How do vortices live in spatio-temporally complex flows? The project aims to understand the fundamental mechanism of vortices occurring in flows involving spatio-temporal complexity, by using the combination of dynamical systems theory and asymptotic analysis. This innovative combined mathematical analysis will be coupled with sophisticated computations to be enabled by the international interdisciplinary collaboration between the Mathematics and Engineering at Australia and Japan. The expected ....How do vortices live in spatio-temporally complex flows? The project aims to understand the fundamental mechanism of vortices occurring in flows involving spatio-temporal complexity, by using the combination of dynamical systems theory and asymptotic analysis. This innovative combined mathematical analysis will be coupled with sophisticated computations to be enabled by the international interdisciplinary collaboration between the Mathematics and Engineering at Australia and Japan. The expected outcomes are breakthroughs in the fundamental understanding of turbulence. This should lead to significant insight into better turbulent modellings used in, for example, wide range of engineering, physiological and geophysical flows.Read moreRead less
Reducing rocket resonance is the key to safer spaceflight. This fellowship considers a particularly dangerous component of rocket launch, which is the potential for destructive feedback loops to form either in the nozzle, or between the nozzle and the launch pad. CI Edgington-Mitchell is a world leader in the study of resonance in jet engines, having developed best-in-field methodologies for the problem. In this innovative fellowship, he will apply these methodologies to better understand the da ....Reducing rocket resonance is the key to safer spaceflight. This fellowship considers a particularly dangerous component of rocket launch, which is the potential for destructive feedback loops to form either in the nozzle, or between the nozzle and the launch pad. CI Edgington-Mitchell is a world leader in the study of resonance in jet engines, having developed best-in-field methodologies for the problem. In this innovative fellowship, he will apply these methodologies to better understand the dangerous resonances that can occur during rocket launch, using a combination of experimental, numerical, and theoretical techniques, in partnership with NASA, Stanford, and the CNRS.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100400
Funder
Australian Research Council
Funding Amount
$425,963.00
Summary
Fallopian tube on-a-chip for understanding mammalian reproduction. This project aims to reveal the fundamental physics and biology of mammalian reproduction by engineering the first comprehensive 3D culture model of the fallopian tube. The project expects to generate significant new knowledge about the exact role of the fallopian tube anatomy and physiology on the formation and function of epithelial tissue, using innovative approaches to simultaneously measure the full dynamics of epithelial ce ....Fallopian tube on-a-chip for understanding mammalian reproduction. This project aims to reveal the fundamental physics and biology of mammalian reproduction by engineering the first comprehensive 3D culture model of the fallopian tube. The project expects to generate significant new knowledge about the exact role of the fallopian tube anatomy and physiology on the formation and function of epithelial tissue, using innovative approaches to simultaneously measure the full dynamics of epithelial cell activity and sperm motion. The expected outcome of the project is to reveal the cooperative role of sperm, egg and epithelial tissue on fertilisation. This should provide significant benefits, such as important biophysical insights into mammalian reproduction and new research tools to replace animal models.Read moreRead less
Impact of roughness on adverse pressure gradient turbulent boundary layers. This project aims to develop a novel technique for measuring time-resolved fluid velocity vector fields in high-speed flows to investigate rough wall turbulence in adverse pressure gradient environments in unprecedented detail. By using this innovative instrument to study these widespread but poorly understood turbulent flows in power generation and transport, the project seeks to generate new knowledge. Expected outcome ....Impact of roughness on adverse pressure gradient turbulent boundary layers. This project aims to develop a novel technique for measuring time-resolved fluid velocity vector fields in high-speed flows to investigate rough wall turbulence in adverse pressure gradient environments in unprecedented detail. By using this innovative instrument to study these widespread but poorly understood turbulent flows in power generation and transport, the project seeks to generate new knowledge. Expected outcomes include the development of a new instrument and fundamental knowledge leading to improved designs with higher efficiencies in power generation and transport, resulting in significant benefits such as increased energy security, reduced greenhouse gas emissions, and improved quality of life for individuals and society.Read moreRead less
An adaptive surface for improved modelling of rough wall bounded turbulence. This project aims to improve the prediction of drag where fluid flows over rough surfaces. This is a significant problem, with the uncertainty in drag penalty prediction for shipping alone exceeding ten billion dollars annually. The societal importance of these flows demands action, yet novel approaches must be sought to efficiently explore the wide range of roughness types encountered in practice. An adaptive surface i ....An adaptive surface for improved modelling of rough wall bounded turbulence. This project aims to improve the prediction of drag where fluid flows over rough surfaces. This is a significant problem, with the uncertainty in drag penalty prediction for shipping alone exceeding ten billion dollars annually. The societal importance of these flows demands action, yet novel approaches must be sought to efficiently explore the wide range of roughness types encountered in practice. An adaptive surface is proposed, where a roughness configuration can be dialled in at the press of a button, to rapidly converge on improved models. A key outcome of this project will be improved predictive models of drag for rough wall flows. Benefits will include improved efficiencies and reduced emissions across a wide range of industries.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100754
Funder
Australian Research Council
