Discovery Early Career Researcher Award - Grant ID: DE210100508
Funder
Australian Research Council
Funding Amount
$462,948.00
Summary
How predictions affect visual processing across the cortical hierarchy . Unlike traditional theories of visual perception, recent evidence suggests what a person expects can fundamentally change how they see the world. However, the neuronal mechanisms which would allow expectation to affect perception are poorly understood. This project will use revolutionary recording techniques to determine how multiple brain regions interact to use predictions about the future to change visual processing. The ....How predictions affect visual processing across the cortical hierarchy . Unlike traditional theories of visual perception, recent evidence suggests what a person expects can fundamentally change how they see the world. However, the neuronal mechanisms which would allow expectation to affect perception are poorly understood. This project will use revolutionary recording techniques to determine how multiple brain regions interact to use predictions about the future to change visual processing. The expected outcome is understanding a fundamental theory of brain function for the first time at the level of single neurons. This project will contribute to a new understanding of central theories of how the brain allows us to see which will significantly enhance basic vision science.Read moreRead less
Coding of olfactory information in the piriform cortex. This project aims to understand how electrical activity in the primary olfactory (piriform) cortex enables mice to recognise and remember odours. By using optical recording techniques together with genetic tools, the project expects to generate new knowledge about how the mammalian brain builds internal representations of the external world. Specific outcomes of the project include new insights into the functional architecture of the pirifo ....Coding of olfactory information in the piriform cortex. This project aims to understand how electrical activity in the primary olfactory (piriform) cortex enables mice to recognise and remember odours. By using optical recording techniques together with genetic tools, the project expects to generate new knowledge about how the mammalian brain builds internal representations of the external world. Specific outcomes of the project include new insights into the functional architecture of the piriform cortex and fresh understanding of how olfactory information is encoded and stored in neural circuits. More broadly, the project aims to advance our understanding of how the brain works, with benefits for future improvements in artificial intelligence and brain-machine interfaces.Read moreRead less
How human vision separately determines object and scene motion. This project aims to enhance understanding of how people process visual scenes containing multiple moving objects of interest. The project intends to measure human visual performance to determine how the brain processes multiple motion signals simultaneously. Expected outcomes include an increased understanding of how we are able to use an evolving visual scene to distinguish between changes due to self-motion and those due to the m ....How human vision separately determines object and scene motion. This project aims to enhance understanding of how people process visual scenes containing multiple moving objects of interest. The project intends to measure human visual performance to determine how the brain processes multiple motion signals simultaneously. Expected outcomes include an increased understanding of how we are able to use an evolving visual scene to distinguish between changes due to self-motion and those due to the motion of multiple moving objects such as crowded city footpaths and busy roads. The results will improve our understanding of failures to see moving objects in challenging viewing conditions (for example, high density traffic), and inform work in the design of autonomous driving and augmented reality display systems.Read moreRead less
Gain from pain: new tools from venomous animals for exploring pain pathways. This project aims to explore animal venoms for new pain-causing toxins, to determine their structure and mechanism of action. Many venomous animals use their venom defensively and envenomation is frequently associated with rapid and often excruciating pain. In most cases the molecular mechanisms by which they achieve this is unknown. Using biochemical, pharmacological and biophysical techniques, this project expects to ....Gain from pain: new tools from venomous animals for exploring pain pathways. This project aims to explore animal venoms for new pain-causing toxins, to determine their structure and mechanism of action. Many venomous animals use their venom defensively and envenomation is frequently associated with rapid and often excruciating pain. In most cases the molecular mechanisms by which they achieve this is unknown. Using biochemical, pharmacological and biophysical techniques, this project expects to uncover toxins that employ new mechanisms of pain signalling, leading to new insights into pain physiology.Read moreRead less
The evolution of light detection and its impacts on early vertebrate evolution. The eye is a complex organ crucial for survival. Tracing the evolution of the eye will not only provide basic concepts of how building visual complexity is achieved in nature but also enhance the understanding of the selection pressures driving the radiation of early vertebrates.
