Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882531
Funder
Australian Research Council
Funding Amount
$250,000.00
Summary
Quantum Limited Single Atom Detectors. The technology that has shaped our society, solid state diodes, transistors and computer chips is based on our ability to manipulate the average quantum properties of materials such as semiconductors. This physics has been well understood for decades. Many technologies that will shape our societies in this century will be based on our ability to manipulate quantum systems precisely, an area that is the focus of quantum atom optics. The detectors requested i ....Quantum Limited Single Atom Detectors. The technology that has shaped our society, solid state diodes, transistors and computer chips is based on our ability to manipulate the average quantum properties of materials such as semiconductors. This physics has been well understood for decades. Many technologies that will shape our societies in this century will be based on our ability to manipulate quantum systems precisely, an area that is the focus of quantum atom optics. The detectors requested in this proposal will ensure that Australia remains competitive in the technologies that will emerge from the new field of quantum atom optics.Read moreRead less
Australian Centre for Quantum-Atom Optics. The Centre will combine pre-eminent Australian theoretical and experimental research groups in quantum and atom optics to create a powerful network to advance the rapidly developing field of Quantum-Atom Optics. We will exploit the quantum nature of multiple particle quantum states of atoms and photons including entangled light and Bose-Einstein condensates. The Centre will focus on fundamental research, but our long term goal is to underpin and develo ....Australian Centre for Quantum-Atom Optics. The Centre will combine pre-eminent Australian theoretical and experimental research groups in quantum and atom optics to create a powerful network to advance the rapidly developing field of Quantum-Atom Optics. We will exploit the quantum nature of multiple particle quantum states of atoms and photons including entangled light and Bose-Einstein condensates. The Centre will focus on fundamental research, but our long term goal is to underpin and develop the next generation quantum technology. We aim to build a quantum toolbox to enable applications such as the transfer and storage of information for photonics, and precision quantum control of atoms for enhanced atom interferometry.Read moreRead less
Discovering And Targeting Genes Regulating Skeletal Muscle Function, Metabolism, And Adaptations To Exercise Interventions
Funder
National Health and Medical Research Council
Funding Amount
$431,000.00
Summary
Muscle wasting and decreased in mitochondrial function due to ageing or lack of physical activity are associated with reduced quality of life. The overarching aim is to develop a unique research program focusing on targeting specific genes, and to discover novel genes regulating muscle wasting and mitochondrial (dis)function. I anticipate this approach to assist in the development of targeted and personalised prevention and therapy for diseases associated with muscle (dis)function.
Molecular Characterisation Of Early Precursor Lesions Of A Novel Ñserrated Pathwayî Of Colorectal Cancer Using Gene Expression And Proteomics.
Funder
National Health and Medical Research Council
Funding Amount
$318,338.00
Summary
In Australia, CRC is the second highest cause of all cancer-related deaths. If detected early, CRC has a high success rate of cure, but a percentage of precursor lesions escape detection and show aggressive clinical behaviour to progress to CRC. These are difficult to diagnosis with existing technologies. We aim to understand the biology behind sessile serrated adenoma pathways and hence enhance early detection, diagnosis and treatments strategies.
