Investigating a new paradigm for plant-pathogen interactions; Identification of host-selective toxin proteins in the wheat pathogen Stagonospora nodorum. Stagonospora nodorum is a fungus that causes leaf and glume blotch disease on wheat. This disease alone causes $55 million dollars in yield losses per annum. Traditional breeding methods have yielded crops that are only mildly resistant leaving control of the disease to be worryingly reliant on fungicides. This project aims to identify and char ....Investigating a new paradigm for plant-pathogen interactions; Identification of host-selective toxin proteins in the wheat pathogen Stagonospora nodorum. Stagonospora nodorum is a fungus that causes leaf and glume blotch disease on wheat. This disease alone causes $55 million dollars in yield losses per annum. Traditional breeding methods have yielded crops that are only mildly resistant leaving control of the disease to be worryingly reliant on fungicides. This project aims to identify and characterise proteins that the fungus secretes to cause disease on wheat. By identifying these proteins, it is anticipated that strategies, both traditional and modern, could be employed to enable better control of the disease. This in turn would help provide a long term and secure supply of wheat and wheat based products to the community.Read moreRead less
Molecular characterisation of the fungal disease defence response in tropical sandalwood (Santalum album). The tropical sandalwood industry in Australia is a highly profitable and expanding enterprise; however this cannot be taken for granted. Fungal diseases in tropical plantations are of increasing concern to growers and left unchecked could result in substantial economic loss and an unsustainable industry. This research seeks to understand the defence response of the tree in order to develop ....Molecular characterisation of the fungal disease defence response in tropical sandalwood (Santalum album). The tropical sandalwood industry in Australia is a highly profitable and expanding enterprise; however this cannot be taken for granted. Fungal diseases in tropical plantations are of increasing concern to growers and left unchecked could result in substantial economic loss and an unsustainable industry. This research seeks to understand the defence response of the tree in order to develop tools to combat fungal disease by rapid selection of highly resistant trees. Essential oil production is also linked to the defence response. Understanding this response as well as exploring chemical means of increasing both disease resistance and oil production will deliver a substantial economic benefit to the expanding tropical sandalwood industry.Read moreRead less
Role of soil factors and transmission on propagation material of fungal pathogens in the severity of strawberry crown and root disorders. Through identification of the pathogen complexes associated with root and crown disorders, their impacts, understanding the influences of environmental conditions and rotational species, knowing the sources of major pathogens, and identification of varietal resistances to the pathogens, this project will provide a unique opportunity for growers to better manag ....Role of soil factors and transmission on propagation material of fungal pathogens in the severity of strawberry crown and root disorders. Through identification of the pathogen complexes associated with root and crown disorders, their impacts, understanding the influences of environmental conditions and rotational species, knowing the sources of major pathogens, and identification of varietal resistances to the pathogens, this project will provide a unique opportunity for growers to better manage such disorders of strawberries occurring across southern Australia. Benefits include prevention of severe losses in strawberries, making strawberry production and exports more viable, sustainable and environmentally friendly, addressing the National Research Priority 'An Environmentally Sustainable Australia' and the Priority Goal of 'Transforming existing industries".Read moreRead less
The biology, genetics, pathology and control of Alternaria species in Paulownia plantations. The development of Paulownia plantations is a rapidly expanding industry in Australia. Recently, three Alternaria species have been associated with foliar and canker disease leading to tree deaths. Alternaria disease has the potential to cause economic losses to the industry in Western Australia. Therefore, this study will examine the pathology and genetic diversity of Alternaria species, establish path ....The biology, genetics, pathology and control of Alternaria species in Paulownia plantations. The development of Paulownia plantations is a rapidly expanding industry in Australia. Recently, three Alternaria species have been associated with foliar and canker disease leading to tree deaths. Alternaria disease has the potential to cause economic losses to the industry in Western Australia. Therefore, this study will examine the pathology and genetic diversity of Alternaria species, establish pathogenicity screening of different genetic material and look at a range of integrated chemical and silvicultural approaches to reduce disease impact and severity.Read moreRead less
New Approaches to the Control of Post-Weaning Diarrhoea in Piglets. In Australia, post?weaning diarrhoea (PWD) in piglets is a major constraint to efficient and profitable production. Increasing levels of resistance to dietary antibiotics by gut pathogens such as Escherichia coli, the bacterium implicated in PWD, is a major reason for this problem. This research will identify nutritional means of controlling PWD and increasing production after weaning. This will be achieved by strategic nutritio ....New Approaches to the Control of Post-Weaning Diarrhoea in Piglets. In Australia, post?weaning diarrhoea (PWD) in piglets is a major constraint to efficient and profitable production. Increasing levels of resistance to dietary antibiotics by gut pathogens such as Escherichia coli, the bacterium implicated in PWD, is a major reason for this problem. This research will identify nutritional means of controlling PWD and increasing production after weaning. This will be achieved by strategic nutritional interventions in the pre-weaning and (or) post-weaning periods targeted at reducing bacterial pathogens in the gut. A reduction in PWD will increase the overall efficiency of pig production in Australia and reduce antibiotic use.Read moreRead less
