Improving young people's online safety when talking about suicide. This project aims to improve the safety and quality of online communication about suicide by young people. Suicide is the leading cause of death among young Australians and rates continue to rise. One commonly cited explanation for this is the way in which young people use social media to communicate about suicide. This project will directly address this by testing the impact of a set of evidence-informed guidelines and campaign ....Improving young people's online safety when talking about suicide. This project aims to improve the safety and quality of online communication about suicide by young people. Suicide is the leading cause of death among young Australians and rates continue to rise. One commonly cited explanation for this is the way in which young people use social media to communicate about suicide. This project will directly address this by testing the impact of a set of evidence-informed guidelines and campaign materials that target young people’s capacity to communicate about suicide safely on social media. Expected outcomes of this project include increased online safety for young people. This study also has national and international significance for the social media industry and the safe governance of their platforms. Read moreRead less
Understanding the long term impact of childhood emotional abuse. This project will generate new knowledge about the social dimensions of childhood emotional abuse. Experiences of childhood emotional abuse are extremely common, with many affected individuals going on to face long term health problems, social marginalisation, intergenerational family violence and re-victimisation. This project will investigate how different social contexts influence childhood emotional abuse itself and the interco ....Understanding the long term impact of childhood emotional abuse. This project will generate new knowledge about the social dimensions of childhood emotional abuse. Experiences of childhood emotional abuse are extremely common, with many affected individuals going on to face long term health problems, social marginalisation, intergenerational family violence and re-victimisation. This project will investigate how different social contexts influence childhood emotional abuse itself and the interconnected problems flowing from it that often persist over the life course. The findings of this project will increase the evidence base and inform the future development of policy and practice that aims to prevent the intergenerational transmission of violence and abuse, and improve health and social outcomes. Read moreRead less
Determining the physical and temporal properties of a person's inner speech. Inner speech refers to the silent production of words in one's mind. While inner speech has long been assumed to be unquantifiable, we have recently demonstrated an ability to decipher the content a person's inner speech using an objective electrophysiological marker. In this project, we will extend upon this work and use our marker to establish the physical and temporal properties of a person's inner speech, such as it ....Determining the physical and temporal properties of a person's inner speech. Inner speech refers to the silent production of words in one's mind. While inner speech has long been assumed to be unquantifiable, we have recently demonstrated an ability to decipher the content a person's inner speech using an objective electrophysiological marker. In this project, we will extend upon this work and use our marker to establish the physical and temporal properties of a person's inner speech, such as its loudness, pitch, accent and temporal properties. Our hope is that our modified marker will be capable of determining what a person is saying in inner speech, when they are engaged in inner speech, and also how their inner voice sounds. This work has major implications with regards to technology, health, and basic science. Read moreRead less
Taking control: variations in forced psychiatric treatment in the community. This interdisciplinary project aims to produce a comprehensive understanding of the drivers underpinning variations in the use of legal orders to enforce psychiatric treatment in the community without consent. Australia’s rate of use of these controversial orders is very high and there are unexplained variations in rates of use within and between jurisdictions, with some minority groups disproportionately affected. Unco ....Taking control: variations in forced psychiatric treatment in the community. This interdisciplinary project aims to produce a comprehensive understanding of the drivers underpinning variations in the use of legal orders to enforce psychiatric treatment in the community without consent. Australia’s rate of use of these controversial orders is very high and there are unexplained variations in rates of use within and between jurisdictions, with some minority groups disproportionately affected. Uncovering this knowledge will act as a form of procedural justice for those who have had their human rights limited by compulsion. This knowledge is expected to lead to innovations in law and policy, with subsequent organisational and system improvements, generating profound benefits for those affected by forced treatment. Read moreRead less
