Improving The Mental Health Outcomes Of People With Intellectual Disability
Funder
National Health and Medical Research Council
Funding Amount
$1,189,979.00
Summary
Australians with intellectual disability (ID) have very high rates of mental illness but experience very poor access to mental health services. Our research will develop a sound evidence base on the profile of mental ill health, service use, pathways to care and mental health policy for people with intellectual disability. Together with consumers and support persons we will examine ways to improve mental health services for people with intellectual disability.
Selective Estrogen Receptor Modulators (SERMs) - A Potential New Treatment For Women Of Child-bearing Age With Psychotic Symptoms Of Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$210,480.00
Summary
Schizophrenia is a devastating illness urgently requiring a new treatment approach. We have discovered that estrogen is an effective treatment for women with schizophrenia and are currently trialling a safer Selective Estrogen Receptor Modulator (SERM) known as brain estrogen� in postmenopausal women with schizophrenia. Regulatory permission is now available to trial the SERM in younger women, and we seek to extend our current SERM study into child bearing age women with schizophrenia.
Improving The Cardiometabolic Health Of People With Psychosis: The Physical Health Nurse Consultant Service
Funder
National Health and Medical Research Council
Funding Amount
$667,021.00
Summary
People with psychosis have high rates of chronic disease that reduces lifespan by 25 years. The health system struggles to provide adequate care. We developed the Physical Health Nurse Consultant service that provides physical health care coordination and will evaluate whether it improves physical health, consumer experience and cost-effectiveness. Outcomes will directly address policy initiatives to improve physical health service delivery in mental health services.
From Brain Maps To Mechanisms: Modeling The Pathophysiology Of Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$320,891.00
Summary
My Fellowship will develop a framework that integrates brain imaging data with mathematical models of the brain to help understand the mechanisms responsible for schizophrenia. By linking functional Magnetic Resonance Imaging (fMRI) measurements to models of their underlying causes, the work may lead to new treatments that target the specific dysfunction in individuals with this debilitating brain disorder.
A Randomised Control Trial Of Non-specific Clinical Management Versus CBT In Chronic Anorexia Nervosa
Funder
National Health and Medical Research Council
Funding Amount
$555,843.00
Summary
Anorexia nervosa (AN) is a serious mental illness that usually starts in adolescence and often runs a chronic course. With an estimated prevalence rate between 0.5% and 3.7% of women, and up to 50% remaining chronically ill, the illness poses a disproportionate burden on health and social services. AN has inpatient costs alone that exceed that for schizophrenia. Chronic AN has the highest mortality rate of any mental illness. Chronic AN patients are known for their ambivalence about engaging in ....Anorexia nervosa (AN) is a serious mental illness that usually starts in adolescence and often runs a chronic course. With an estimated prevalence rate between 0.5% and 3.7% of women, and up to 50% remaining chronically ill, the illness poses a disproportionate burden on health and social services. AN has inpatient costs alone that exceed that for schizophrenia. Chronic AN has the highest mortality rate of any mental illness. Chronic AN patients are known for their ambivalence about engaging in treatment and poor motivation to change their eating disorder behaviours. They often fail to respond to traditional treatments and develop a history of negative treatment experiences and repeated treatment failures. A new approach is needed to reduce both the personal suffering and the burden of the illness on social and medical services. To date, there has been little scientific investigation into the development of specific treatment for those patients with chronic AN. This study will trial a recently manualised therapy - non-specific supportive clinical management - which initial evidence suggests may hold promise for chronic AN because it offers a more indirect, motivationally-matched approach. This treatment will be compared to the establishment therapy Cognitive Behavioural Therapy. Patients will be randomly allocated to one of the two treatment conditions and will receive 40 sessions over 12 months. They will be thoroughly assessed prior to during and after they have completed treatment and followed up for 6 months. This is the worlds first trial of a psychological treatment for chronic AN; it is hoped the study will establish an effective treatment for this debilitating and expensive illness. Further, as the project aims to explore the core, but often over-looked, feature of AN - poor motivation for recovery - it will also be in a position to shed light on the deep psychological processes that maintain this illness.Read moreRead less
Rapidly giving intravenous fluid to prevent or treat shock (fluid resuscitation) is one of the commonest treatments given to critically ill patients. Current guidelines recommend crystalloid solutions but it is unknown whether any particular crystalloid is better than others. This trial will determine whether the use of one of two crystalloid fluids, saline or PlasmaLyte, reduces the risk of organ injuries, such as kidney failure, and improves patients chances of surviving critically illness.
