Reconstructing land tenure maps of Australia in 3D. Existing land tenure maps of above and below ground, such as apartment ownership, tunnels, and mining, are maintained using 2D drawings. However, the drawings are not structured and valuable for detailed and advanced visualisation, analytics, and simulation, which are essential for testing potential interventions and policy development. This project aims to develop a data validation framework for transforming current drawings and reconstructing ....Reconstructing land tenure maps of Australia in 3D. Existing land tenure maps of above and below ground, such as apartment ownership, tunnels, and mining, are maintained using 2D drawings. However, the drawings are not structured and valuable for detailed and advanced visualisation, analytics, and simulation, which are essential for testing potential interventions and policy development. This project aims to develop a data validation framework for transforming current drawings and reconstructing them into 3D models. The outcomes include validation principles, formal mathematical terms, and computational algorithms. Benefits include a cost-effective onshore alternative to offshore 3D reconstruction practices, efficient land development and infrastructure planning, and fewer property disputes.Read moreRead less
Sewer corrosion reduction through model-supported ventilation control. Ventilation is one of the key technologies for sewer corrosion control. However, its design and operation are currently based on experience and empirical equations, often leading to unsatisfactory results. By integrating in-depth laboratory and pilot-sewer studies under defined conditions with extensive field investigations, this multidisciplinary project aims to develop critical models to predict the corrosion process in res ....Sewer corrosion reduction through model-supported ventilation control. Ventilation is one of the key technologies for sewer corrosion control. However, its design and operation are currently based on experience and empirical equations, often leading to unsatisfactory results. By integrating in-depth laboratory and pilot-sewer studies under defined conditions with extensive field investigations, this multidisciplinary project aims to develop critical models to predict the corrosion process in response to ventilation and dynamic wastewater and atmospheric conditions, enabling model-based sewer ventilation design and operation. The project also aims to deliver novel, field-demonstrated ventilation strategies. The project findings will be incorporated in the Australian ventilation design and operation guidelines.Read moreRead less
Microstructural-Functional Effect of Silver Diammine Fluoride on Apatites. This project aims to develop a fundamental understanding at the nanostructural level of the factors that contribute to the enhanced mineralisation and mechanical properties of dentine and enamel following the treatment with silver diammine fluoride (SDF). A variety of advanced nanomechanical, tomographic and microscopic techniques will be used to characterise sound, carious and SDF treated tissue. The new biomechanical ev ....Microstructural-Functional Effect of Silver Diammine Fluoride on Apatites. This project aims to develop a fundamental understanding at the nanostructural level of the factors that contribute to the enhanced mineralisation and mechanical properties of dentine and enamel following the treatment with silver diammine fluoride (SDF). A variety of advanced nanomechanical, tomographic and microscopic techniques will be used to characterise sound, carious and SDF treated tissue. The new biomechanical evidence on the underlying mechanisms, alternative protocols, delivery systems enable to optimise the treatment. The scientific insights into arresting/repairing damage processes will provide critical data for developing minimal intervention protocols for pediatric and geriatric populations.Read moreRead less
Understanding molecular negative ion production for use in pathology. The project aims to increase the yield of molecular negative ion sources by improving our understanding of the formation of ion beams from plasma sources and expand our knowledge of molecular negative ion generation in plasma environments leading to brighter ion beams. For example, understanding cancer requires cellular level tools to map how cells are changing. These maps are made using ion beams which are scanned across cell ....Understanding molecular negative ion production for use in pathology. The project aims to increase the yield of molecular negative ion sources by improving our understanding of the formation of ion beams from plasma sources and expand our knowledge of molecular negative ion generation in plasma environments leading to brighter ion beams. For example, understanding cancer requires cellular level tools to map how cells are changing. These maps are made using ion beams which are scanned across cells to remove material that is analysed at the atomic and molecular level. Ion beams are produced from plasma sources, but much of their operation is not understood. Such improved ion beams are expected to enable inexpensive and fast cellular level pathology at even small hospitals to tackle cancer for society’s benefit.Read moreRead less
Engineering new tools to aid structure determination of membrane proteins. This project aims to address the inherent instability of G protein-coupled receptors (GPCRs), which are cell-surface proteins that are a major drug targets. The instability of GPCRs has resulted in a lack of atomic-level structural information that has hindered structure-based drug discovery efforts. This project expects to develop tools to improve GPCR stability and streamline the structure determination process. Project ....Engineering new tools to aid structure determination of membrane proteins. This project aims to address the inherent instability of G protein-coupled receptors (GPCRs), which are cell-surface proteins that are a major drug targets. The instability of GPCRs has resulted in a lack of atomic-level structural information that has hindered structure-based drug discovery efforts. This project expects to develop tools to improve GPCR stability and streamline the structure determination process. Project outcomes are intended to lead to significant advances in membrane protein structure determination and will have a substantial impact on future research in the pharmaceutical industry.Read moreRead less
Nanopore sensors for multiplexed, ultra-fast gene detection. The aim of this research is to develop the application of protein nanopores for multiplex identification of DNA samples for ultrafast gene detection. This is a type of barcoding of organism DNA that allows for rapid gene identification. This technology aims to address a significant need for rapid, on-the-spot identification of organisms. Applications include rapid identification of pathogenic bacteria in infections and identification o ....Nanopore sensors for multiplexed, ultra-fast gene detection. The aim of this research is to develop the application of protein nanopores for multiplex identification of DNA samples for ultrafast gene detection. This is a type of barcoding of organism DNA that allows for rapid gene identification. This technology aims to address a significant need for rapid, on-the-spot identification of organisms. Applications include rapid identification of pathogenic bacteria in infections and identification of organisms in environmental sampling. Current methods are relative slow, require DNA amplification and specialised laboratories.
