, Resources, Energy and Renewables Sectors . This Hub aims to develop, manufacture and deploy next generation technologies and solutions that will protect Australia’s critical infrastructure and assets against major natural and man-made fires. The Hub expects to position Australia as a powerhouse of fire readiness by developing end-to-end integrated systems of advanced engineering and digital te ....ARC Research Hub for Fire Resilience Infrastructure, Assets and Safety Advancements (FRIASA) in Urban, Resources, Energy and Renewables Sectors . This Hub aims to develop, manufacture and deploy next generation technologies and solutions that will protect Australia’s critical infrastructure and assets against major natural and man-made fires. The Hub expects to position Australia as a powerhouse of fire readiness by developing end-to-end integrated systems of advanced engineering and digital technologies which will allow industry to improve fire safety training and operations with significant benefits. Expected outcomes include advanced manufacturing capacity for fire resilience and sustainable products, strategic partnerships and commercialisation pathways and opportunities by translating R&D into economic benefits such as jobs and new exports for local and international markets.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100032
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Advanced Multifunctional Electro-Opto-Magneto-Mechanical Analysis Platform. This project aims to build an advanced multi-functional Electro-Opto-Magneto-Mechanical analysis platform for characterizing nanomaterials and micro-/nano-scale devices. This platform expects to provide rich and unique characterization capabilities (electrical, optical, magnetic and mechanical) for hybrid devices with low temperature and high vacuum environment. The expected outcomes include multidisciplinary research co ....Advanced Multifunctional Electro-Opto-Magneto-Mechanical Analysis Platform. This project aims to build an advanced multi-functional Electro-Opto-Magneto-Mechanical analysis platform for characterizing nanomaterials and micro-/nano-scale devices. This platform expects to provide rich and unique characterization capabilities (electrical, optical, magnetic and mechanical) for hybrid devices with low temperature and high vacuum environment. The expected outcomes include multidisciplinary research collaborations and a wide range of next-generation technologies including non-invasive medical instruments, wearable devices, communication, quantum information systems and energy storage solutions. This should enable local design and construction of hybrid devices and advance the growth of local high-technology industries.Read moreRead less
Damage Detection and Quantification using Infrastructure Digital Twins. Structural health monitoring is vital for infrastructure assets management as early detection of structural conditions is key to both safety and ongoing maintenance. This project combines computer vision, vibration tests, finite element modelling and deep learning technologies to develop an efficient structural health monitoring system. Digital twins created from images taken by cameras or UAVs will be correlated through dee ....Damage Detection and Quantification using Infrastructure Digital Twins. Structural health monitoring is vital for infrastructure assets management as early detection of structural conditions is key to both safety and ongoing maintenance. This project combines computer vision, vibration tests, finite element modelling and deep learning technologies to develop an efficient structural health monitoring system. Digital twins created from images taken by cameras or UAVs will be correlated through deep learning with structural conditions and load-carrying capacities obtained from vibration tests and finite element model analysis for efficient structural damage detection and quantification. The project will lead to effective structural health monitoring and enhance structural safety and reduce maintenance costs. Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC210100056
Funder
Australian Research Council
Funding Amount
$3,975,864.00
Summary
ARC Training Centre for Next-Gen Technologies in Biomedical Analysis . The Centre for Next-Gen Technologies in Biomedical Analysis will deliver workforce trained in the development of transformative technologies that will rapidly expand the Australian pharmaceutical, diagnostic and defence sector. The university-industry partnership will increase Australia’s manufacturing capability by fast tracking screening, by integrating 3D printing, advanced sensing, big data analytics, machine learning an ....ARC Training Centre for Next-Gen Technologies in Biomedical Analysis . The Centre for Next-Gen Technologies in Biomedical Analysis will deliver workforce trained in the development of transformative technologies that will rapidly expand the Australian pharmaceutical, diagnostic and defence sector. The university-industry partnership will increase Australia’s manufacturing capability by fast tracking screening, by integrating 3D printing, advanced sensing, big data analytics, machine learning and artificial intelligence for the delivery of optimal solutions in diagnosis, treatment and wellbeing. The centre will deliver training in Industry 4.0 skills which will boost early-stage scale-up and accelerate the sector’s supply chain, which is pivotal for the Australian industries to maintain a competitive edge. Read moreRead less
Understanding and Addressing Everyday Sexisms in Australian Universities. This project aims to improve the ways in which gender-based discrimination is understood and addressed in Australian universities by employing a situated, intersectional, and creative approach to researching everyday sexisms. This project expects to use an innovative approach to generate new knowledge about everyday sexisms at the individual level and across disciplinary and university contexts. Expected outcomes include n ....Understanding and Addressing Everyday Sexisms in Australian Universities. This project aims to improve the ways in which gender-based discrimination is understood and addressed in Australian universities by employing a situated, intersectional, and creative approach to researching everyday sexisms. This project expects to use an innovative approach to generate new knowledge about everyday sexisms at the individual level and across disciplinary and university contexts. Expected outcomes include new gender equity practices that will assist universities to refine current programs, strategies, and policies capable of eliminating gender-based discrimination. This should provide significant benefits for Australian society, including women and gender diverse people working in universities.