Creating new methods to study structure vision. The majority of the structure within natural images is due to third to fifth order correlations between image points. Research has shown that sensitivity to this higher order structure, provides so called Structure Vision. Research has also shown that as few as three to four brain mechanisms are involved, and these may be related to the Minkowski functionals, which in turn are related to the structural and surface properties of real materials. This ....Creating new methods to study structure vision. The majority of the structure within natural images is due to third to fifth order correlations between image points. Research has shown that sensitivity to this higher order structure, provides so called Structure Vision. Research has also shown that as few as three to four brain mechanisms are involved, and these may be related to the Minkowski functionals, which in turn are related to the structural and surface properties of real materials. This project aims to build on recent discoveries of new stimuli to implement objective tests with which to study structure vision with the Partner Organisation. The project aims to also expand on realistic models of how Structure Vision may be computed by just a few coupled cortical pyramidal cells.Read moreRead less
To flee or not to flee: surviving on incomplete information. Even lowly animals, like the Australian fiddler crabs we will be investigating, are surprisingly competent in making the right decisions in complex situations. They actively acquire information and make good use of it to assure their immediate safety and their long term gains. Animals are exquisitely honed by evolution and we would benefit greatly by understanding what makes them so competent: on a theoretical level, we may learn about ....To flee or not to flee: surviving on incomplete information. Even lowly animals, like the Australian fiddler crabs we will be investigating, are surprisingly competent in making the right decisions in complex situations. They actively acquire information and make good use of it to assure their immediate safety and their long term gains. Animals are exquisitely honed by evolution and we would benefit greatly by understanding what makes them so competent: on a theoretical level, we may learn about efficient rules of good decision making and on a practical level, we may be able to design more flexible, robust and clever machines. Besides being useful in this wider context, the results of our research will thus also contribute to a new and 'sophisticated' appreciation of the cognitive design of animal.Read moreRead less
Moving between day and night: Navigational strategies and foraging costs of temporal niche partitioning. This study involves fundamental research to identify the navigational strategies and the foraging cost in animals that occupy different temporal niches. It will make use of the unique research opportunities in Australia, by working with endemic fauna that allows scientists to address questions that would otherwise be hard to answer. The project will introduce the novel technique of differenti ....Moving between day and night: Navigational strategies and foraging costs of temporal niche partitioning. This study involves fundamental research to identify the navigational strategies and the foraging cost in animals that occupy different temporal niches. It will make use of the unique research opportunities in Australia, by working with endemic fauna that allows scientists to address questions that would otherwise be hard to answer. The project will introduce the novel technique of differential GPS to track the paths of ants which has the potential to revolutionise the field of insect navigation. Salience-dependent navigational strategies analysed in this study will be of great interest in the field of engineering and robotics.Read moreRead less
Moving to be seen: a comprehensive analysis of movement-based signal design. Papers on visual motion processing and animal signal design regularly feature in major journals, and the programs of international conferences. We can thus be confident that theoretical advances will attract international attention. We will develop further state-of-the-art methods in motion analysis, with our overall approach likely to serve as a framework for future research programs, although our techniques will have ....Moving to be seen: a comprehensive analysis of movement-based signal design. Papers on visual motion processing and animal signal design regularly feature in major journals, and the programs of international conferences. We can thus be confident that theoretical advances will attract international attention. We will develop further state-of-the-art methods in motion analysis, with our overall approach likely to serve as a framework for future research programs, although our techniques will have applications outside of biology. In addition, we will learn much about the social behaviour of a group of native reptiles about which relatively little is known. Research on the social behaviour of animals is readily comprehended by non-specialists and plays an important role in attracting young people to careers in science.Read moreRead less
The Role Of Corticothalamic Feedback On The Response Dynamics Of Thalamic Neurons
Funder
National Health and Medical Research Council
Funding Amount
$351,852.00
Summary
A fundamental question in neuroscience is how the brain selectively processes sensory information to generate a reliable representation of the world. Positioned in the centre of the brain, the thalamus plays a key role in sensory processing. This project investigates how the interaction between thalamus and cortex shapes the selection and gating of sensory information. This is a fundamental question in basic neuroscience with the potential to increase our knowledge about attentional deficits.