Intracortical inhibition evaluated by paired-pulse TMS during choice and simple reaction time tasks. The research will investigate the neurophysiological processes responsible for the selection and initiation of movement in response to an external stimulus. Slowness in the initiation and execution of movement is a common feature of 'neurological aging', neurodegenerative disease, and brain injury. Understanding the brain mechanisms involved in response selection and movement initiation will pro ....Intracortical inhibition evaluated by paired-pulse TMS during choice and simple reaction time tasks. The research will investigate the neurophysiological processes responsible for the selection and initiation of movement in response to an external stimulus. Slowness in the initiation and execution of movement is a common feature of 'neurological aging', neurodegenerative disease, and brain injury. Understanding the brain mechanisms involved in response selection and movement initiation will provide information for the development of specific intervention techniques to improve motor function in these groups.Read moreRead less
Neural correlates of performance trade-offs and interference in dual-task performance. Our daily lives are characterised by our ability to produce and sustain a wide range of different movement patterns and to deliberately change patterns as the situation demands. In this project we seek to understand the relationship between brain processes, attentional demands, and the control and learning of coordinated behaviour. A further aim will be to examine how this relationship may be altered as a re ....Neural correlates of performance trade-offs and interference in dual-task performance. Our daily lives are characterised by our ability to produce and sustain a wide range of different movement patterns and to deliberately change patterns as the situation demands. In this project we seek to understand the relationship between brain processes, attentional demands, and the control and learning of coordinated behaviour. A further aim will be to examine how this relationship may be altered as a result of aging, degenerative disease, or brain damage. This research will provide a foundation upon which rehabilitation strategies can be developed for the movement impaired.Read moreRead less
Facilitatory and inhibitory mechanisms during interlimb coordination in young and older adults. The project seeks to understand how people coordinate their limbs and the factors which limit and enhance this capacity. This is of critical importance because coordination is a dominant deficit in aging and in patients suffering brain insult and neurodegenerative diseases. Disruption of this capacity compromises individual work productivity, mobility and independence. Proficient motor functioning is ....Facilitatory and inhibitory mechanisms during interlimb coordination in young and older adults. The project seeks to understand how people coordinate their limbs and the factors which limit and enhance this capacity. This is of critical importance because coordination is a dominant deficit in aging and in patients suffering brain insult and neurodegenerative diseases. Disruption of this capacity compromises individual work productivity, mobility and independence. Proficient motor functioning is an important lifestyle factor as humans age and deficits in coordinated muscle activity will increase the risk of falls which are the leading cause of injury in elderly adults. Identification of changes in brain processes involved in interlimb coordination will allow for the development of strategies to improve motor functions in the aged.Read moreRead less
Interlimb coordination dynamics in stroke. Everyday we use our limbs in a coordinated manner. However, for a person who has suffered a stroke resulting in weakness on one side of the body even the simplest interlimb coordination tasks are difficult to perform. This project will examine interlimb coordination in persons who have suffered a stroke and explore whether the coupling between limbs can be exploited to promote fuctional recovery of an impaired limb. In particular, the research seeks to ....Interlimb coordination dynamics in stroke. Everyday we use our limbs in a coordinated manner. However, for a person who has suffered a stroke resulting in weakness on one side of the body even the simplest interlimb coordination tasks are difficult to perform. This project will examine interlimb coordination in persons who have suffered a stroke and explore whether the coupling between limbs can be exploited to promote fuctional recovery of an impaired limb. In particular, the research seeks to identify the critical components underlying the effectiveness of an intervention involving the pratice of actions bilaterally and simultaneously.Read moreRead less
An investigation of limb dynamics as a constraint on human motor learning. Everyday we use our limbs to interact with a variety of objects. These objects have various mechanical characteristics (dynamics), which require the human motor system to provide appropriate control. This project seeks to understand how the brain, in both normal and disease states, learns new limb dynamics as we interact with a novel mechanical environmental. Repetitive brain stimulation will be used to selectively block ....An investigation of limb dynamics as a constraint on human motor learning. Everyday we use our limbs to interact with a variety of objects. These objects have various mechanical characteristics (dynamics), which require the human motor system to provide appropriate control. This project seeks to understand how the brain, in both normal and disease states, learns new limb dynamics as we interact with a novel mechanical environmental. Repetitive brain stimulation will be used to selectively block the contribution of various cortical regions during the learning of a new motor skill and later, the recall of that skill. This will allow us to determine definitively which areas are critical to motor skill acquisition.Read moreRead less
