Efficacious Targeting Of Therapeutic Stem Cells To Diseased Livers
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
This project focuses on the challenging area of effective and optimal dosing of stem cell-based therapy for liver diseases. I will investigate the fate and therapeutic effects of natural, surface-modified stem cells and cell-derived vesicles in the body and in liver regions using mathematical models. My key goal is advance cell therapy by providing better dosing and cell engineering strategies.
Physiologically-based Pharmacokinetics And Pharmacodynamics Of Therapeutic Stem Cells For Liver Disease
Funder
National Health and Medical Research Council
Funding Amount
$848,710.00
Summary
This project focuses on the challenging area of effective and optimal dosing cell-based therapy for liver diseases. We will investigate the fate and therapeutic effects of natural, modified and artificial therapeutic cells in the body and in liver regions using a physiologically-based kinetic model. Our key goal is advance cell therapy by providing a better understanding and dosing guidelines.