Discovery Early Career Researcher Award - Grant ID: DE230100693
Funder
Australian Research Council
Funding Amount
$457,350.00
Summary
Emergence: Examining gender equity in music via a new contemporary opera. This DECRA will investigate one of Australia’s significant art-forms: opera. Led by an established Australian composer, it aims to develop new technologies and methods for composition and collaboration. The expected outcomes include new analysis of contemporary, international operatic practice and an original Australian opera that focuses on gender equity in music as its subject, translating data on this topic into creativ ....Emergence: Examining gender equity in music via a new contemporary opera. This DECRA will investigate one of Australia’s significant art-forms: opera. Led by an established Australian composer, it aims to develop new technologies and methods for composition and collaboration. The expected outcomes include new analysis of contemporary, international operatic practice and an original Australian opera that focuses on gender equity in music as its subject, translating data on this topic into creative-practice. The DECRA's significance is to create new, more inclusive frameworks for opera that centre women and gender-diverse music creators and can extend to other musical genres. Benefits include the investigation of urgent issues arising now in Australian workplaces and amplification of the voices of the marginalised.Read moreRead less
Southern Ocean aerosols: sources, sinks and impact on cloud properties. This project aims to provide fundamental process-level understanding of atmospheric aerosol processes over the Southern Ocean, a region that has a profound influence on the Australian and global climate and where climate models perform poorly. Comprehensive observations during 3 Southern Ocean voyages and land-based measurements will enhance our knowledge of aerosols and cloud formation in that region and provide much-needed ....Southern Ocean aerosols: sources, sinks and impact on cloud properties. This project aims to provide fundamental process-level understanding of atmospheric aerosol processes over the Southern Ocean, a region that has a profound influence on the Australian and global climate and where climate models perform poorly. Comprehensive observations during 3 Southern Ocean voyages and land-based measurements will enhance our knowledge of aerosols and cloud formation in that region and provide much-needed data for improving global climate models. Expected outcomes include more accurate seasonal and latitudinal representations of Southern Ocean aerosol populations, properties and sources. The main benefit includes improvements in weather forecasting and future climate projection for Australia and the Southern Hemisphere.Read moreRead less
Improving Weight Loss By Intermittent Use Of Very Low Energy Diet: The TANGO Diet Trial (Temporary Phases Of Accelerated Weight Loss For Noticeably Greater Outcomes)
Funder
National Health and Medical Research Council
Funding Amount
$660,736.00
Summary
Very low energy diet (VLED) is being increasingly used for the treatment of obesity, but the resultant weight loss is usually transient, partly because it induces powerful adaptive responses that inhibit weight loss and promote regain. We have shown that 'taking a break from dieting' for 2 weeks reduces these adaptive responses. In this project we will thus test whether weight loss outcomes with VLED can be improved via intermittent use, where periods on the VLED are alternated with 'breaks'.
Effects Of Fast Versus Slow Weight Loss On Fat, Muscle And Bone In Postmenopausal Women
Funder
National Health and Medical Research Council
Funding Amount
$316,450.00
Summary
Very low energy diets (VLED) are increasingly used to treat obesity. Of concern is the fact that VLED induce adaptive responses that can inhibit loss of, and promote regain of, abdominal fat while decreasing lean body mass, muscle strength and bone density. This project will therefore determine whether VLEDs could have negative effects on body composition that increase the risk of metabolic disease, sarcopenia or osteoporosis, and if so, what mechanisms are involved.