Tranquillising Work Stress: Corporate Climate and Antidepressant Use. This national project will investigate the plausible link between distress at work and Australia’s high levels of antidepressant use, through creative linkage of data from the Australian Workplace Barometer (10-year longitudinal study) to antidepressant medication data (via the national Pharmaceutical Benefits Scheme). The project advances theory by probing the role corporate climate plays in work design, distress, mental hea .... Tranquillising Work Stress: Corporate Climate and Antidepressant Use. This national project will investigate the plausible link between distress at work and Australia’s high levels of antidepressant use, through creative linkage of data from the Australian Workplace Barometer (10-year longitudinal study) to antidepressant medication data (via the national Pharmaceutical Benefits Scheme). The project advances theory by probing the role corporate climate plays in work design, distress, mental health problems and antidepressant use. It will determine if antidepressant use has led to an underestimation of work stress effects. It will estimate the $AUD cost of work related antidepressant use. The project will yield evidence to stimulate corporate climate change to protect worker psychological health and wellbeing.Read moreRead less
Hippocampal regulation of goal-directed decision-making. The hippocampus is a part of the brain that is central to learning and memory yet little is known about its role in decision-making. It is the aim of this application to provide the first detailed, causal evidence of hippocampal regulation of decision-making. This is significant because many mental health disorders and dementias that involve decision-making deficits are characterised by hippocampal dysfunction, but any direct link between ....Hippocampal regulation of goal-directed decision-making. The hippocampus is a part of the brain that is central to learning and memory yet little is known about its role in decision-making. It is the aim of this application to provide the first detailed, causal evidence of hippocampal regulation of decision-making. This is significant because many mental health disorders and dementias that involve decision-making deficits are characterised by hippocampal dysfunction, but any direct link between these factors is unknown. The outcomes of the current grant will provide the first evidence of that link, thus providing deeper understanding of the neurophysiological mechanisms of these disorders, which could eventuate in the creation of more beneficial treatments. Read moreRead less
Novel dopamine pathways underlying motivated behaviours. Rewards such as food, sex and social media are seeked on daily basis. Neurological and psychological basis of learning and memory of reward processing behaviour. This project maps real time neural activity during reward processing in two novel brain regions. It has the potential to revolutionize the understanding of the brain mechanisms in reward processing. The biological data obtained can be directly integrated into computational modelli ....Novel dopamine pathways underlying motivated behaviours. Rewards such as food, sex and social media are seeked on daily basis. Neurological and psychological basis of learning and memory of reward processing behaviour. This project maps real time neural activity during reward processing in two novel brain regions. It has the potential to revolutionize the understanding of the brain mechanisms in reward processing. The biological data obtained can be directly integrated into computational modelling approaches to benefit reward processing algorithms for learning behaviours in humans or artificial intelligence. This project will fuel the understanding of algorithms driving social media platforms and consumer consumption, hence driving economic and technological progress in Australia.Read moreRead less
Investigating the role of Zona Incerta RXFP3+ cells in learning and memory. Learning and memory are fundamental to human and animal behaviour. We identified a specific population of cells in the zona incerta of the brain, where activation inhibits expression of memory, and facilitates the acquisition of new learning. Aside from our observations, nothing is currently known about the anatomy and function of these cells. This project aims to map how they connect to the rest of the brain, to observe ....Investigating the role of Zona Incerta RXFP3+ cells in learning and memory. Learning and memory are fundamental to human and animal behaviour. We identified a specific population of cells in the zona incerta of the brain, where activation inhibits expression of memory, and facilitates the acquisition of new learning. Aside from our observations, nothing is currently known about the anatomy and function of these cells. This project aims to map how they connect to the rest of the brain, to observe how these connections are recruited during learning and memory, and then to test their function experimentally. The outcomes will extend the known neural circuitry that controls learning by defining how and where these unexplored pathways fit within it; thus advancing knowledge regarding neural regulation of behaviour.
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Hunger flexibly modifies hypothalamic neural circuits responding to threat. Animal and human behaviour frequently involves a choice between actions or goals with conflicting positive and negative outcomes. However, the appropriate action or goal in conflicting situations often depends on physiological pressures like hunger, stress and mating opportunities. For example, the need for resources within an environment, such as food, drives approach behaviour, whereas threats to survival, such as pred ....Hunger flexibly modifies hypothalamic neural circuits responding to threat. Animal and human behaviour frequently involves a choice between actions or goals with conflicting positive and negative outcomes. However, the appropriate action or goal in conflicting situations often depends on physiological pressures like hunger, stress and mating opportunities. For example, the need for resources within an environment, such as food, drives approach behaviour, whereas threats to survival, such as predator cues, enhance avoidance behaviour. This project will uncover the neural circuitry and endocrine mechanisms through which hunger influences hypothalamic threat-detecting circuits that suppress food intake. These studies provide a new hypothalamic model to understand risk/reward decision in the brain.Read moreRead less