Translating Genetic Determinants Of Glaucoma Into Better Diagnosis And Treatment
Funder
National Health and Medical Research Council
Funding Amount
$9,466,000.00
Summary
Glaucoma is the leading cause of irreversible blindness worldwide. By 2020, it will affect 80 million people, and in Australia over the next decade, the overall cost of glaucoma will reach $4.3 billion per annum. This Program will use genetic advances to personalise treatment. Blindness will be prevented in individuals at highest risk, new ways to treat patients will be developed, and better outcomes for patients will result from less treatment and monitoring of low risk cases.
Young Adult Myopia: Genetic And Environmental Associations
Funder
National Health and Medical Research Council
Funding Amount
$809,271.00
Summary
Myopia affects 80% of school leavers in the cities of East Asia, 45% of Asian Australian school leavers and is probably on the rise in European Australian adolescents. Increased levels of education and lack of time outdoors are known to increase the risk of myopia. We will examine 2,000 young adults to find the genes that interact with these risk factors. In addition to confirming when these risk factors are most important, identifying molecular pathways opens the avenue of new treatments.
Population Outcomes And Cost-effectiveness Of Universal Newborn Hearing Vs Risk Factor Screening At Age 5 Years.
Funder
National Health and Medical Research Council
Funding Amount
$540,423.00
Summary
Universal newborn hearing screening (UNHS) is being widely implemented because it is thought to greatly improve outcomes for children with congenital deafness. However, it is also very costly. Between 2003-5, all New South Wales babies were offered UNHS, while Victorian babies were offered a risk-factor screening and referral program. This two-year 'natural experiment' paves the way for a unique population effectiveness and cost-effectiveness study of UNHS as the children reach 5 years of age.
TELEPHONE COUNSELLING FOR MAINTENANCE OF PHYSICAL ACTIVITY, WEIGHT LOSS And GLYCAEMIC CONTROL IN TYPE 2 DIABETES
Funder
National Health and Medical Research Council
Funding Amount
$1,285,894.00
Summary
Regular exercise, a healthy diet and weight loss are key to managing type 2 diabetes, yet these are major challenges for most people with diabetes. This study will evaluate the impact of a telephone counselling program to assist people with type 2 diabetes to exercise, eat a healthy diet and lose weight, with the goal of helping them to sustain these changes over the long-term. It is expected that these lifestyle changes will also result in improved blood glucose control and quality of life.
Hume's Sceptical Materialism. The early modern period is the decisive period in shaping the modern outlook, but its major figures are not well understood in Australia. This project will enable a broader and more unified understanding of the intellectual movements of the period (showing Hume to be not an intellectual outsider but someone offering a sceptical version of the radical Enlightenment) - and so will enable a better understanding of our intellectual heritage.
Descartes' Ontology of Everyday Life. Australia has a strong international reputation in philosophy and the history of philosophy. This project will contribute to our standing in the international community of scholars and to the teaching of Australian students in the historical origins of contemporary ideas and problems. It will furthermore contribute to the growing recognition of early modern interdisciplinary studies within Australia by drawing on ideas from the history of science, early mode ....Descartes' Ontology of Everyday Life. Australia has a strong international reputation in philosophy and the history of philosophy. This project will contribute to our standing in the international community of scholars and to the teaching of Australian students in the historical origins of contemporary ideas and problems. It will furthermore contribute to the growing recognition of early modern interdisciplinary studies within Australia by drawing on ideas from the history of science, early modern philosophy, medieval philosophy and the history of early modern thought and ideas.Read moreRead less
An intellectual history of theoretical innovation in the Anglo-American Humanities. This project makes an important contribution to the debate over humanities education. Post-structuralist theory in the humanities is attacked by some as modish and lacking in values, and defended by others as supporting critical reflection and progressive political and ethical values. The project explores the degree to which the 'moment of theory' represents the return of earlier European university metaphysics t ....An intellectual history of theoretical innovation in the Anglo-American Humanities. This project makes an important contribution to the debate over humanities education. Post-structuralist theory in the humanities is attacked by some as modish and lacking in values, and defended by others as supporting critical reflection and progressive political and ethical values. The project explores the degree to which the 'moment of theory' represents the return of earlier European university metaphysics to the centre of the humanities curriculum. The project will study these shifts in theory in the humanities and show these to be highly relevant to contemporary debates about teaching and learning.Read moreRead less
Philosophy, the Religious Life, and the Making of Modern Science. This project will enhance our understanding of unique features of Western society-in particular the success and prestige of the sciences and the waning influence of religion and philosophy. This will in turn provide fresh insights into science-religion controversies within the West and will shed light on the distinctive nature of the secular ethos of the West in comparison with cultures (such as some Islamic societies) in which r ....Philosophy, the Religious Life, and the Making of Modern Science. This project will enhance our understanding of unique features of Western society-in particular the success and prestige of the sciences and the waning influence of religion and philosophy. This will in turn provide fresh insights into science-religion controversies within the West and will shed light on the distinctive nature of the secular ethos of the West in comparison with cultures (such as some Islamic societies) in which religious considerations play a dominant role in public life and international affairs. Aside from its intrinsic merits, this project will also further promote Australia's growing reputation as a centre for excellence in the field of early modern intellectual history.Read moreRead less
Synthesis and Performance of Novel Polymer Resists for 193 nm Immersion Lithography. The semiconductor industry is one of the largest world-wide, with annual revenue of $217B and employing over 1.5M people around the world. This project provides a unique opportunity for development within Australia of significant expertise in the field of polymers for short-wavelength lithography. The materials to be developed are expected to provide the basis of future genertions of microchips. In addition the ....Synthesis and Performance of Novel Polymer Resists for 193 nm Immersion Lithography. The semiconductor industry is one of the largest world-wide, with annual revenue of $217B and employing over 1.5M people around the world. This project provides a unique opportunity for development within Australia of significant expertise in the field of polymers for short-wavelength lithography. The materials to be developed are expected to provide the basis of future genertions of microchips. In addition the materials have applications in other technologies which are manufactured in Australia, for example in spectactle lenses and optical fibres. A major outcome of this project will be establishment of Australia as a world-leader in this rapidly expanding field.Read moreRead less
Design of novel nanoporous semiconductor materials for clean environment and energy. This project will develop a low cost nanoporous semiconductor device for the capture and conversion of CO2 into fuels by using water and sunlight. This novel approach will deliver a low cost technology that offers clean energy and will help to mitigate global warming.