The rapid interactions of circulating human blood platelets is critical to prevent bleeding, but can cause thrombotic diseases (heart attack, stroke). These highly regulated interactions involve specific adhesive proteins. Our studies will define factors regulating platelet interactions. Imaging the thrombotic process will quantify platelet function at an unprecedented resolution and we have a panel of new candidate reagents that will be assessed for antithrombotic potential.
Deterioration of structural integrity of ageing ships and marine platforms. Deterioration of structural integrity of ageing ships and marine platforms. This project will research the deterioration of structural integrity and remaining life of marine assets such as ships and offshore energy facilities, by integrating structural response analysis methods with aged-structure assessment techniques. Maritime assets exposed to ocean conditions suffer from time dependent phenomena, which reduce structu ....Deterioration of structural integrity of ageing ships and marine platforms. Deterioration of structural integrity of ageing ships and marine platforms. This project will research the deterioration of structural integrity and remaining life of marine assets such as ships and offshore energy facilities, by integrating structural response analysis methods with aged-structure assessment techniques. Maritime assets exposed to ocean conditions suffer from time dependent phenomena, which reduce structural capability, affect safety and could have catastrophic environmental and economic consequences. Making assets available and affordably safe is a problem for operators. The key to prolonging asset life is in understanding the interrelationships over time between the asset’s structural condition and its use. Anticipated outcomes are superior safety, expected lifetime and economic benefits of maritime assets.Read moreRead less
Ship response under corrosion, fatigue and complex sea-state environments. This project will improve understanding of the gradual deterioration of ships and maritime structures subject to metal corrosion, fatigue and extreme sea-state conditions. Increasingly such understanding is necessary for optimal asset management decisions. These include the potential economic, personnel and other risks involved for ship owners and operators, including the Royal Australian Navy (RAN). The project will use ....Ship response under corrosion, fatigue and complex sea-state environments. This project will improve understanding of the gradual deterioration of ships and maritime structures subject to metal corrosion, fatigue and extreme sea-state conditions. Increasingly such understanding is necessary for optimal asset management decisions. These include the potential economic, personnel and other risks involved for ship owners and operators, including the Royal Australian Navy (RAN). The project will use numerical simulation. It will tackle the Fluid-Structure Interaction problem of ships in waves by integrating Finite Element structural response analysis with cutting-edge Smoothed Particle Hydrodynamics methods. The outcomes will provide new insight into remaining asset life and for exploring optimal maintenance strategiesRead moreRead less
Assessing the determinants and consequences of safety climate in the maritime industry. This project will examine the predictors and outcomes of safety climate in the Australian maritime industry. Findings from this project will be used to improve safety policies, regulations and practices that aim to minimise the number of accidents and incidents in Australian waters.
Life in the Shipping Lane; The Cost of Increasing Disturbance to Whales. This project aims to quantify the increasing risk of ship strike to humpback whales in Moreton Bay, and predict the impact of chronic disturbance to nursing calves. The research builds on pilot findings identifying Moreton Bay as a resting area for migrating humpback whales. Using empirical and modelling approaches, this research responds directly to the Federal Government strategy for mitigating ship strike, which explicit ....Life in the Shipping Lane; The Cost of Increasing Disturbance to Whales. This project aims to quantify the increasing risk of ship strike to humpback whales in Moreton Bay, and predict the impact of chronic disturbance to nursing calves. The research builds on pilot findings identifying Moreton Bay as a resting area for migrating humpback whales. Using empirical and modelling approaches, this research responds directly to the Federal Government strategy for mitigating ship strike, which explicitly flags Moreton Bay as an 'area of concern'. The project has been developed in collaboration with traditional owners and industry, and is expected deliver optimal mitigation measures for the region. Findings further carry implications for similar functional habitats along Australia's humpback whale migratory corridors.Read moreRead less