This proposal aims to fine tune the properties of the large nanopore, polyC9, with respect to size and charge, as well as to identify and characterise novel large nanopores. Read moreRead less
Collision Avoidance in Shipping Lanes via Intelligent Sensor Data Fusion . This project aims to develop an online maritime traffic monitoring system for reliable collision/contact avoidance that exploits complementary data from high-resolution airborne sensors and surface vessel sensors. Our approach is based on optimal scheduling and fusion of the sensor data and possibly other sources of data to construct a comprehensive dynamic picture of maritime traffic, in real-time. Moreover, the proposed ....Collision Avoidance in Shipping Lanes via Intelligent Sensor Data Fusion . This project aims to develop an online maritime traffic monitoring system for reliable collision/contact avoidance that exploits complementary data from high-resolution airborne sensors and surface vessel sensors. Our approach is based on optimal scheduling and fusion of the sensor data and possibly other sources of data to construct a comprehensive dynamic picture of maritime traffic, in real-time. Moreover, the proposed methodology enables quantification of confidence in the predictions. This will provide ship owners, directly to their vessels and/or at the fleet management centres, information such as weather reports, reliable collision/no-collision warnings and avoidance strategies, on-the-fly. Read moreRead less
Metal folding fundamentals to shape new corrugated building products . FormFlow has developed a ground-breaking forming process enabling the use of corrugated iron as a structural element. This is a step change for Australia`s steel and building industry and will provide a direct benefit to fireproofing homes. Up scaling of this new technology poses significant challenges due to the lack of understanding in the new forming process and the effect of pre-processing on the incoming material. Fundam ....Metal folding fundamentals to shape new corrugated building products . FormFlow has developed a ground-breaking forming process enabling the use of corrugated iron as a structural element. This is a step change for Australia`s steel and building industry and will provide a direct benefit to fireproofing homes. Up scaling of this new technology poses significant challenges due to the lack of understanding in the new forming process and the effect of pre-processing on the incoming material. Fundamental knowledge of material behaviour will be developed with advanced models that account for the unique process deformation conditions. The intended outcome includes computer software for process design and new concepts for part shape control to improve product quality, repeatability and enable high volume manufacture.Read moreRead less
Flavour enhancing functional feeds for farmed Barramundi. This project aims to improve the flavour quality of Australian farmed barramundi through developing novel functional feeds. The project expects to expand our fundamental knowledge of flavour enhancement, whilst providing practical benefits with respect to final product quality. The project will enable industry to achieve higher product quality benchmarks, towards the ultimate goal of improving the marketability of barramundi both locally ....Flavour enhancing functional feeds for farmed Barramundi. This project aims to improve the flavour quality of Australian farmed barramundi through developing novel functional feeds. The project expects to expand our fundamental knowledge of flavour enhancement, whilst providing practical benefits with respect to final product quality. The project will enable industry to achieve higher product quality benchmarks, towards the ultimate goal of improving the marketability of barramundi both locally and overseas. This project will provide significant benefits to the Australian barramundi industry by increasing product values, thereby facilitating an economically sustainable growth of this important regional industry.Read moreRead less
Multiscale engineering of durable absorber coatings for solar thermal power. This project aims to advance the long-term stability and efficiency of high-temperature absorber coatings for Concentrated Solar Power (CSP) plants. Solar energy is a vast and largely untapped resource in Australia. The project will design superior light absorbers and scalable and low-cost approaches for their fabrication. Optimal absorber properties will be achieved by multi-scale engineering of the coating composition ....Multiscale engineering of durable absorber coatings for solar thermal power. This project aims to advance the long-term stability and efficiency of high-temperature absorber coatings for Concentrated Solar Power (CSP) plants. Solar energy is a vast and largely untapped resource in Australia. The project will design superior light absorbers and scalable and low-cost approaches for their fabrication. Optimal absorber properties will be achieved by multi-scale engineering of the coating composition and micro-texturing via modelling of the light absorption and heat transport within these complex nanocomposite structures. The intended outcome of the project is a set of commercially competitive absorber coatings, with superior performance and durability, that support the development of CSP as a competitive technology for energy generation.Read moreRead less