Three dimensional nano-lithography: combined electron and ion beam fabrication. By adding one more dimension to a planar (hence two dimensional - 2D) lithography, it will become possible to structure and texture materials in three dimensions (3D) by combining electron beam lithography (2D) and ion beam milling (3D) with the highest precision of several nanometres. This will open new applications in photonics and sensing.
Bodies in space. By investigating how a change in shape of the human body can produce a change in spatial orientation, the project will bring a fundamental advance of knowledge in the intersection of applied mathematics, sports science and mechanical engineering. These knowledge advances will lead to a novel theory regarding the control of the aerial dynamics of athletes, specifically springboard and platform divers. When applied in collaboration with world class Australian athletes, this theory ....Bodies in space. By investigating how a change in shape of the human body can produce a change in spatial orientation, the project will bring a fundamental advance of knowledge in the intersection of applied mathematics, sports science and mechanical engineering. These knowledge advances will lead to a novel theory regarding the control of the aerial dynamics of athletes, specifically springboard and platform divers. When applied in collaboration with world class Australian athletes, this theory will result in innovative platform and springboard diving techniques and improved performance. The reach of new insights generated by this work extends to many other fields, including robotics, spacecraft dynamics and nano technology.Read moreRead less
Practical model-based control for low emission and low cost diesel engines. Practical model-based control for low emission and low cost diesel engines. This project aims to develop and implement robust multivariable model predictive control algorithms for low emission and low cost diesel engines that reduce calibration effort. Legislative and increasing consumer requirements demand better control approaches than have been deployed in production vehicles to date, and motivate the use of model bas ....Practical model-based control for low emission and low cost diesel engines. Practical model-based control for low emission and low cost diesel engines. This project aims to develop and implement robust multivariable model predictive control algorithms for low emission and low cost diesel engines that reduce calibration effort. Legislative and increasing consumer requirements demand better control approaches than have been deployed in production vehicles to date, and motivate the use of model based techniques to meet performance and emissions specifications. However, current model-based controllers amplify the calibration effort and increase development costs as the tuning parameters are not related to time domain specifications. The anticipated outcome is new model based control architectures that improve diesel engine operation and reduce its calibration effort and cost.Read moreRead less
Engineering drug transportation behaviour in polymeric gel systems. In collaboration with Seagull Technologies, this project aims to engineer, study and mathematically model ultrasound-assisted biomacromolecule transport behaviour within polymeric gel systems, which may be useful in new drug delivery methods. The intended outcome is a novel set of polymeric gel systems, which can reversibly bind a wide variety of drugs (small molecules, nucleic acid based drugs, proteins), in which drug release ....Engineering drug transportation behaviour in polymeric gel systems. In collaboration with Seagull Technologies, this project aims to engineer, study and mathematically model ultrasound-assisted biomacromolecule transport behaviour within polymeric gel systems, which may be useful in new drug delivery methods. The intended outcome is a novel set of polymeric gel systems, which can reversibly bind a wide variety of drugs (small molecules, nucleic acid based drugs, proteins), in which drug release is triggered by an electric potential and drug transport is controlled by means of sonophoresis. The main advantage of drug delivery via sonophoresis is elimination of risks associated with injections such as infection and damage to local tissue, and elimination of patient discomfort, pain and fear.Read moreRead less
Wideband Silicon-Based Radio-Frequency Front-End Module for 5G New Radio . The project aims to advance knowledge in radio-frequency integrated circuit design in low-cost silicon technologies, particularly power amplifiers design with enhanced energy efficiency at output power back-off levels. The intended outcome of this project will be a wideband RF front-end module with beam steering capability that can cover the 24-50 GHz spectrum band. This will ultimately enable the creation of a low-cost a ....Wideband Silicon-Based Radio-Frequency Front-End Module for 5G New Radio . The project aims to advance knowledge in radio-frequency integrated circuit design in low-cost silicon technologies, particularly power amplifiers design with enhanced energy efficiency at output power back-off levels. The intended outcome of this project will be a wideband RF front-end module with beam steering capability that can cover the 24-50 GHz spectrum band. This will ultimately enable the creation of a low-cost and energy-efficient 5G millimetre-wave network that could potentially trigger the development of ultra-reliable low latency communications, which is critical for emerging intelligent transportation systems and will maintain Australia’s leadership position in the development of break-through wireless technology.Read moreRead less
