Optimising Severe Malaria Treatment Using Pharmacokinetic-pharmacodynamic Modeling
Funder
National Health and Medical Research Council
Funding Amount
$218,490.00
Summary
Every year, severe malaria kills up to 800,000 people worldwide. To prevent death, a patient must be treated promptly and effectively. Children and adults vary in terms of their response to a malaria drug, and therefore may require a different dosing regimen. We will perform a rigorous analytical assessment of antimalarial drug concentration and efficacy data to determine dosing regimens. This will improve the treatment of severe malaria, and thereby, reduce malaria-related mortality.
Clostridium Difficile: Assessing The Risks To Australia Of An Emerging Healthcare-related Pathogen
Funder
National Health and Medical Research Council
Funding Amount
$1,180,256.00
Summary
Clostridium difficile is a bacterium that causes inflammation of the large bowel that can lead to surgical removal of the bowel or death. In North America and Europe, an international epidemic strain has caused large outbreaks of severe, fatal disease. In 2009, this strain was identified for the first time in Perth, Australia. We will investigate strains currently present in Brisbane and Perth and risk of outbreaks occurring from imported and local strains.
Does Environmental Change Drive The Spatiotemporal Transmission Dynamics Of Echinococcus Spp. In Ningxia, China?
Funder
National Health and Medical Research Council
Funding Amount
$654,548.00
Summary
Human echinococcosis is a chronic debilitating disease with a death rate that can exceed 90%. In China it is a major public health issue where recent environmental changes are likely to increase transmission rates, thus increasing the disease burden. This project will assess the impact of these environmental changes on the transmission of this disease over space and time, it will predict where new cases will arise, and determine the best methods for sustainable control and then elimination.
Developing A System For Comprehensive Quantitative Evaluation Of Public Health Strategies Against HIV/AIDS In Australia: Assessing The Past, Understanding The Present And Planning For The Future
Funder
National Health and Medical Research Council
Funding Amount
$407,358.00
Summary
The overall goal of this project is to develop and implement a system which will make optimal use of all available data on HIV/AIDS from different sources in Australia, uniquely integrate the data routinely into an innovative evaluation framework which will be developed using best modelling and economic practices, and conduct analyses which will improve the effectiveness and efficiency of Australia’s HIV policy and program response to prevent new infections and plan for clinical care required fo ....The overall goal of this project is to develop and implement a system which will make optimal use of all available data on HIV/AIDS from different sources in Australia, uniquely integrate the data routinely into an innovative evaluation framework which will be developed using best modelling and economic practices, and conduct analyses which will improve the effectiveness and efficiency of Australia’s HIV policy and program response to prevent new infections and plan for clinical care required for people living with HIV.Read moreRead less