DNA Method for Detection of Phytophthora cinnamomi in Soil and Plant Material. The need to impose strict quarantine procedures to prevent the spread of Jarrah Dieback disease hampers the activities of the mining, tourism, wildflower, nursery, and bee keeping industries. These procedures are time consuming and require a high degree of technical expertise. They result in false negatives facilitating the spread of the disease in asymptomatic material. This project will develop a DNA test for detec ....DNA Method for Detection of Phytophthora cinnamomi in Soil and Plant Material. The need to impose strict quarantine procedures to prevent the spread of Jarrah Dieback disease hampers the activities of the mining, tourism, wildflower, nursery, and bee keeping industries. These procedures are time consuming and require a high degree of technical expertise. They result in false negatives facilitating the spread of the disease in asymptomatic material. This project will develop a DNA test for detection of the pathogen in soil and plant material to make detection easier, quicker, and specific. The outcomes will be a test for detection of the dieback pathogen and technology to detect pathogens in soil samples.Read moreRead less
Practical application of gene silencing: is delivery of long double stranded ribonucleic acid (dsRNA) by plant cells efficient in conferring host resistance to parasitic nematodes? Nematode that attack plants cause $120 billion of crop losses worldwide. Chemicals used for their control are being phased out because of environmental concerns, and natural resistance is limited. The aim of this project is to use Australian IP to develop a new form of resistance to nematodes based on knowledge of th ....Practical application of gene silencing: is delivery of long double stranded ribonucleic acid (dsRNA) by plant cells efficient in conferring host resistance to parasitic nematodes? Nematode that attack plants cause $120 billion of crop losses worldwide. Chemicals used for their control are being phased out because of environmental concerns, and natural resistance is limited. The aim of this project is to use Australian IP to develop a new form of resistance to nematodes based on knowledge of the host-pathogen interactions. A successful outcome could contribute an additional 5-20% increase in crop yields (depending on the crop) through inherent resistance of crops to nematode pests. This would benefit rural communities and the national economy, and could also generate international royalties.Read moreRead less
Proteome mapping of the model fungal plant pathogen Stagonospora nodorum using LC-LC-MS/MS. Stagonospora nodorum is a fungus that causes leaf and glume blotch disease on wheat. This disease alone causes $55 million dollars in yield losses per annum in Australia. This project aims to identify the proteins produced by Stagonospora nodorum through the development of a new proteomics technique. Two clear benefits to the community resulting from this project will emerge. The first will be the expert ....Proteome mapping of the model fungal plant pathogen Stagonospora nodorum using LC-LC-MS/MS. Stagonospora nodorum is a fungus that causes leaf and glume blotch disease on wheat. This disease alone causes $55 million dollars in yield losses per annum in Australia. This project aims to identify the proteins produced by Stagonospora nodorum through the development of a new proteomics technique. Two clear benefits to the community resulting from this project will emerge. The first will be the expert training of a student in proteomics, a skill that is keenly sought. Secondly, the identification of these pathogen proteins will lead to new strategies to better control the disease and secure the supply of wheat.Read moreRead less
Molecular tools for controlling pathogenic viruses in the seed potato industry. In this project, molecular diagnostic tools will be generated that will improve the ability of testing laboratories to deliver cost-effective virus diagnostic services to seed potato certification authorities in Australia. There will be economic benefits from increased yields of fresh and processing potatoes, higher prices in domestic and export markets, expansion of current and development of new markets, and licen ....Molecular tools for controlling pathogenic viruses in the seed potato industry. In this project, molecular diagnostic tools will be generated that will improve the ability of testing laboratories to deliver cost-effective virus diagnostic services to seed potato certification authorities in Australia. There will be economic benefits from increased yields of fresh and processing potatoes, higher prices in domestic and export markets, expansion of current and development of new markets, and licensing of tests. There will also be economic and social returns to the broader rural community by better management and control of virus pathogens, and less reliance on environmentally undesirable chemical control measures. The project will provide expert training of two PhD students in practical and molecular plant virology. Read moreRead less
Missing Voices: Communication Difficulties After Stroke And Traumatic Brain Injury In Indigenous Australians
Funder
National Health and Medical Research Council
Funding Amount
$655,310.00
Summary
Acquired communication disorder (ACD) is a common result of stroke and traumatic brain injury (TBI) and has a devastating impact on victims’ everyday lives. Stroke and TBI occur more than twice as frequently in Indigenous as in non-Indigenous populations, but current uptake of communication rehabilitation services is low and long term outcomes for the individuals are unknown. This Australian first study will examine the extent and impact of ACD in urban and rural Indigenous Australians.