Development of a new diet to improve insulin sensitivity and manage weight in healthy cats. This project will determine if a low carbohydrate, moderate fat, high protein diet improves insulin sensitivity and reduces weight gain in cats compared to a typical high-carbohydrate grocery line diet. It will identify risk factors for weight gain such as increased fasting insulin concentration and will also determine which simple assessment of insulin sensitivity best correlates with insulin sensitivity ....Development of a new diet to improve insulin sensitivity and manage weight in healthy cats. This project will determine if a low carbohydrate, moderate fat, high protein diet improves insulin sensitivity and reduces weight gain in cats compared to a typical high-carbohydrate grocery line diet. It will identify risk factors for weight gain such as increased fasting insulin concentration and will also determine which simple assessment of insulin sensitivity best correlates with insulin sensitivity measured by a gold standard. This project should lead to the formulation of a diet designed to improve insulin sensitivity and minimize weight gain in cats, and allow for earlier identification of cats at risk of obesity.Read moreRead less
Development of a non-invasive diagnostic test of Embryo Viability. A successful outcome will:
. improve the cost effectiveness of assisted reproductive technologies resulting in reduced health care costs and allowing greater use of ART in animal production
. by greater cost-effectiveness, facilitate greater access to these advanced technologies in less well developed economies
. build the national capacity in development and validation of biotech diagnostics
. build collaborative relationsh ....Development of a non-invasive diagnostic test of Embryo Viability. A successful outcome will:
. improve the cost effectiveness of assisted reproductive technologies resulting in reduced health care costs and allowing greater use of ART in animal production
. by greater cost-effectiveness, facilitate greater access to these advanced technologies in less well developed economies
. build the national capacity in development and validation of biotech diagnostics
. build collaborative relationship between the CI, University of Sydney and a leading industry partner (Cook Australia)
. lead to significant new fundamental knowledge in embryology that will be of major International significance
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Pathophysiological mechanisms in equine dyschondroplasia (osteochondrosis). Dyschondroplasia (osteochondrosis) is a developmental orthopaedic disease of horses, which causes significant wastage within the Thoroughbred racing industry. The disease affects growth cartilage beneath joint surfaces in such a way that cartilage fails to be replaced by bone, resulting in defects in the joint surface and lameness. This project will identify differences in gene expression between normal cartilage and ea ....Pathophysiological mechanisms in equine dyschondroplasia (osteochondrosis). Dyschondroplasia (osteochondrosis) is a developmental orthopaedic disease of horses, which causes significant wastage within the Thoroughbred racing industry. The disease affects growth cartilage beneath joint surfaces in such a way that cartilage fails to be replaced by bone, resulting in defects in the joint surface and lameness. This project will identify differences in gene expression between normal cartilage and early dyschondroplastic lesions, in order to identify the sequence of molecular events leading to induction of disease. The basic understanding of joint development obtained from this work will assist in the development of strategies to prevent and diagnose dyschondroplasia in horses.Read moreRead less
Biomarkers and objective assessment of cognitive and brain effects of fish oil dietary supplementation. There are potential widespread community benefits from knowing whether consuming fish oils will improve cognitive function. This is mainfest in children and even more so in those suffering attention deficits at a time when inattention and hyperacitvity is likely to permanently lower their overall career prospects.