Conducting polymer materials. This project aims to understand the optical, electrical and optoelectronic properties of conductive polymers by studying how ions influence the charge transport through the polymeric structure. The discovery of conductive polymers in the 1970s led to smartphone and laptop touch displays and solar cells. These materials promise even more still – but how they operate at the atomic level is not understood. This project could lead to an ability to harness and control th ....Conducting polymer materials. This project aims to understand the optical, electrical and optoelectronic properties of conductive polymers by studying how ions influence the charge transport through the polymeric structure. The discovery of conductive polymers in the 1970s led to smartphone and laptop touch displays and solar cells. These materials promise even more still – but how they operate at the atomic level is not understood. This project could lead to an ability to harness and control these properties for energy storage and wearable displays. These materials’ biological neutrality could lead to drug delivery and sensing applications in the agriculture and healthcare spaces.Read moreRead less
Organic Bionics: Soft Materials to Solve Hard Problems in Neuroengineering. This project aims to combine innovations in organic conductors, nanotechnology, 3D biofabrication and neuroengineering to develop a bioelectronic system capable of wireless neuromodulation with unprecedented stability and precision. This project expects to generate new knowledge regarding the properties of materials that promote optical neuromodulation and new strategies to obtain long-term material stability in biologic ....Organic Bionics: Soft Materials to Solve Hard Problems in Neuroengineering. This project aims to combine innovations in organic conductors, nanotechnology, 3D biofabrication and neuroengineering to develop a bioelectronic system capable of wireless neuromodulation with unprecedented stability and precision. This project expects to generate new knowledge regarding the properties of materials that promote optical neuromodulation and new strategies to obtain long-term material stability in biological environments. The expected outcome is to generate new material design rules to facilitate wireless neuromodulation technologies in biomedical engineering. The project will position Australia as a leader in bionic devices by creating a new 3D bioprinting hub for low-cost fabrication of bioelectronic systems.Read moreRead less
Nanofluid stickiness will transform the Energy and Biotechnology Industries. This project aims to determine how minuscule particles behave on surfaces with different nano-architecture. Modern technologies already use nanodecorated materials to lubricate engines or capture tumour cells. Yet, their potential in applications for sustainable catalysis, gas treatment or water splitting cannot be realised until we understand how nano-objects adsorb to surfaces with features of comparable size. The exp ....Nanofluid stickiness will transform the Energy and Biotechnology Industries. This project aims to determine how minuscule particles behave on surfaces with different nano-architecture. Modern technologies already use nanodecorated materials to lubricate engines or capture tumour cells. Yet, their potential in applications for sustainable catalysis, gas treatment or water splitting cannot be realised until we understand how nano-objects adsorb to surfaces with features of comparable size. The expected outcomes include new methods, models and a workable map of protein adsorption allowing us to 1) create advanced substrates for targeted applications and 2) understand existing phenomenon governed by naturally occurring nanoroughness. It will benefit manufacturing in fields ranging from biology to energy production.Read moreRead less
Next-generation computational models to understand human joints . This project aims to investigate human joint systems through combining state-of-the-art imaging and high-fidelity biomechanical models. The methods developed in this project are expected to generate new ways of studying the dynamic response of musculoskeletal tissues to activity, including how musculoskeletal physiology can adapt to biomechanical stimuli. Expected outcomes include establishing a non-invasive method for characteris ....Next-generation computational models to understand human joints . This project aims to investigate human joint systems through combining state-of-the-art imaging and high-fidelity biomechanical models. The methods developed in this project are expected to generate new ways of studying the dynamic response of musculoskeletal tissues to activity, including how musculoskeletal physiology can adapt to biomechanical stimuli. Expected outcomes include establishing a non-invasive method for characterising whole joint systems. This project will provide significant knowledge gain on the biomechanical regulation of human joints across form, function, dynamics and loading which may help across many facets of society to guide physical activity choices.Read moreRead less
Carbon nanotube based chromatography. This project will reveal new insights into fundamental phenomena of molecular separation processes by carbon nanotubes and underpinning the development of a new generation of microchip separation devices that have the potential to revolutionise chromatographic techniques currently applied in genomics, proteomics, forensics and biotechnology.