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Dating the aboriginal rock art sequence of the Kimberley in north west Australia. This project aims to develop a robust time scale for the known aboriginal rock art sequence in the Kimberley, Western Australia (WA). The project will use new knowledge of complex processes on sandstone surfaces across the north Kimberley, and an innovative combination of four scientific dating methods developed through our earlier work. The project expects to provide a well-dated sequence for Kimberley rock art ba ....Dating the aboriginal rock art sequence of the Kimberley in north west Australia. This project aims to develop a robust time scale for the known aboriginal rock art sequence in the Kimberley, Western Australia (WA). The project will use new knowledge of complex processes on sandstone surfaces across the north Kimberley, and an innovative combination of four scientific dating methods developed through our earlier work. The project expects to provide a well-dated sequence for Kimberley rock art based on replication of results, confirmation across different methods, and a large interdisciplinary data set. The project will allow rigorous analysis of the relationship between dating results and rock art styles that has not previously been possible, and give new insights into Australia’s deep indigenous heritage. This will have a significant impact for future efforts in rock art conservation, and lay a foundation for cultural tourism, with important benefits for the local economy and health of regional indigenous communities.Read moreRead less
Correlative Imaging of Brain Lipids. This project aims to develop imaging tools and protocols for the detection of lipids in brain tissue and cells. This project expects to generate advanced methodologies to display specific lipid classes and their corresponding structures within tissues and cells, with the ability to be detected and correlated with multiple techniques, which represent a currently unavailable capacity. The expected outcomes of this project are improved opportunities to study lip ....Correlative Imaging of Brain Lipids. This project aims to develop imaging tools and protocols for the detection of lipids in brain tissue and cells. This project expects to generate advanced methodologies to display specific lipid classes and their corresponding structures within tissues and cells, with the ability to be detected and correlated with multiple techniques, which represent a currently unavailable capacity. The expected outcomes of this project are improved opportunities to study lipid biology at the cellular and sub-cellular level across a wide range of in vitro and in vivo models. The outcomes of this project should provide significant knowledge to tackle modern societal challenges in healthy ageing, brain pathologies and neurodegenerative diseases.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC210100019
Funder
Australian Research Council
Funding Amount
$4,583,816.00
Summary
ARC Training Centre for Optimal Ageing. The ARC Training Centre for Optimal Ageing aims to address issues identified by older adults as essential for quality of life. With our industry partners, we aim to train the next generation of researchers to understand, detect and improve psychosocial factors that support mental activity, physical health and social connectedness, and embrace advances in artificial intelligence, digital-enriched environments and adaptive workplaces to deliver effective dig ....ARC Training Centre for Optimal Ageing. The ARC Training Centre for Optimal Ageing aims to address issues identified by older adults as essential for quality of life. With our industry partners, we aim to train the next generation of researchers to understand, detect and improve psychosocial factors that support mental activity, physical health and social connectedness, and embrace advances in artificial intelligence, digital-enriched environments and adaptive workplaces to deliver effective digital solutions. By developing new capacity and capability to drive the digital transformation of industries supporting our ageing population, our Centre seeks to deliver economic and social benefits that enable Australians to live enriched, healthy and independent lives as they age.Read moreRead less