T Helper Cytokines In Immunity And Organ-specific Autoimmunity
Funder
National Health and Medical Research Council
Funding Amount
$443,946.00
Summary
The overall goal of these studies is to identify mechanisms underlying the effects of cytokines on T cell-mediated immunity, how defects in these processes can result in organ specific autoimmune disease, and whether exploiting these mechanisms may result in improved therapies for individuals with autoimmune diseases. The proposed aims build on my previous work on interleukin-21 and interleukin-21-producing T helper cells in both immunity and autoimmunity.