Using Mouse Models To Identify Better Therapies For Acute Leukemia And Myelodysplasia
Funder
National Health and Medical Research Council
Summary
Despite great advances in the understanding of the genes that cause cancers of the blood, cure rates for patients with acute leukemia, or a more indolent form called myelodyspslaia, has not improved significantly over the last 20 years, with the majority of patients dying from resistant or recurrent disease within 5 years. Our research will use mouse models of acute leukemia and myelodysplasia to identify the critical genetic pathways that drive these diseases and to design and test new therapie ....Despite great advances in the understanding of the genes that cause cancers of the blood, cure rates for patients with acute leukemia, or a more indolent form called myelodyspslaia, has not improved significantly over the last 20 years, with the majority of patients dying from resistant or recurrent disease within 5 years. Our research will use mouse models of acute leukemia and myelodysplasia to identify the critical genetic pathways that drive these diseases and to design and test new therapies that can be taken into clinical trials.Read moreRead less