This proposal is designed to test the protein leverage hypothesis (PLH) in humans: the idea that the level of food consumption in humans, like other animals, is adjusted to maintain a target protein intake. As the prevalence of overweight and obesity increases, with its attendant health problems, the need to identify which dietary components limit rather than exacerbate energy intake is imperative. According to the PLH, the consumption of a diet low in % protein and high in % fat and carbohydrat ....This proposal is designed to test the protein leverage hypothesis (PLH) in humans: the idea that the level of food consumption in humans, like other animals, is adjusted to maintain a target protein intake. As the prevalence of overweight and obesity increases, with its attendant health problems, the need to identify which dietary components limit rather than exacerbate energy intake is imperative. According to the PLH, the consumption of a diet low in % protein and high in % fat and carbohydrate, typical of many Western countries, inevitably requires the ingestion of additional energy to maintain protein intake constant, thus driving weight gain. Conversely, the consumption of a diet that is relatively high in % protein requires the ingestion of lower levels of energy, creating the potential for weight loss. Preliminary experimental and population-level nutritional survey data support the PLH, as does the finding that protein is more satiating than other macronutrients. If, as predicted, small changes in the proportion of protein in diets described in the current study are found to impact on total energy intake there will be significant implications for weight control strategies. Thus, if the PLH is confirmed, public health dietary recommendations and government policy settings for the food industry will need to change. Large-scale intervention studies aimed at demonstrating the longer term impact on body weight will also be required.Read moreRead less
Atmospheric composition and climate change. Changing composition and distribution of atmospheric trace gases and aerosols are the driving forces behind changes in climate and the environment at the earth's surface. This proposal is to undertake a program of ground based infrared remote sensing measurements as part of the Network for Detection of Stratospheric Change to investigate some of the most relevant atmospheric processes and species central to the greenhouse effect and ozone depletion. S ....Atmospheric composition and climate change. Changing composition and distribution of atmospheric trace gases and aerosols are the driving forces behind changes in climate and the environment at the earth's surface. This proposal is to undertake a program of ground based infrared remote sensing measurements as part of the Network for Detection of Stratospheric Change to investigate some of the most relevant atmospheric processes and species central to the greenhouse effect and ozone depletion. State-of-the-art measurements, advances in analysis techniques, and the measurement of isotopic fractionation will all contribute to advances in capabilities. Validation of satellite-based remote sensing instruments is also an important facet of the work.Read moreRead less
The Molecular Mechanism Of Ion-coupled Transport In The Brain
Funder
National Health and Medical Research Council
Funding Amount
$441,407.00
Summary
Cells in the brain communicate through chemical signals called neurotransmitters. Neurotransmitter transporters reside in the membranes of cells and are responsible for regulating levels of these chemicals in the brain. They play an important role in the normal function of the human brain but their dysfunction is responsible for many diseases including Alzheimer's disease and motor neuron disease. It is crucial to understand how these proteins work in both normal and disease states.
Better greenhouse gas budgets: new techniques and applications. The most recent (2001) international assessment strongly confirms the link between global climate change and human-induced changes in atmospheric composition. However, improved knowledge of atmospheric trace gas budgets is essential for better modelling of future climate change and formulation of public policy. We have developed novel techniques for atmospheric trace gas and isoptic analysis that provide new tools for resolving trac ....Better greenhouse gas budgets: new techniques and applications. The most recent (2001) international assessment strongly confirms the link between global climate change and human-induced changes in atmospheric composition. However, improved knowledge of atmospheric trace gas budgets is essential for better modelling of future climate change and formulation of public policy. We have developed novel techniques for atmospheric trace gas and isoptic analysis that provide new tools for resolving trace gas budgets in ways not previously possible. We will apply these tools to improve our understanding of the Australian and global budgets of greenhouse gases, especially nitrous oxide and methane, for which sources still have unacceptably large uncertainties.Read moreRead less
Innovative measurement and modelling of greenhouse fluxes at regional scales across Australia. Carbon dioxide accounts for around 60% of the enhanced greenhouse effect. This proposal aims to markedly improve knowledge of the exchange of carbon, mostly as CO2, between atmospheric, ocean and land-based reservoirs in the Australian region. This will be achieved through a suite of measurements using innovative technologies: satellite and ground based remote sensing as well in situ measurements at ....Innovative measurement and modelling of greenhouse fluxes at regional scales across Australia. Carbon dioxide accounts for around 60% of the enhanced greenhouse effect. This proposal aims to markedly improve knowledge of the exchange of carbon, mostly as CO2, between atmospheric, ocean and land-based reservoirs in the Australian region. This will be achieved through a suite of measurements using innovative technologies: satellite and ground based remote sensing as well in situ measurements at Darwin and on the Ghan railway from Darwin to Adelaide. The measurements will be used to constrain inverse models of the carbon cycle and significantly reduce uncertainties in regional carbon source estimates. These estimates will in turn be compared to the Australian National Greenhouse Gas Inventory for comparison and verification.Read moreRead less