Nanoparticle radiosensitisation. This project aims to develop new knowledge through a better understanding of physics interactions of particles in compounds with sub-micron size. Research on radiosensitisation by sub-micrometre sized nanoparticles (NPs) is hot worldwide because it could treat cancer, but the physical/physico-chemical/biological mechanism of radiosensitisation is unclear because no physical models describe particle interactions at nanometre scale in solid state nanometre sized ob ....Nanoparticle radiosensitisation. This project aims to develop new knowledge through a better understanding of physics interactions of particles in compounds with sub-micron size. Research on radiosensitisation by sub-micrometre sized nanoparticles (NPs) is hot worldwide because it could treat cancer, but the physical/physico-chemical/biological mechanism of radiosensitisation is unclear because no physical models describe particle interactions at nanometre scale in solid state nanometre sized objects. This project will develop and evaluate specialised physics models to describe particle interactions in NPs and help optimise nanoparticle technology. It will develop expertise in Australia in physics modelling for nanomedicine and other applications of nanotechnology exposed to radiation (e.g. telecommunications, aviation and space).Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101101
Funder
Australian Research Council
Funding Amount
$348,741.00
Summary
Single-Molecule Circuitry for Nanoscale Electronic Devices. The aim of this project is to develop novel methods for forming robust single-molecule circuitry. The use of single molecules in electronics represents the next level of miniaturisation of electronic components, which would enable us to meet the expanding demands of modern technologies and to continue the downscaling trend in electronic devices. This project aims to address the requirements needed to translate single-molecule electronic ....Single-Molecule Circuitry for Nanoscale Electronic Devices. The aim of this project is to develop novel methods for forming robust single-molecule circuitry. The use of single molecules in electronics represents the next level of miniaturisation of electronic components, which would enable us to meet the expanding demands of modern technologies and to continue the downscaling trend in electronic devices. This project aims to address the requirements needed to translate single-molecule electronics from its current status as a fundamental tool to real-world applications. Key approaches will be the use of surface chemistry to develop new methods of wiring single molecules and the integration of robust single-molecule junctions with semiconducting electrodes. The expected project outcomes pave the way for single-molecule electronic and analytical devices.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120102906
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Topology optimisation for advanced engineered nanostructures. Advanced technological innovation requires extraordinary material properties, which can be generated directly from engineered nanostructures by manipulating surface plasmon resonances. The project will develop a new computational method for nanostructural design and expect to benefit aerospace, biomedical, optical and energy engineering fields.
Radiation detectors to better understand ion interactions. This project aims to build a Heavy Ion Therapy Research and Treatment Centre in Australia. Understanding how ions interact with matter and their radiobiological effectiveness (RBE) is important. The project will introduce an Australian detector technology platform to research ion interaction physics and their RBE. It will develop radiation detectors for ion measurement with a wide energy range, including a practical RBE quality assurance ....Radiation detectors to better understand ion interactions. This project aims to build a Heavy Ion Therapy Research and Treatment Centre in Australia. Understanding how ions interact with matter and their radiobiological effectiveness (RBE) is important. The project will introduce an Australian detector technology platform to research ion interaction physics and their RBE. It will develop radiation detectors for ion measurement with a wide energy range, including a practical RBE quality assurance tool with submillimetre spatial resolution. The proposed Australian radiation detection technology is expected to improve understanding of the scientific mechanisms underpinning the radiobiological effectiveness of heavy ion radiation.Read moreRead less
Unshackling solitons through ultimate dispersion control. The project aims to generate and investigate several novel families of self-stabilising optical pulses by using a unique fibre laser we recently devised. By developing the associated theoretical models, the team will transform conceptual and experimental knowledge of nonlinear physics, providing deep insights into fibre lasers and the pulses they can emit. The expected outcomes are a complete understanding of entirely novel families of op ....Unshackling solitons through ultimate dispersion control. The project aims to generate and investigate several novel families of self-stabilising optical pulses by using a unique fibre laser we recently devised. By developing the associated theoretical models, the team will transform conceptual and experimental knowledge of nonlinear physics, providing deep insights into fibre lasers and the pulses they can emit. The expected outcomes are a complete understanding of entirely novel families of optical pulses, and of the degree to which the energy required to generate these pulses can be reduced. Reducing this energy means that these pulses can perform the same function at lower power, which will enable the emergence of new applications that will play powerful roles in the 21st-century economy.Read moreRead less
