Thermodynamics inversion for mineral systems. This project aims to provide a newly developed science approach to the Australian Lithospheric Architecture Magnetotelluric Project (AusLAMP). AusLAMP provides unparalleled geophysical information aimed at unravelling the tectonic history of the Australian continent and its mineral potential. The project will use thermodynamically based geodynamic simulators to jointly analyse and quantify intraplate deformation. This will illuminate the cause of dri ....Thermodynamics inversion for mineral systems. This project aims to provide a newly developed science approach to the Australian Lithospheric Architecture Magnetotelluric Project (AusLAMP). AusLAMP provides unparalleled geophysical information aimed at unravelling the tectonic history of the Australian continent and its mineral potential. The project will use thermodynamically based geodynamic simulators to jointly analyse and quantify intraplate deformation. This will illuminate the cause of driving fluid flow thorough the lithosphere, mineralisation phenomena, their datasets and geometries, and dynamic aspects of the processes driving mineral systems.Read moreRead less
Low-Cost Multiple Pencil-Beam Lens Antenna System. The project aims to develop a new multiple pencil beam antenna system, taking advantage of CIs' preliminary inventions in lens antennas, 3D printed antennas and arrays, and antenna feeding networks. A dual-polarised antenna array architecture will enhance the sensing quality and resolution of our partner organisation's cleaning robot. It will enable the robot to recognise human presence and movement in low-light conditions for rapid and safe dis ....Low-Cost Multiple Pencil-Beam Lens Antenna System. The project aims to develop a new multiple pencil beam antenna system, taking advantage of CIs' preliminary inventions in lens antennas, 3D printed antennas and arrays, and antenna feeding networks. A dual-polarised antenna array architecture will enhance the sensing quality and resolution of our partner organisation's cleaning robot. It will enable the robot to recognise human presence and movement in low-light conditions for rapid and safe disinfection of public spaces. The project will have an immediate socio-economic impact on local businesses and communities. The outcomes of the project will create safer public environments for people living and working in Australia, and boost economic recovery in the post-pandemic period.Read moreRead less
Engineering defect-intensive ozonation catalysts to degrade micropollutants. This project aims to engineer unique particles containing defect-intensive surfaces which are designed to accelerate the catalytic ozonation of waters contaminated with pharmaceuticals and other recalcitrant pollutants. This will enable timely treatment of industrial waste water as well as sewerage treatment plant effluents using simple and cheap catalyst materials. Wet- and flame-based particle fabrication technologies ....Engineering defect-intensive ozonation catalysts to degrade micropollutants. This project aims to engineer unique particles containing defect-intensive surfaces which are designed to accelerate the catalytic ozonation of waters contaminated with pharmaceuticals and other recalcitrant pollutants. This will enable timely treatment of industrial waste water as well as sewerage treatment plant effluents using simple and cheap catalyst materials. Wet- and flame-based particle fabrication technologies paired with unique post-synthesis treatment strategies, including either a coupled hydrogenation-illumination approach or plasma exposure, will be implemented for defect manipulation so as to produce new cheaper, stable, and higher-performing catalysts for activating ozone to treat water containing pharmaceutical and endocrine disrupting micro-pollutants under different process conditions.Read moreRead less
Wideband Silicon-Based Radio-Frequency Front-End Module for 5G New Radio . The project aims to advance knowledge in radio-frequency integrated circuit design in low-cost silicon technologies, particularly power amplifiers design with enhanced energy efficiency at output power back-off levels. The intended outcome of this project will be a wideband RF front-end module with beam steering capability that can cover the 24-50 GHz spectrum band. This will ultimately enable the creation of a low-cost a ....Wideband Silicon-Based Radio-Frequency Front-End Module for 5G New Radio . The project aims to advance knowledge in radio-frequency integrated circuit design in low-cost silicon technologies, particularly power amplifiers design with enhanced energy efficiency at output power back-off levels. The intended outcome of this project will be a wideband RF front-end module with beam steering capability that can cover the 24-50 GHz spectrum band. This will ultimately enable the creation of a low-cost and energy-efficient 5G millimetre-wave network that could potentially trigger the development of ultra-reliable low latency communications, which is critical for emerging intelligent transportation systems and will maintain Australia’s leadership position in the development of break-through wireless technology.Read moreRead less
Low-Cost Wireless Transmitter with Compact Package for Industrial Sensing . This project aims to provide a solid foundation for silicon-based transmitter design with beam-steering capability operating beyond 100 GHz. The project expects to advance knowledge in low-cost radio-frequency integrated circuit design with miniaturised packaging technology for use in industrial sensing. Expected outcomes of this project include a prototype consisting of a miniaturised 140-GHz phased-array transmitter wi ....Low-Cost Wireless Transmitter with Compact Package for Industrial Sensing . This project aims to provide a solid foundation for silicon-based transmitter design with beam-steering capability operating beyond 100 GHz. The project expects to advance knowledge in low-cost radio-frequency integrated circuit design with miniaturised packaging technology for use in industrial sensing. Expected outcomes of this project include a prototype consisting of a miniaturised 140-GHz phased-array transmitter with packaged antenna arrays, along with a developed selection guideline to choose the "best" silicon-based technology node for cost-effective design. This should provide benefits for organisations working on wireless sensing technologies and lead to new ways of using these technologies for a variety of emerging applications.Read moreRead less
