Strategies To Enhance Recruitment Of Hematopoietic Stem Cells And Their Differentiation To Retinal Pigment Epithelium
Funder
National Health and Medical Research Council
Funding Amount
$29,627.00
Summary
Age-related macular degeneration (ARMD) is the leading cause of adult blindness in the western world. As the Australian population ages, many more people will suffer from this disease. This project aims to use adult stem cells, called hematopoietic stem cells (HSC) to repair injured vessels in the eye. This approach optimises healthy repair of the retina by facilitating differentiation of HSC into retinal pigment epithelium, the cells whose malfunction is the underlying initiator of the disease.