Atomic scale imaging with high coherence electrons and ions. This project aims to combine a cold atom electron-ion source with a commercial microscope column for atomic-scale imaging in biosciences and materials science. Nanoscale imaging with electron and ion microscopy are tools for investigating the world at the atomic scale, underpinning development in modern technologies from semiconductor devices to medical treatments. This project will use ideas from laser cooling of atoms and atom optics ....Atomic scale imaging with high coherence electrons and ions. This project aims to combine a cold atom electron-ion source with a commercial microscope column for atomic-scale imaging in biosciences and materials science. Nanoscale imaging with electron and ion microscopy are tools for investigating the world at the atomic scale, underpinning development in modern technologies from semiconductor devices to medical treatments. This project will use ideas from laser cooling of atoms and atom optics to achieve new imaging modalities for time-lapse imaging of fundamental processes at the nano-scale. It will allow increasingly small scale resolution of fundamental processes at the nano-scale.Read moreRead less
Calibrating Cosmology: The Near-Field Approach to Galaxy Formation. Understanding the formation and evolution of structure in the early Universe continues to elude astronomers. Studying these earliest epochs is the driver for billion-dollar investments like the Next Generation Space Telescope and the Square Kilometre Array (with Australia as a primary partner). Our complementary 'near-field cosmology' project is unique, blending strengths in computational cosmology, stellar nucleosynthesis, and ....Calibrating Cosmology: The Near-Field Approach to Galaxy Formation. Understanding the formation and evolution of structure in the early Universe continues to elude astronomers. Studying these earliest epochs is the driver for billion-dollar investments like the Next Generation Space Telescope and the Square Kilometre Array (with Australia as a primary partner). Our complementary 'near-field cosmology' project is unique, blending strengths in computational cosmology, stellar nucleosynthesis, and optical astronomy, to 'deconstruct' the formation history of the one galaxy with detailed chemical and kinematical information - our own Milky Way. Combining theory and observation, cosmology and nucleosynthesis, we will produce the template for galaxy formation, providing the anchor for 'far-field' cosmology.Read moreRead less
ARC Centre of Excellence in Plants for Space. ARC Centre of Excellence in Plants for Space. This Centre aims to create on-demand, zero-waste, high-efficiency plants and plant products to address grand challenges in sustainability for Space and on Earth. Significant advances in plant, food, and sensory science; process and systems engineering; law and policy; and psychology are expected to deliver transformative solutions for Space habitation – and create enhanced plant-derived food and bioresour ....ARC Centre of Excellence in Plants for Space. ARC Centre of Excellence in Plants for Space. This Centre aims to create on-demand, zero-waste, high-efficiency plants and plant products to address grand challenges in sustainability for Space and on Earth. Significant advances in plant, food, and sensory science; process and systems engineering; law and policy; and psychology are expected to deliver transformative solutions for Space habitation – and create enhanced plant-derived food and bioresources to capitalise upon emergent and rapidly expanding domestic and global markets. Anticipated outcomes include industry uptake of innovative plant forms, foods, technologies, and commodities; and an ambitious education and international co-ordination agenda to position Australia as a global leader in research supporting Space habitation.Read moreRead less
Auger, Quantum Electro-Dynamics, Axions and New Technology. New technology developed by Australia, Sweden and the United States will be applied to major questions about the application of relativistic quantum mechanics to atomic structure and dynamics and spectroscopy, especially including critical issues in quantum electro-dynamics for atomic physics and applications. Discrepancies in quantum electro-dynamics have dominated international debate for decades, with claimed explanations annually fa ....Auger, Quantum Electro-Dynamics, Axions and New Technology. New technology developed by Australia, Sweden and the United States will be applied to major questions about the application of relativistic quantum mechanics to atomic structure and dynamics and spectroscopy, especially including critical issues in quantum electro-dynamics for atomic physics and applications. Discrepancies in quantum electro-dynamics have dominated international debate for decades, with claimed explanations annually failing to reveal the cause. Also a pattern of discrepancies has been seen at X-ray energies in first row metal atoms, with a similar sign and magnitude. A combined experimental an theoretical investigation will aim to reveal new light on these anomalies and serve to develop our understanding of the universe.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882493
Funder
Australian Research Council
Funding Amount
$700,000.00
Summary
High-accuracy spectroscopy under extreme conditions: combining novel synchrotron and laboratory-based spectroscopy. This project aims at maintaining the leading position of Australia in nationally important fields such as ore and environmental geology, ore processing and metallurgy, nano- and bio-technology. This project aims to establish an integrated set of state-of-the-art, often unique and revolutionary new tools, taking in particular advantage of local innovation in instrumentation and spec ....High-accuracy spectroscopy under extreme conditions: combining novel synchrotron and laboratory-based spectroscopy. This project aims at maintaining the leading position of Australia in nationally important fields such as ore and environmental geology, ore processing and metallurgy, nano- and bio-technology. This project aims to establish an integrated set of state-of-the-art, often unique and revolutionary new tools, taking in particular advantage of local innovation in instrumentation and spectroscopy theory, of the investment in major facilities (Australian Synchrotron). By improving cross-disciplinary links among research groups interested in in-situ spectroscopy (Earth Sciences, Physics, Chemistry, Biological Sciences, Biochemistry, Biomedicine, Engineering), this application will results in major scientific and industrial advances.Read moreRead less
Adaptive Evolution of BRCA1 in Ancestral Mammals. This project investigates adaptive evolution of BRCA1 in the early radiation of mammals. We will test the hypothesis that the evolution of mammary glands and X chromosome inactivation has resulted in modification of the BRCA1 protein sequence as it aquired new roles in these processes. We will also investigate the importance of these changes inducing compensatory changes in other parts of the protein.