Centre Of Research Excellence - REduce The Burden Of Antimicrobial ReSistance Through OPtimal, PersONalised Dosing (RESPOND)
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
Each year more than 17 million people die from infectious diseases. Many of these deaths are due to the poor use of antimicrobial drugs and an increase in infections caused by antimicrobial-resistant 'superbugs'. CRE RESPOND will enable an optimal treatment of infection by empowering clinicians with an evidence-based, patient-centred approach to guide antimicrobial dosing. We will generate new knowledge, educate healthcare workers, and build research capacity through our network of collaborators
National Centre For Research Excellence In Neuromuscular Disorders: Transforming The Management Of Neuromuscular Disorders From Compassionate Assistance To Targeted Therapy And Prevention
Funder
National Health and Medical Research Council
Funding Amount
$2,805,509.00
Summary
Neuromuscular disorders affect 1 in 1,000 people, often result in progressive muscle weakness and can cause early death. At present not enough is being done to ensure translation of research into improved outcomes for patients. For the first time in Australia, the CRE-NMD will establish an integrated, comprehensive program to investigate diagnosis, prevention and treatment of neuromuscular disorders from infancy to adulthood.
Protecting The Public From Emerging Infectious Diseases
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
Emerging infectious diseases and pandemics cause potentially enormous but unpredictable health and socioeconomic impacts. This CRE will develop and integrate new technologies, including fingerprinting the entire gene complement of micro-organisms and new electronic communication platforms, to improve the precision and speed of public health responses. We will develop ethics research-based policy frameworks to enable implementation of these technologies into public health practice and policy.
Centre For REdefining Antibiotic Use To ReDUce ResistanCE And Prolong The Lives Of Antibiotics (REDUCE)
Funder
National Health and Medical Research Council
Funding Amount
$2,158,296.00
Summary
Ineffective dosing of antimicrobials has contributed to the escalation of antimicrobial resistance which now pervades the healthcare system. Patients in the intensive care unit and post-transplant are examples of patients who commonly have infections, are more likely to fail treatment and have resistant microbes emerge. In these studies we will characterise the doses of antimicrobials that should be used in these difficult-to-treat patients and rapidly share these for routine clinical use.