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The Influence Of Transcatheter Aortic Valve Implantation On Myocardial Structure And Function
Funder
National Health and Medical Research Council
Funding Amount
$110,218.00
Summary
Transcatheter aortic valve implantation has given options to elderly patients who were previously faced with an open-heart operation. Our research utilises CT scans to determine the anatomical and physiological effects this new technology has on the heart. This research will help to guide the ongoing development and refinement of this technology. The research has the potential to revolutionise how aortic stenosis is assessed and timing of intervention is determined.
Validation Of Point Of CarE CT DeRived FracTionAl Flow Reserve In Stable Coronary Artery Disease (VERITAS)
Funder
National Health and Medical Research Council
Funding Amount
$78,554.00
Summary
In stable coronary artery disease outcomes are dependent on the presence and burden of ischaemia. Current methods of assessing ischaemia are either invasive with associated risks or non-invasive but limited in their diagnostic accuracy. Our research plans to assess the real world feasibility of a novel, non-invasive, point of care CT-Derived Fractional Flow Reserve technique and its potential for guiding clinical decision making and influencing downstream testing.
How Does Fampridine Affect Upper Limb Function In Multiple Sclerosis?
Funder
National Health and Medical Research Council
Funding Amount
$113,237.00
Summary
Multiple sclerosis (MS) is a common and disabling neurological disease affecting thousands of young Australians. In 2011 Fampridine received TGA approval for walking impairment in MS, but its mechanism of action is unknown and its effects on domains other than lower limb function remain untested. Our study will test whether Fampridine improves upper limb impairment in MS patients and will use electrophysiological measures of central nervous system conduction to uncover its mechanism of action.