The genetic and diagnostic relationship between motor control and Attention Deficit Hyperactivity Disorder. Children with Attention Deficit Hyperactivity Disorder (ADHD) often have comorbid Developmental Coordination Disorder (DCD). This project will utilise the expertise of leading researchers in Australia and the Netherlands to investigate the genetic and diagnostic relationship between these two disorders utilising a large sample of twins and their siblings. We will examine the neuropsych ....The genetic and diagnostic relationship between motor control and Attention Deficit Hyperactivity Disorder. Children with Attention Deficit Hyperactivity Disorder (ADHD) often have comorbid Developmental Coordination Disorder (DCD). This project will utilise the expertise of leading researchers in Australia and the Netherlands to investigate the genetic and diagnostic relationship between these two disorders utilising a large sample of twins and their siblings. We will examine the neuropsychological functioning in these groups of children in order to gain a better understanding of their genetic relationship. These findings will provide insight into the current DSM-IV classification of these disorders compared with other models used to investigate the relationship between poor motor coordination and ADHD.Read moreRead less
Stochastic, Neurally-Plausible Models for Selective Attention and Decision Making. An understanding of the basic cognitive processes involved in attention and decision making is the goal of international research effort in a number of disciplines. The benefits expected from such understanding include improvements in the diagnosis and treatment of a variety of cognitive deficits and improved occupational safety and efficiency in settings involving interaction with complex systems, such air traffi ....Stochastic, Neurally-Plausible Models for Selective Attention and Decision Making. An understanding of the basic cognitive processes involved in attention and decision making is the goal of international research effort in a number of disciplines. The benefits expected from such understanding include improvements in the diagnosis and treatment of a variety of cognitive deficits and improved occupational safety and efficiency in settings involving interaction with complex systems, such air traffic control, airline cockpits, motor vehicles, and process management. By developing mathematical models of these processes and the neural mechanisms that underlie them, this project will contribute to this understanding. It will also provide international postdoctoral opportunties for Australian-trained Ph.D. graduates.Read moreRead less
The mind's nose: Evocation, representation and similarity of imaginary and real odours. The food industry is a key sector in the Australian economy, accounting for 26.6 Billion Dollars in exports in 2001/2. Every year substantial sums are spent advertising, developing and testing new products, with notoriously high failure rates. Arguably both advertising and development depend, to some degree, on the ability of people to imagine the flavour and smell of these products. This project should id ....The mind's nose: Evocation, representation and similarity of imaginary and real odours. The food industry is a key sector in the Australian economy, accounting for 26.6 Billion Dollars in exports in 2001/2. Every year substantial sums are spent advertising, developing and testing new products, with notoriously high failure rates. Arguably both advertising and development depend, to some degree, on the ability of people to imagine the flavour and smell of these products. This project should identify procedures which enhance peoples ability to do this. Such findings should enable advertisers to design advertisements that are better able to induce imaginary aromas in their audience and enhance the training of food product developers, so they too can better imagine and conceptualise new food products.Read moreRead less
Working Memory: The Binding of Spatial and Nonspatial Features in the Retention of Visual and Auditory Information. By advancing the understanding of how integrated representations are retained in memory for the features of visual objects and the features of sounds, the research will provide new theoretical insights as well as new methods for investigating several forms of psychopathology. Deficits in feature binding have been argued to be implicated in autism, in the auditory hallucinations exp ....Working Memory: The Binding of Spatial and Nonspatial Features in the Retention of Visual and Auditory Information. By advancing the understanding of how integrated representations are retained in memory for the features of visual objects and the features of sounds, the research will provide new theoretical insights as well as new methods for investigating several forms of psychopathology. Deficits in feature binding have been argued to be implicated in autism, in the auditory hallucinations experienced by individuals with schizophrenia, and in memory decline with advancing age. By investigating these deficits using insights from the proposed study, researchers may be able to develop ways to ameliorate the adverse effects of the deficits.Read moreRead less
Face recognition: Properties and origins of whole-face processing. Humans identify other individuals almost entirely by their faces. Correspondingly, research has demonstrated a "special" style of cognitive processing that is unique to faces (at least in ordinary adults). The present project will address two major theoretical issues: (1) the exact nature of the special processing for faces, and (2) the extent to which it is innate, or learned. New progress in understanding these issues will be m ....Face recognition: Properties and origins of whole-face processing. Humans identify other individuals almost entirely by their faces. Correspondingly, research has demonstrated a "special" style of cognitive processing that is unique to faces (at least in ordinary adults). The present project will address two major theoretical issues: (1) the exact nature of the special processing for faces, and (2) the extent to which it is innate, or learned. New progress in understanding these issues will be made using a series of novel experimental techniques. These techniques isolate the specific contribution of the face recognition system, independent of contributions from object recognition, and from early visual processing.Read moreRead less