The Characterisation Of The Glycolytic Pathway And TCA Cycle On First And Second Phase Insulin Secretion
Funder
National Health and Medical Research Council
Funding Amount
$85,716.00
Summary
In normal individuals, special cells in the pancreas - beta cells - secrete insulin. Insulin controls blood glucose. However, in diabetes, these beta cells have failed and are unable to perform their function, possibly due to faulty energy production. This project examines the underlying biochemical processes, in particular the energy requirements for insulin secretion. If we can repair this fault, it could identify novel targets for the treatment of diabetes.