How Do Anaesthetics Work? A Rational Basis For Safer General Anaesthesia.
Funder
National Health and Medical Research Council
Funding Amount
$592,008.00
Summary
General anaesthetics are a mainstay of modern medicine, but have a small safety margin, requiring skilled anaesthetists for their safe use. There is growing evidence that general anaesthetic exposure may have long-term effects on brain function in both newborns and the elderly. This project will provide a detailed molecular description of anaesthetic action and specificity. It will provide the basis for designing new anaesthetics that are safer, both immediately and for long-term brain function.