Low-Cost Wireless Transmitter with Compact Package for Industrial Sensing . This project aims to provide a solid foundation for silicon-based transmitter design with beam-steering capability operating beyond 100 GHz. The project expects to advance knowledge in low-cost radio-frequency integrated circuit design with miniaturised packaging technology for use in industrial sensing. Expected outcomes of this project include a prototype consisting of a miniaturised 140-GHz phased-array transmitter wi ....Low-Cost Wireless Transmitter with Compact Package for Industrial Sensing . This project aims to provide a solid foundation for silicon-based transmitter design with beam-steering capability operating beyond 100 GHz. The project expects to advance knowledge in low-cost radio-frequency integrated circuit design with miniaturised packaging technology for use in industrial sensing. Expected outcomes of this project include a prototype consisting of a miniaturised 140-GHz phased-array transmitter with packaged antenna arrays, along with a developed selection guideline to choose the "best" silicon-based technology node for cost-effective design. This should provide benefits for organisations working on wireless sensing technologies and lead to new ways of using these technologies for a variety of emerging applications.Read moreRead less
Microfluidic platforms for studying foam cell formation in vessels . This project aims to create technology platforms, utilising microfluidics and machine learning, to study the fundamental biological processes underlying the accumulation of immune cells underneath the vessel wall, which is known as foam cell formation. This project expects to deliver technologies, which facilitate mimicking and analysis of the complex dynamics of the human vessels in a more accurate, time- and cost-effective ma ....Microfluidic platforms for studying foam cell formation in vessels . This project aims to create technology platforms, utilising microfluidics and machine learning, to study the fundamental biological processes underlying the accumulation of immune cells underneath the vessel wall, which is known as foam cell formation. This project expects to deliver technologies, which facilitate mimicking and analysis of the complex dynamics of the human vessels in a more accurate, time- and cost-effective manner. The expected outcome will be cutting-edge tools and techniques to better understand the fundamental biological mechanisms driving foam cell formation. This should facilitate the development of future cardiovascular drug discovery technologies, which would benefit the biotechnology and pharmaceutical industries.Read moreRead less
Precise, Cytosolic Dendrimer Delivery Systems. This project aims to use precisely targeted dendrimer technology to improve the delivery of poorly permeable molecules to their subcellular sites of action. Our cutting edge approach combines innovative phage screening techniques and advanced dendrimer synthesis. The outcomes of this proposal will be: 1) a targeting system that is manufacturable at scale and reasonable cost, 2) a dendrimer delivery system that is rapidly internalised into specifc ta ....Precise, Cytosolic Dendrimer Delivery Systems. This project aims to use precisely targeted dendrimer technology to improve the delivery of poorly permeable molecules to their subcellular sites of action. Our cutting edge approach combines innovative phage screening techniques and advanced dendrimer synthesis. The outcomes of this proposal will be: 1) a targeting system that is manufacturable at scale and reasonable cost, 2) a dendrimer delivery system that is rapidly internalised into specifc target cells and 3) bio-responsive dendrimers that promote delivery of their cargo into the cytosol. This work will strengthen a highly successful collaboration between the Australian biotech company Starpharma and Monash University, to design the next generation of nanomaterials delivery systems.Read moreRead less
Next generation closed-loop brain-machine interfaces . Our partners Carbon Cybernetics have developed high-density neural recording and stimulation arrays that employ fine carbon fibres as the electrode material. The aim of the project is to exploit the properties of these materials to develop miniature implantable devices that are able to achieve long-term, closed-loop, high-resolution recording and stimulation within the brain. We aim to demonstrate an advanced algorithm for control of neural ....Next generation closed-loop brain-machine interfaces . Our partners Carbon Cybernetics have developed high-density neural recording and stimulation arrays that employ fine carbon fibres as the electrode material. The aim of the project is to exploit the properties of these materials to develop miniature implantable devices that are able to achieve long-term, closed-loop, high-resolution recording and stimulation within the brain. We aim to demonstrate an advanced algorithm for control of neural function. Devices that interface directly with the brain are increasingly important in neuroscience to understand how the brain processes information and creates memories and self awareness and are critically important to the development of technologies that interface electronics with the human body. Read moreRead less
Automating real-time feedback in virtual reality training through data mining. This project will use data mining techniques to develop a real-time feedback system that can be used in virtual reality training environments. This system will not only improve trainees' learning, it will also lead to more efficient use of virtual reality training in industries such as aviation, aerospace, mining, health and emergency services.