Novel 2-photon atom manipulation for ultra-nanoscale processing of diamond. There is intense interest in exploiting diamond's remarkable properties in many fields of science and technology, but fabricating and processing devices remains a major challenge. This project will build on previous work, using a recently discovered novel laser-induced surface phenomenon that enables, for the first time for any material, the exciting prospect of using light to manipulate surface atoms with atomic precis ....Novel 2-photon atom manipulation for ultra-nanoscale processing of diamond. There is intense interest in exploiting diamond's remarkable properties in many fields of science and technology, but fabricating and processing devices remains a major challenge. This project will build on previous work, using a recently discovered novel laser-induced surface phenomenon that enables, for the first time for any material, the exciting prospect of using light to manipulate surface atoms with atomic precision. This project aims to elucidate the mechanisms underpinning the optical interaction to reveal its full potential and use it to address key problems in diamond nano-device fabrication that lie beyond the reach of current techniques. It is expected that the outcomes will directly enhance Australia's current strengths in diamond-based quantum and photonic technologies.Read moreRead less
A Dual-species Ion Trap with Precision Optical Clocks. This project will enable new technological capabilities to overcome challenges in scaling up quantum computation and advancing quantum clocks. It will develop a versatile dual-species atomic instrumentation paired with precision laser systems. This advanced technological platform will be augmented by an extensive toolbox of quantum control engineering protocols to perform error-robust quantum operations for fault-tolerant quantum computation ....A Dual-species Ion Trap with Precision Optical Clocks. This project will enable new technological capabilities to overcome challenges in scaling up quantum computation and advancing quantum clocks. It will develop a versatile dual-species atomic instrumentation paired with precision laser systems. This advanced technological platform will be augmented by an extensive toolbox of quantum control engineering protocols to perform error-robust quantum operations for fault-tolerant quantum computation and high-precision spectroscopy. The expected outcomes will also benefit other disciplines: advanced quantum simulations for chemical dynamics, precision spectroscopy for astronomy, next-generation lasers, tests of fundamental physics, and quantum-enhanced positioning, navigation, and timing. Read moreRead less
Enlightening single rare-earth atoms in scanning-tunnelling microscopy. This project aims to create a tool to systematically engineer optical properties of emitters in solids by understanding and manipulating materials atom by atom. The tool – an optically enhanced scanning tunnelling microscope – is expected to drive future developments in optical technologies. The project expects to deliver an atomic-scale understanding of rare-earth sites optimised for sensing and coherence. The expected outc ....Enlightening single rare-earth atoms in scanning-tunnelling microscopy. This project aims to create a tool to systematically engineer optical properties of emitters in solids by understanding and manipulating materials atom by atom. The tool – an optically enhanced scanning tunnelling microscope – is expected to drive future developments in optical technologies. The project expects to deliver an atomic-scale understanding of rare-earth sites optimised for sensing and coherence. The expected outcomes include highly developed theoretical insights into solid-state emitters and how to control their interactions with light and other fields. The expected benefit based on the ability to engineer optimised emitters for optical sensors and quantum technologies will transform material science from exploration to design.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100098
Funder
Australian Research Council
Funding Amount
$1,974,000.00
Summary
Enabling the Future of the Australian Collider Physics Program. The project aims to fund the continuation of Australia’s very successful experimental particle physics program to explore how the universe works at it's fundamental level. We interrogate subatomic matter at the energy frontier at CERN's Large Hadron Collider and the intensity frontier at Japan's SuperKEKB collider. The basic contributions required for Australian membership of these two key programs will enable scientists to continue ....Enabling the Future of the Australian Collider Physics Program. The project aims to fund the continuation of Australia’s very successful experimental particle physics program to explore how the universe works at it's fundamental level. We interrogate subatomic matter at the energy frontier at CERN's Large Hadron Collider and the intensity frontier at Japan's SuperKEKB collider. The basic contributions required for Australian membership of these two key programs will enable scientists to continue capitalising on decades of hard work and accumulated expertise, significant project outcomes and benefits include: access for Australia to advanced instruments and international research facilities; training of the next generation of researchers in detector construction and operation; and a rich science program.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100179
Funder
Australian Research Council
Funding Amount
$3,189,000.00
Summary
Automated high resolution and high contrast cryo -TEM for three-dimensional structural biology. This project aims to establish a facility in automated, single-particle cryo-TEM and cryo-TEM tomography (Titan Krios) that will enable atomic and molecular structure research and three-dimensional subcellular and cellular imaging. The project will span all multiscale cryo-TEM modalities from the visualisation of cells, membranes and macromolecular complexes, through to near-atomic-resolution protein ....Automated high resolution and high contrast cryo -TEM for three-dimensional structural biology. This project aims to establish a facility in automated, single-particle cryo-TEM and cryo-TEM tomography (Titan Krios) that will enable atomic and molecular structure research and three-dimensional subcellular and cellular imaging. The project will span all multiscale cryo-TEM modalities from the visualisation of cells, membranes and macromolecular complexes, through to near-atomic-resolution protein structure determination. Cryo-single particle analysis and tomography are recognised as revolutionary technologies in molecular structural biology and powerful enablers of future ground-breaking discovery. The project will deliver significant competitive advantage for Australia in leading-edge structure-based research, drug discovery, new opportunities for applied research and development, and showcasing science to the public.Read moreRead less