Organisation, expression and diversity of the sub-telomeric regions of the ancient eukaryote, Giardia duodenalis. We propose to extend our findings on the extreme plasticity of the structure and organisation of the sub-telomeric region of the complete genome of Giardia by more extensive chromosome walking, and comparison of different isolates. These regions are subject to gene conversion, transcriptional silencing, gene mobility, recombination, variable surface protein expression, subtelomeric i ....Organisation, expression and diversity of the sub-telomeric regions of the ancient eukaryote, Giardia duodenalis. We propose to extend our findings on the extreme plasticity of the structure and organisation of the sub-telomeric region of the complete genome of Giardia by more extensive chromosome walking, and comparison of different isolates. These regions are subject to gene conversion, transcriptional silencing, gene mobility, recombination, variable surface protein expression, subtelomeric instability and the insertion of transposable elements, a dynamic balance between structural conservation and rapid evolution. This is a rare opportunity to understand the forces at work in moulding eukaryotic sub-telomeric sequences because Giardia is not constrained by sexual homogenisation and the dynamic variability is retained.Read moreRead less
ARC Centre of Excellence - Centre for Antimatter-Matter Studies. While our world is made of matter, all particles have anti-particles and the most abundant is the positron, the electron's antiparticle. It is the "workshop" for most anti-matter studies, particularly for the characterization of materials, including gases, polymers, insulators, thin films and surfaces, as well as the development of new and novel, nano-structured materials. The ARC Centre of Excellence in Antimatter-Matter Studies ....ARC Centre of Excellence - Centre for Antimatter-Matter Studies. While our world is made of matter, all particles have anti-particles and the most abundant is the positron, the electron's antiparticle. It is the "workshop" for most anti-matter studies, particularly for the characterization of materials, including gases, polymers, insulators, thin films and surfaces, as well as the development of new and novel, nano-structured materials. The ARC Centre of Excellence in Antimatter-Matter Studies (CAMS) will bring together key Australian and international scientists to work in this emerging scientific field of antimatter-matter interactions. It will forge a unique and effective scientific team for state-of-the-art studies of the nano-world that underlies many everyday processes and new technologies.Read moreRead less
Power scaling of remote plasma sources for gallium nitride film growth with real-time monitoring of activated nitrogen species. Domestic, industrial and community lighting currently accounts for ~20% of the world's overall energy consumption. Commonly used incandescent lights are based on inefficient, century-old technologies. In contrast, light emitting diodes (LEDs) use ~80% less energy and last ~100 times longer. LED deployment will bring substantial economic and environmental benefits for Au ....Power scaling of remote plasma sources for gallium nitride film growth with real-time monitoring of activated nitrogen species. Domestic, industrial and community lighting currently accounts for ~20% of the world's overall energy consumption. Commonly used incandescent lights are based on inefficient, century-old technologies. In contrast, light emitting diodes (LEDs) use ~80% less energy and last ~100 times longer. LED deployment will bring substantial economic and environmental benefits for Australia and globally. Next generation high-efficiency LEDs for lighting, will operate with reduced energy consumption, thus contributing to reaching future national targets for CO2 emission reduction. This project will achieve reduced production cost of a key LED material, and will support Australia's leadership in a growing global semiconductor manufacturing industry.Read moreRead less
Kingdom switching microbial pathogens: the bioinformatics of mutation in the genomes of viruses and bacteria affecting crops, livestock and people. Some organisms that cause infectious diseases have moved between plants and vertebrates, either recently or repeatedly over evolutionary time. Switching between plants and vertebrates strongly influences the way these microbes mutate and evolve. We will search the genomic sequence databases for information about how the choice of host influences muta ....Kingdom switching microbial pathogens: the bioinformatics of mutation in the genomes of viruses and bacteria affecting crops, livestock and people. Some organisms that cause infectious diseases have moved between plants and vertebrates, either recently or repeatedly over evolutionary time. Switching between plants and vertebrates strongly influences the way these microbes mutate and evolve. We will search the genomic sequence databases for information about how the choice of host influences mutations in viral and bacterial genomes and model the evolutionary processes involved. This project will advance our understanding of the fine structure of microbial genomes and the importance of selection pressures on genes. It will lead to better disease management strategies for humans, and for domestic crops and livestock.Read moreRead less
Physics of High Power Pulsed Plasmas for Materials Synthesis. The new science produced will have a direct benefit on the synthesis of a new generation of materials for many applications, such as transparent conductive oxides, multilayer structures, and heat mirror materials for glazings. Many of these materials will help reduce energy consumption in the built environment and hence Australia's emission of greenhouse gases. Furthermore, it will help to develop environmentally clean production met ....Physics of High Power Pulsed Plasmas for Materials Synthesis. The new science produced will have a direct benefit on the synthesis of a new generation of materials for many applications, such as transparent conductive oxides, multilayer structures, and heat mirror materials for glazings. Many of these materials will help reduce energy consumption in the built environment and hence Australia's emission of greenhouse gases. Furthermore, it will help to develop environmentally clean production methods for many existing as well as new applications by replacing liquid based production techniques such as electroplating which generate toxic liquid wastes. Read moreRead less
Visualizing spin-related properties of functional nanostructures (for spintronics). This project contributes to undergraduate, postgraduate and postdoctoral research and training to encourage the pursuit of excellence, with:
- increased depth of knowledge in interdisciplinary research,
- a scientific environment providing access to research not otherwise in Australia,
- experience in the design, construction and development of scientific instruments.
