Functional MRI And MR Spectroscopic Studies Of Penicillin Induced And Kindled Sheep Models Of Epilepsy
Funder
National Health and Medical Research Council
Funding Amount
$311,244.00
Summary
Epilepsy is one of the most common neurological disorders, affecting 1-2% of the population. Many epilepsy patients do not respond to drug therapy and their only hope for seizure control is surgical removal of the part of the brain responsible for their seizures. Successful surgery is very much dependent on the ability to exactly localize the seizure focus and this is often not possible using the imaging techniques currently available. Functional magnetic resonance imaging (fMRI) is a new techni ....Epilepsy is one of the most common neurological disorders, affecting 1-2% of the population. Many epilepsy patients do not respond to drug therapy and their only hope for seizure control is surgical removal of the part of the brain responsible for their seizures. Successful surgery is very much dependent on the ability to exactly localize the seizure focus and this is often not possible using the imaging techniques currently available. Functional magnetic resonance imaging (fMRI) is a new technique which may improve our ability to localize the seizure focus from which seizures arise, if the brain can be imaged at, or near, the time of a seizure. MR spectroscopy (MRS) enables us to detect metabolic changes in the brain which may persist at the site where seizures have begun for up to 30 minutes after the seizure. The aim of our research is to obtain a greater understanding of the changes detected with these MR modalities so that we can learn to apply these techniques to human sufferers of epilepsy. Ultimately it may help enable previously incurable epilepsy patients to undergo successful surgery and live normal lives.Read moreRead less
I am a cardiovascular physiologist investigating the origin of the large increases in cardiac and renal sympathetic nerve activity in heart failure,the causes of acute renal failure in septic shock and mechanisms to reduce myocardial ischaemia-reperfusion
The Victorian Centre For Applied Biostatistics (VCAB): Building Core Methodological Capacity For Population Health
Funder
National Health and Medical Research Council
Funding Amount
$2,497,184.00
Summary
Biostatistics is the scientific discipline that focusses on the methods used to design and analyse research studies on human health. Doctors and other researchers conduct increasingly complex studies to identify best approaches for the prevention and treatment of disease, and these studies must be underpinned by sound biostatistical methods. This Centre will develop a critical mass of expertise in this under-resourced area around a program of methodological research, translation and training.
The Centre for Research Excellence in Discovering Indigenous Strategies to improve Cancer Outcomes Via Engagement, Research Translation and Training (DISCOVER-TT) aims to reduce the marked disparities in diagnosis, treatment and survival for Indigenous Australians with cancer. DISCOVER-TT’s co-ordinated, collaborative, Indigenous-led research program will feature extensive stakeholder engagement to ensure its work is relevant and applicable, and will enhance research capacity by developing early ....The Centre for Research Excellence in Discovering Indigenous Strategies to improve Cancer Outcomes Via Engagement, Research Translation and Training (DISCOVER-TT) aims to reduce the marked disparities in diagnosis, treatment and survival for Indigenous Australians with cancer. DISCOVER-TT’s co-ordinated, collaborative, Indigenous-led research program will feature extensive stakeholder engagement to ensure its work is relevant and applicable, and will enhance research capacity by developing early-career researchers.Read moreRead less
An Evaluation Of Trust In A Primary Health Care System
Funder
National Health and Medical Research Council
Funding Amount
$135,550.00
Summary
Trust is a critical issue in the relationships between organisations that need to work together to achieve integrated services for consumers. As organisational representatives get to know one another trust may develop permitting a greater degree of collaboration. In Victoria, the Primary Care Partnerships Strategy process aims to strengthen the relationships between agencies in alocal areas to improve collaboration and achieve services that operate in an integrated way in the provision of servic ....Trust is a critical issue in the relationships between organisations that need to work together to achieve integrated services for consumers. As organisational representatives get to know one another trust may develop permitting a greater degree of collaboration. In Victoria, the Primary Care Partnerships Strategy process aims to strengthen the relationships between agencies in alocal areas to improve collaboration and achieve services that operate in an integrated way in the provision of services to consumers. It is about strengthening the system of care. The aim of this study is to understand how people within a primary care system build and maintain relationships of trust between individuals and between organisations. Individuals will be interviewed to learn how they experience trust and related issues, documents will be analysed to learn about the policy and organisational environments of trust relationships, and the Trust Evaluation Scale used to measure the factors associated with trust over a two year period. The outcomes of this study will be an understanding of how organisations establish the relationships that allow them to collaborate effectively. In particular it will help us understand how they can be encouraged to share the same protocols and procedures, to share information, and become more skilful at managing organisational differences, and it will provide a deeper understanding of relationships between primary health care organisations and the strategies that can help individuals and organisations create trust and collaborate.Read moreRead less