Funding Amount
$426,154.00
Summary
Drag Prediction over Rough Surfaces using Hardware-Accelerated Simulations. This project aims to uncover the relationship between roughness topography and drag by utilising high-performance and efficient hardware acceleration. This project expects to generate new knowledge in the area of rough-wall turbulent boundary layer by using state-of-the-art hardware accelerated high fidelity simulations and machine learning techniques to identify important roughness parameters. Expected outcomes of this ....Drag Prediction over Rough Surfaces using Hardware-Accelerated Simulations. This project aims to uncover the relationship between roughness topography and drag by utilising high-performance and efficient hardware acceleration. This project expects to generate new knowledge in the area of rough-wall turbulent boundary layer by using state-of-the-art hardware accelerated high fidelity simulations and machine learning techniques to identify important roughness parameters. Expected outcomes of this project include the development of a novel, more accurate, and robust model to predict drag. This would lead to improved data-driven policies for more sustainable and profitable airline and maritime industries.Read moreRead less
Microfluidics to explore the uptake of nanoparticles by endothelial cells. This project aims to develop microfluidic technologies for generating lipid nanoparticles with customised properties and investigating their delivery to endothelial cells under various flow dynamics. The project expects to advance our fundamental knowledge of biophysical and biological mechanisms underlying the uptake of lipid nanoparticles by endothelial cells. Expected outcomes of this project include enhanced delivery ....Microfluidics to explore the uptake of nanoparticles by endothelial cells. This project aims to develop microfluidic technologies for generating lipid nanoparticles with customised properties and investigating their delivery to endothelial cells under various flow dynamics. The project expects to advance our fundamental knowledge of biophysical and biological mechanisms underlying the uptake of lipid nanoparticles by endothelial cells. Expected outcomes of this project include enhanced delivery of nanoparticles to vessel walls. This should provide significant benefits, such as establishing a framework for designing future nano delivery systems, which would benefit Australian biotechnology industries.
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On the Combustion of Green Hydrogen in Future Energy Systems. This project aims to address key fundamental issues that will facilitate the combustion of hydrogen-based fuels for power and mobility. This is achieved by applying advanced laser diagnostics and novel computational methods to turbulent flames of hydrogen fuel blends hence generating new physical knowledge and predictive models. These will provide engineers with essential tools to design and operate fuel-flexible energy systems that s ....On the Combustion of Green Hydrogen in Future Energy Systems. This project aims to address key fundamental issues that will facilitate the combustion of hydrogen-based fuels for power and mobility. This is achieved by applying advanced laser diagnostics and novel computational methods to turbulent flames of hydrogen fuel blends hence generating new physical knowledge and predictive models. These will provide engineers with essential tools to design and operate fuel-flexible energy systems that speed up the critical transition towards employing green hydrogen. Expected outcomes include novel experimental methods and databases, reliable software, and graduates capable of facilitating this transition and accelerating the global decarbonization process while positioning Australia as a hydrogen superpower.Read moreRead less
On the Hunt: Boosting Productivity of Cell Factories by Advanced Searches . This project aims to advance our fundamental understanding of molecular mechanisms underlying protein secretion in yeast, an industrial workhorse and a model organism. It will develop a unique multifaceted research platform to identify and analyse superior yeast strains with the desired traits at the single-cell level. Expected outcomes include a new analytical tool for high-throughput strain analysis and advanced knowle ....On the Hunt: Boosting Productivity of Cell Factories by Advanced Searches . This project aims to advance our fundamental understanding of molecular mechanisms underlying protein secretion in yeast, an industrial workhorse and a model organism. It will develop a unique multifaceted research platform to identify and analyse superior yeast strains with the desired traits at the single-cell level. Expected outcomes include a new analytical tool for high-throughput strain analysis and advanced knowledge of yeast molecular biology that can be applied to improve cell factories for the next generation of fuels, food and pharmaceuticals. This will provide significant economic and social benefits by boosting biotech industry growth, facilitating the transition to a sustainable society and improving Australia’s biosecurity.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL230100023
Funder
Australian Research Council
Funding Amount
$3,362,355.00
Summary
Highly efficient microscale liquid handling and bio interfacing. The aim is to establish the exciting new field of micro elastofluidics, enabling the development of a highly competitive, sovereign capability in Australia, utilising flexibility and stretchability for efficient and precise handling of tiny volumes of liquid. The program will fill a critical gap in fundamental knowledge in fluid-structure interactions, leading to the development of wearable and implantable devices. The expected out ....Highly efficient microscale liquid handling and bio interfacing. The aim is to establish the exciting new field of micro elastofluidics, enabling the development of a highly competitive, sovereign capability in Australia, utilising flexibility and stretchability for efficient and precise handling of tiny volumes of liquid. The program will fill a critical gap in fundamental knowledge in fluid-structure interactions, leading to the development of wearable and implantable devices. The expected outcomes include innovative platform technologies for sample storage, handling and unique device-human interfaces with broad applications in health and defence. Expected benefits include enhanced capabilities in medical diagnostics, defence force protection and Australia’s sovereign high-tech manufacturing.Read moreRead less