Improving Arm Function After Stroke Using Task Specific Training
Funder
National Health and Medical Research Council
Funding Amount
$832,597.00
Summary
85% of the 15 million people in the world annually who have a stroke cannot use their arm for basic tasks like eating and toileting. With usual health care services, 60% of stroke survivors still have non-functional arms 6 months after stroke. More effective treatments are needed. Task-specific training may improve arm and hand function more than usual care. We will conduct a multicentre randomised controlled trial to test whether task-specific training is more effective than usual care.
Electronic Portable Health File (PHF) To Promote Quality Of Care And Workflow Through Continuity Of Care
Funder
National Health and Medical Research Council
Funding Amount
$694,745.00
Summary
The medical of older individuals with chronicdiseases and with multiple doctors is complex and burdensome for the patient. We have done work where the patient is given charge of a portable personal health record that he-she can update as needed and care givers update at ofiice visits. The preliminary work is positive. Two types have been investigated, an electronic patient health file (on a data stick) and a wallet size booklet. Both have been found accceptable. The goal of this project is to se ....The medical of older individuals with chronicdiseases and with multiple doctors is complex and burdensome for the patient. We have done work where the patient is given charge of a portable personal health record that he-she can update as needed and care givers update at ofiice visits. The preliminary work is positive. Two types have been investigated, an electronic patient health file (on a data stick) and a wallet size booklet. Both have been found accceptable. The goal of this project is to see if short term acceptability and satisfaction will translate into later improved outcomes such as a reduced rate of hospitalizations.Read moreRead less
Circuit Class Therapy For Rehabilitation Clients. A Pragmatic Randomized Controlled Trial Of Therapy Intensity (CIRCIT).
Funder
National Health and Medical Research Council
Funding Amount
$526,361.00
Summary
Loss of independence is common after stroke, and may lead to reduced quality of life and admission to nursing home care. We will investigate if an increased amount of rehabilitation following stroke leads to improved mobility. Two ways of delivering more intense rehabilitation will be compared with usual care to find out which leads to improved physical mobility, and how they compare economically. This will allow health service providers to optimise services and will benefit people with stroke.
Personally Controlled Electronic Health Records For Young Adults With Communication Disabilities: Charting The Course For Successful Child To Adult Health Service Transition.
Funder
National Health and Medical Research Council
Funding Amount
$400,665.00
Summary
Adolescents and young adults with chronic health conditions and communication disabilities struggle to communicate their health information with service providers. This causes problems in care when moving from child to adult health services. This study will investigate their use of the Personally Controlled Electronic Health Record as a means to support timely and effective information exchange to improve healthcare for these vulnerable young adults.
Increasing Rates Of Organ Donor Registration: An RCT To Determine The Differential Effectiveness Of Electronic And Interpersonal Information Interventions.
Funder
National Health and Medical Research Council
Funding Amount
$240,188.00
Summary
Australia has one of the lowest organ donation rates in the world. One of the key strategies identified to improve organ donation is increasing the number of people registered on the Australian Organ Donation Registry (AODR). This study will compare the effectiveness of two strategies designed to encourage students attending TAFE to register their organ donation intentions with the AODR.
Complete Genomics For Mechanistic Insight And Precision Treatments Of Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$1,149,207.00
Summary
This research project will utilise recent developments in genomic technology to make detailed high-resolution genetic maps of individuals with psychotic illness. Where conventional gene discovery approaches focus on differences at the population level, this project will integrate the variation within individuals to determine the network architecture. This will be used to generate genetic profiles for personalised medicine and provide the basis for treatments that are tailored to individuals.
The Efficacy Of N-acetyl Cysteine As An Adjunctive Treatment For First Episode Psychosis
Funder
National Health and Medical Research Council
Funding Amount
$2,143,069.00
Summary
First episode psychosis may foreshadow devastating, chronic illness. Psychosis follows a staged, progressive pathway. There is evidence to suggest illness progression can be diminished and perhaps even averted if appropriate treatments are given at the early stages of illness. This project will test if N-acetycysteine (NAC) administered to young people who have experienced a first episode of psychosis can help prevent this early psychotic experience from developing into a chronic disorder.
Schizophrenia Under The Genomic Lens: Next Generation Sequencing Of Western Australian Families With Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$991,659.00
Summary
We will perform whole genome sequencing of 376 members of 88 Western Australian families, including 113 individuals with a diagnosis of schizophrenia. We will use the sequence data to conduct a gene-cenric analysis of rare genomic variants likely to contribute to schizophrenia risk in these families.
The Outcomes Of Adolescents And Young Adults Who Experience Hallucinations: A Birth Cohort Study
Funder
National Health and Medical Research Council
Funding Amount
$624,842.00
Summary
A national survey reported that 1 in every 12 Australian adolescents experiences hallucinations. Although hallucinations are relatively common experiences, it remains unclear if hallucinations in adolescence are associated with mental illness, and impairment in social and occupational functioning in later adulthood. This study aims to examine the outcomes at 30 years of age in subjects from an Australian birth cohort study who experienced hallucinations during adolescence and young adulthood.
Voltage Gated Calcium Channels And Vitamin D: Exploring The Convergent Links Between Risk Factors For Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$754,288.00
Summary
Occasionally, the evidence from different scientific approaches aligns and new clues are revealed. This application outlines evidence from (a) risk factor epidemiology (linking low neonatal vitamin D and risk of schizophrenia, (b) clues from genetics that implicate neuronal electrical channels, and (c) and new discoveries that show that vitamin D activates these same neuronal channels. This study will use animal experiments to explore these clues in an integrated research program.