Improving mental health nurses’ retention and quality of nursing practice. This project aims to improve mental health nurses’ resilience, retention and quality of practice through implementation of a resilience-building program. There is a critical national shortage of nurses in mental health, and attrition of the mental health nursing workforce is due in large part to workplace stressors. As a world-first in the field, the study will compare outcomes for mental health nurses who participate in ....Improving mental health nurses’ retention and quality of nursing practice. This project aims to improve mental health nurses’ resilience, retention and quality of practice through implementation of a resilience-building program. There is a critical national shortage of nurses in mental health, and attrition of the mental health nursing workforce is due in large part to workplace stressors. As a world-first in the field, the study will compare outcomes for mental health nurses who participate in the resilience program with a group of nurses who do not. Extending on a successful pilot, we expect the outcomes to be improved nurse resilience, turnover intention, and quality of nursing practice, and reduced negative psychological impacts of workplace stress. Read moreRead less
A critical psychological investigation of nurses' experiences, understandings and perceptions of nursing eating disordered patients. This innovative project will investigate the experiences, understandings and perceptions of nurses working with eating disordered patients in hospital contexts. Nurses currently nursing eating disordered patients will be interviewed in depth using a semi-structured interview schedule. Interviews will be audio-recorded and transcribed verbatum. The interview transcr ....A critical psychological investigation of nurses' experiences, understandings and perceptions of nursing eating disordered patients. This innovative project will investigate the experiences, understandings and perceptions of nurses working with eating disordered patients in hospital contexts. Nurses currently nursing eating disordered patients will be interviewed in depth using a semi-structured interview schedule. Interviews will be audio-recorded and transcribed verbatum. The interview transcripts will then be systematically analysed using a qualitative discourse analytic methodology. The aim will be to identify the specific discursive resources that nurses use to frame and make sense of their experiences, understandings and perceptions of nursing eating disordered patients. The project has clinical and social scientific significance, and will contribute to improved treatment outcomes.Read moreRead less
Creating effective employment solutions for youth with psychosis. Young people with severe mental illness face the general difficulty of finding paid work, and the specific difficulty of finding employment which can accommodate their health needs. Without early intervention, and access to supported employment, health and rehabilitation services, these young Australians face long-term welfare dependency. This Project will identify leading international models that provide supported employment for ....Creating effective employment solutions for youth with psychosis. Young people with severe mental illness face the general difficulty of finding paid work, and the specific difficulty of finding employment which can accommodate their health needs. Without early intervention, and access to supported employment, health and rehabilitation services, these young Australians face long-term welfare dependency. This Project will identify leading international models that provide supported employment for young people with psychosis and examine why such effective and integrated support models have not been implemented domestically. The Project will then develop a detailed policy and funding framework to facilitate the adoption or adaptation of international best practice in Australia.Read moreRead less
Emotion Regulation in Posttraumatic Stress Disorder. Posttraumatic Stress Disorder (PTSD) can affect 7-12% of Australians in their lifetime. It is a chronic disorder with enormous personal, social and economic costs. In the current climate of increasing mass violence and natural disaster, the health burden of PTSD is expected to rise. This project will help us identify core processes and mechanisms involved in PTSD, and help us to develop more effective and specialized treatments. It will al ....Emotion Regulation in Posttraumatic Stress Disorder. Posttraumatic Stress Disorder (PTSD) can affect 7-12% of Australians in their lifetime. It is a chronic disorder with enormous personal, social and economic costs. In the current climate of increasing mass violence and natural disaster, the health burden of PTSD is expected to rise. This project will help us identify core processes and mechanisms involved in PTSD, and help us to develop more effective and specialized treatments. It will also extend our understanding of how the brain inhibits emotion, which has wider relevance for many anxiety disorders in terms of their development and prevention.Read moreRead less