REDucing Delays In Aneurysmal Subarachnoid Haemorrhage: The REDDISH Study
Funder
National Health and Medical Research Council
Funding Amount
$436,022.00
Summary
Aneurysmal subarachnoid haemorrhage (aSAH) is a rare form of stroke that kills at least 30% of sufferers within 1 month. Outcome can be improved through quickly receiving medical care but many people do not and this likely contributes to the poor outcomes. The REDucing Delays In Subarachnoid Haemorrhage (REDDISH) study will look at cases of aSAH across Tasmanian and Victoria so that we can understand the factors that contribute to delays in treatment and ultimately improve outcomes.
Outcomes After Serious Injury: What Is The Recovery Trajectory And How Do The Priorities For Treatment And Disability Services Change Over Time?
Funder
National Health and Medical Research Council
Funding Amount
$766,630.00
Summary
Traumatic injury is a significant contributor to global disease burden, with serious injury commonly resulting in disability and profound costs to the individual, family and society. This population-based project will describe the long term consequences of injury and recovery experiences of more than 2500 seriously injured patients. This longitudinal study will use quantitative and qualitative data to provide a comprehensive overview of patient outcomes and experiences in the first 5-years after ....Traumatic injury is a significant contributor to global disease burden, with serious injury commonly resulting in disability and profound costs to the individual, family and society. This population-based project will describe the long term consequences of injury and recovery experiences of more than 2500 seriously injured patients. This longitudinal study will use quantitative and qualitative data to provide a comprehensive overview of patient outcomes and experiences in the first 5-years after injury.Read moreRead less
Ensuring The Utility And Sustainability Of Tissue Banks: Supporting Translational Research In Australia Through Informed Regulation And Community Engagement.
Funder
National Health and Medical Research Council
Funding Amount
$481,885.00
Summary
Tissue banks provide a critical resource for translational research into the causes and treatment of many diseases affecting children and adults, such as cancer.Their success and contribution to medical research depends on addressing the many unresolved and emerging challenges that impact their work. This is the first national empirical study engaging the Australian research community, legal experts tissue donors and the public about the challenges to tissue banks to inform ethico legal regulati ....Tissue banks provide a critical resource for translational research into the causes and treatment of many diseases affecting children and adults, such as cancer.Their success and contribution to medical research depends on addressing the many unresolved and emerging challenges that impact their work. This is the first national empirical study engaging the Australian research community, legal experts tissue donors and the public about the challenges to tissue banks to inform ethico legal regulation and deliver better health care systems.Read moreRead less
STARRT-AKI: STandard Versus Accelerated Initiation Of Renal Replacement Therapy In Acute Kidney Injury
Funder
National Health and Medical Research Council
Funding Amount
$2,112,447.00
Summary
Acute kidney failure is increasing globally and there are no treatments proven to improve patient outcomes. The STARRT-AKI Study will, as part of an international collaboration, examine the effect upon patient survival of the timing of dialysis initiation in patients with acute kidney failure who are critically ill in intensive care units.
Social Media To Enhance Indigenous Tobacco Control
Funder
National Health and Medical Research Council
Funding Amount
$922,680.00
Summary
Smoking prevalence among Aboriginal and Torres Strait Islander people is more than twice as high as the overall Australian population, and smoking is the leading cause of mortality and morbidity of Indigenous Australians. Accelerating the decline in smoking prevalence is an urgent priority to Close The Gap in health outcomes. The aim of this project is to understand how social media can be harnessed to enhance the impact of proven tobacco control strategies among Indigenous Australians.
Evaluating Cancer Screening: Context, Evidence, Values And Ethics
Funder
National Health and Medical Research Council
Funding Amount
$572,460.00
Summary
The research and clinical communities are divided over whether certain forms of cancer screening do more harm than good. This project asks: What is the right thing to do about cancer screening now? Using robust qualitative methodologies, we will study real cases of cancer screening and analyse their ethical implications. Drawing on this data and analysis, we will produce tools to help policy-makers, consumers and professionals make good decisions about cancer screening in future.
Short Duration Hypothermia To Prevent Subsequent Intracranial Pressure Rise.
Funder
National Health and Medical Research Council
Funding Amount
$436,453.00
Summary
Elevated brain pressure after stroke or other forms of brain injury can cause further injury and death. Body cooling to 32-33 C (hypothermia) for 12-24 hours saves lives after some forms of brain injury, but may have major side effects. We found that 2 hours hypothermia has a long-lasting effect preventing pressure elevation. We will determine the best temperature and duration of hypothermia in a stroke model and use imaging to confirm findings in patients, with a view to later human trials.
Optimising Men’s Uptake Of FIT Screening For Bowel Cancer: A Population Based Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$552,522.00
Summary
Men are more likely to die from bowel cancer but are not participating in the National Bowel Cancer Screening program to the same extent as women. The research group has devised simple messages that their previous research shows encourages men to use the screening kit. The team will compare the use of kits among men who get the Government’s usual invitations, with a group who receive invitations with the messages for men.
The Ludwig Institute is adopting a two prong approach in the fight against cancer. Ludwig scientists are developing improved and sensitive scanning methods to aid in the conduct of field trials of new anti-cancer antibodies. In addition, they are also developing new targeted anti-cancer antibodies with improved properties that have the ability to bind to tumours while sparing normal tissues. These drugs can either attack the cancer directly or be used to carry drugs to the target thereby shrinki ....The Ludwig Institute is adopting a two prong approach in the fight against cancer. Ludwig scientists are developing improved and sensitive scanning methods to aid in the conduct of field trials of new anti-cancer antibodies. In addition, they are also developing new targeted anti-cancer antibodies with improved properties that have the ability to bind to tumours while sparing normal tissues. These drugs can either attack the cancer directly or be used to carry drugs to the target thereby shrinking the tumour.Read moreRead less
IV Iron For Treatment Of Anaemia Before Cardiac Surgery (ITACS Trial)
Funder
National Health and Medical Research Council
Funding Amount
$2,285,290.00
Summary
Our aim is to evaluate intravenous iron to treat anaemia in 1000 patients waiting for their cardiac surgery. This could reduce the risks of the operation and enable patients to recover faster and can go home earlier.