Possible applications include high-speed ....Visualizing spin-related properties of functional nanostructures (for spintronics). This project contributes to undergraduate, postgraduate and postdoctoral research and training to encourage the pursuit of excellence, with:
- increased depth of knowledge in interdisciplinary research,
- a scientific environment providing access to research not otherwise in Australia,
- experience in the design, construction and development of scientific instruments.
Possible applications include high-speed magnetic filters, sensors, quantum transistors and spin qubits for quantum computers. The technological aspects of our project's outcomes offer real prospects of local development. The development of spin-polarized electron spectroscopy has great potential for existing applications in the surface science industry.
Read moreRead less
A Cost-Effective System for Monitoring Lightning Strikes Across Australasia. Lightning causes many major fires in Australia, and rural fire managers would benefit from access to lighting data. Lightning data have been prohibitively expensive because acquiring them requires a dense monitoring network. Low Frequency Electromagnetic Research Ltd (LF*EM) has developed an alternative, cost-effective technology for monitoring lightning based on a sparse network of stations monitoring VLF radiation. We ....A Cost-Effective System for Monitoring Lightning Strikes Across Australasia. Lightning causes many major fires in Australia, and rural fire managers would benefit from access to lighting data. Lightning data have been prohibitively expensive because acquiring them requires a dense monitoring network. Low Frequency Electromagnetic Research Ltd (LF*EM) has developed an alternative, cost-effective technology for monitoring lightning based on a sparse network of stations monitoring VLF radiation. We propose to translate LF*EM's basic science results into a product that can deliver lightning data to fire managers and other users across Oceania.Read moreRead less
Structure of Exotic Neutron-Rich Nuclei Populated Using Novel Reaction Mechanisms. Over half of the nuclei believed to be stable to particle decay have not been studied due to the lack of available nuclear reactions. We have played a leading role in developing innovative techniques using incomplete-fusion and deep-inelastic reactions to access neutron-rich nuclei that were inaccessible prior to this work. This project aims to study new phenomena in exotic, neutron-rich nuclei, building on Aust ....Structure of Exotic Neutron-Rich Nuclei Populated Using Novel Reaction Mechanisms. Over half of the nuclei believed to be stable to particle decay have not been studied due to the lack of available nuclear reactions. We have played a leading role in developing innovative techniques using incomplete-fusion and deep-inelastic reactions to access neutron-rich nuclei that were inaccessible prior to this work. This project aims to study new phenomena in exotic, neutron-rich nuclei, building on Australia's existing investment in this area, and, through international scientific leadership, facilitating the access of Australian researchers to highly competitive overseas facilities.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL0992247
Funder
Australian Research Council
Funding Amount
$2,988,295.00
Summary
Advances at the frontiers of subatomic physics and cross-disciplinary applications of the associated techniques. The candidate is an international scientific leader, in terms of his own research, his responsibilities within the United States Department of Energy (DoE) and his role as Chair of the International Union of Pure and Applied Physics (IUPAP) Working Group on International Cooperation in Nuclear Physics. His return to South Australia to establish a major new research centre in the physi ....Advances at the frontiers of subatomic physics and cross-disciplinary applications of the associated techniques. The candidate is an international scientific leader, in terms of his own research, his responsibilities within the United States Department of Energy (DoE) and his role as Chair of the International Union of Pure and Applied Physics (IUPAP) Working Group on International Cooperation in Nuclear Physics. His return to South Australia to establish a major new research centre in the physical sciences will dramatically enhance the State's reputation in science and engineering, an essential component of its contribution to the nation's defence. It will underline Australia's commitment to contribute its share to advancing fundamental science. The involvement of senior researchers from fields as diverse as applied optics and mathematical biology will ensure that the opportunities for cross-disciplinary research are fully exploited.Read moreRead less
Development of Nuclear Quadrupole Resonance Methods and Technology to Enhance the Detection of Explosives and Other Contraband. This project will develop new methods and technology for the detection of explosives and other compounds using Nuclear Quadrupole Resonance. This technique is of great importance to aviation security and the military and is particularly relevant to the priority goal of 'Safeguarding Australia'. The Industry partner has licensing contracts with major x-ray manufacturer ....Development of Nuclear Quadrupole Resonance Methods and Technology to Enhance the Detection of Explosives and Other Contraband. This project will develop new methods and technology for the detection of explosives and other compounds using Nuclear Quadrupole Resonance. This technique is of great importance to aviation security and the military and is particularly relevant to the priority goal of 'Safeguarding Australia'. The Industry partner has licensing contracts with major x-ray manufacturers and system integrators to integrate this technology. These investigations should yield improvements in the signal to noise ratio, false alarm rates and the spatial discrimination of targets. This work will lead to significant increases in the value of the technology and open up new areas of commercialization.Read moreRead less