Flow structures and transport: predictability and control. Moving flow structures (the boundary of an eddy, the flow interface between two fluids) are crucial in fluid mixing and in the transport of heat, pollutants and nutrients. This project will analyse their roles in improving predictions of spreading extents and rates for geophysical-scale problems, and in controlling transport at the micro-scale. Inaccuracies in currently available numerical diagnostics for transport prediction will be com ....Flow structures and transport: predictability and control. Moving flow structures (the boundary of an eddy, the flow interface between two fluids) are crucial in fluid mixing and in the transport of heat, pollutants and nutrients. This project will analyse their roles in improving predictions of spreading extents and rates for geophysical-scale problems, and in controlling transport at the micro-scale. Inaccuracies in currently available numerical diagnostics for transport prediction will be comprehensively evaluated via comparison with recent exact models. Analytical methods for quantifying transport under unsteady flow protocols will be developed, and used to answer questions on controlling transport in microfluidic applications in conjunction with experimentalists.Read moreRead less
New molecular tools to study the mechanisms of bacterial metal homeostasis. This project aims to provide new insight into how metal ion uptake is regulated. It will precisely measure the cellular concentrations of metal ions, reveal the roles of metal ions in essential cellular processes, and identify the molecular targets of metal toxicity. Metal ions are essential to all forms of life and are used by up to half of all proteins to facilitate cellular chemical processes. The intended outcome of ....New molecular tools to study the mechanisms of bacterial metal homeostasis. This project aims to provide new insight into how metal ion uptake is regulated. It will precisely measure the cellular concentrations of metal ions, reveal the roles of metal ions in essential cellular processes, and identify the molecular targets of metal toxicity. Metal ions are essential to all forms of life and are used by up to half of all proteins to facilitate cellular chemical processes. The intended outcome of the research is to provide new fundamental knowledge of the roles of metal ions in bacterial cells; knowledge that will be key to defining the chemical biology of living systems and will provide information essential to understanding how microbes adapt to changing environments.Read moreRead less
Plasma touches life: advancing plasma technologies for the life sciences. The aim of this project is to develop a mechanistic understanding of how electrically excited gas (plasma) jets deliver reactive oxygen and nitrogen species into tissue, ensuring safety and precision in their use to combat disease. Overcoming barriers in delivery is intended to help realise the full potential of plasma in the life sciences. The project is expected to generate new knowledge across physics, chemistry and bio ....Plasma touches life: advancing plasma technologies for the life sciences. The aim of this project is to develop a mechanistic understanding of how electrically excited gas (plasma) jets deliver reactive oxygen and nitrogen species into tissue, ensuring safety and precision in their use to combat disease. Overcoming barriers in delivery is intended to help realise the full potential of plasma in the life sciences. The project is expected to generate new knowledge across physics, chemistry and biology, leading to new approaches for the future development of plasma technologies. This should provide significant benefits by expanding the human capacity of research in plasma, and in growing the advanced manufacturing of plasma devices for future applications in engineering, biology and health.Read moreRead less
Nanoengineered gradient substrata as a novel approach for understanding infection mechanisms. This project will advance our understanding of how bacteria colonise surfaces and will also inform the development of novel antibacterial coatings and diagnostic tools for device-associated infections, which have a significant impact on patients and are a huge burden to the healthcare system.
New techniques and invariants in low-dimensional topology. The aim of this project is to introduce and apply new methods and invariants in the field of low-dimensional topology by developing parametrised and equivariant enhancements of Seiberg-Witten theory and Floer homology. These new refined invariants, made possible by recent advances in gauge theory, will be more powerful than existing ones, enabling the detection of new exotic phenomena. Expected outcomes include effective means for distin ....New techniques and invariants in low-dimensional topology. The aim of this project is to introduce and apply new methods and invariants in the field of low-dimensional topology by developing parametrised and equivariant enhancements of Seiberg-Witten theory and Floer homology. These new refined invariants, made possible by recent advances in gauge theory, will be more powerful than existing ones, enabling the detection of new exotic phenomena. Expected outcomes include effective means for distinguishing families of spaces, measuring their complexity and new obstructions for their existence. The new invariants and techniques will lead to the resolution of some open problems in low-dimensional topology and enhance Australia's reputation as a world leader in this field.Read moreRead less