Microfluidic platforms for studying foam cell formation in vessels . This project aims to create technology platforms, utilising microfluidics and machine learning, to study the fundamental biological processes underlying the accumulation of immune cells underneath the vessel wall, which is known as foam cell formation. This project expects to deliver technologies, which facilitate mimicking and analysis of the complex dynamics of the human vessels in a more accurate, time- and cost-effective ma ....Microfluidic platforms for studying foam cell formation in vessels . This project aims to create technology platforms, utilising microfluidics and machine learning, to study the fundamental biological processes underlying the accumulation of immune cells underneath the vessel wall, which is known as foam cell formation. This project expects to deliver technologies, which facilitate mimicking and analysis of the complex dynamics of the human vessels in a more accurate, time- and cost-effective manner. The expected outcome will be cutting-edge tools and techniques to better understand the fundamental biological mechanisms driving foam cell formation. This should facilitate the development of future cardiovascular drug discovery technologies, which would benefit the biotechnology and pharmaceutical industries.Read moreRead less
Precise, Cytosolic Dendrimer Delivery Systems. This project aims to use precisely targeted dendrimer technology to improve the delivery of poorly permeable molecules to their subcellular sites of action. Our cutting edge approach combines innovative phage screening techniques and advanced dendrimer synthesis. The outcomes of this proposal will be: 1) a targeting system that is manufacturable at scale and reasonable cost, 2) a dendrimer delivery system that is rapidly internalised into specifc ta ....Precise, Cytosolic Dendrimer Delivery Systems. This project aims to use precisely targeted dendrimer technology to improve the delivery of poorly permeable molecules to their subcellular sites of action. Our cutting edge approach combines innovative phage screening techniques and advanced dendrimer synthesis. The outcomes of this proposal will be: 1) a targeting system that is manufacturable at scale and reasonable cost, 2) a dendrimer delivery system that is rapidly internalised into specifc target cells and 3) bio-responsive dendrimers that promote delivery of their cargo into the cytosol. This work will strengthen a highly successful collaboration between the Australian biotech company Starpharma and Monash University, to design the next generation of nanomaterials delivery systems.Read moreRead less
Next generation closed-loop brain-machine interfaces . Our partners Carbon Cybernetics have developed high-density neural recording and stimulation arrays that employ fine carbon fibres as the electrode material. The aim of the project is to exploit the properties of these materials to develop miniature implantable devices that are able to achieve long-term, closed-loop, high-resolution recording and stimulation within the brain. We aim to demonstrate an advanced algorithm for control of neural ....Next generation closed-loop brain-machine interfaces . Our partners Carbon Cybernetics have developed high-density neural recording and stimulation arrays that employ fine carbon fibres as the electrode material. The aim of the project is to exploit the properties of these materials to develop miniature implantable devices that are able to achieve long-term, closed-loop, high-resolution recording and stimulation within the brain. We aim to demonstrate an advanced algorithm for control of neural function. Devices that interface directly with the brain are increasingly important in neuroscience to understand how the brain processes information and creates memories and self awareness and are critically important to the development of technologies that interface electronics with the human body. Read moreRead less
Development of a market relevant DNA nano-vaccine platform. DNA vaccine technology can potentially provide a rapid response to existing or new pathogens, but its market success has been limited. By addressing key scientific and technical challenges, this project aims to develop a new and cost-effective DNA nanovaccine platform using a multiscale engineering approach. It is anticipated that novel nanoparticles for DNA delivery and an end-user-driven DNA vaccine technology with enhanced immunogeni ....Development of a market relevant DNA nano-vaccine platform. DNA vaccine technology can potentially provide a rapid response to existing or new pathogens, but its market success has been limited. By addressing key scientific and technical challenges, this project aims to develop a new and cost-effective DNA nanovaccine platform using a multiscale engineering approach. It is anticipated that novel nanoparticles for DNA delivery and an end-user-driven DNA vaccine technology with enhanced immunogenicity, stability and safety will be generated. Expected outcomes include new knowledge in nanomaterial science and a market ready technology platform, improving Australia’s capabilities in nanobiotechnology and vaccine development, as well as delivering a new value-added product for the Industry Partner. Read moreRead less
Deadly Futures:Enabling Indigenous Children’s Literacy, Numeracy, Wellbeing. This project aims to test the effectiveness of new literacy, numeracy and wellbeing interventions using powerful interdisciplinary approaches. The project expects to generate new knowledge about enabling Indigenous students to have deadly futures by enhancing literacy, numeracy and wellbeing, capitalising on research-derived interventions and the wisdom of Indigenous communities. Expected outcomes include salient interv ....Deadly Futures:Enabling Indigenous Children’s Literacy, Numeracy, Wellbeing. This project aims to test the effectiveness of new literacy, numeracy and wellbeing interventions using powerful interdisciplinary approaches. The project expects to generate new knowledge about enabling Indigenous students to have deadly futures by enhancing literacy, numeracy and wellbeing, capitalising on research-derived interventions and the wisdom of Indigenous communities. Expected outcomes include salient intervention and advances in Indigenous education. Benefits encompass identifying effective intervention and drivers that enhance Indigenous students’ literacy, numeracy, wellbeing, and adaptive motivation, and working effectively in genuine partnership with Indigenous community to address a community-identified need.Read moreRead less