Targeting Iron Piracy From Host Proteins By Neisseria And Haemophilus Spp. For The Development Of Novel Antimicrobials
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
The bacteria that cause the sexually transmitted infection gonorrhoea and meningococcal disease are a serious health concern. In order to cause disease, these bacteria must obtain the nutrient iron from our bodies. This proposed research will use cutting edge technologies to understand on a molecular level how these bacteria obtain iron during infection. It will then apply this knowledge to develop molecules that prevent these bacteria from obtaining iron, as a means of treating these diseases.
Industrial Transformation Research Hubs - Grant ID: IH230100010
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub for Smart Process Design and Control . ARC Research Hub for Smart Process Design and Control aims to develop and apply advanced computational technologies to model and optimise complex multiphase processes by integrating the novel multiscale and AI modelling approaches. The outcomes include theories, computer models and simulation techniques, advanced knowledge about process modelling and optimisation, innovative technologies and processes for low carbon operations, and tens of ....ARC Research Hub for Smart Process Design and Control . ARC Research Hub for Smart Process Design and Control aims to develop and apply advanced computational technologies to model and optimise complex multiphase processes by integrating the novel multiscale and AI modelling approaches. The outcomes include theories, computer models and simulation techniques, advanced knowledge about process modelling and optimisation, innovative technologies and processes for low carbon operations, and tens of postdoc and PhD students through academic, industrial and international collaboration. Their application will significantly improve energy/process efficiency and reduce CO2 emission. The Hub will generate a significant impact on the mineral and metallurgical industries which are important to Australia.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC220100028
Funder
Australian Research Council
Funding Amount
$4,969,602.00
Summary
ARC Training Centre for Innovative Composites for the Future of Sustainable Mining Equipment. The Centre aims to train industry-focused researchers in advanced manufacturing of new-generation mining equipment and sustainable mining technology, through close collaborations among key universities and mining and manufacturing companies. The Centre will cultivate a team of world-class academic researchers and industry leaders to deliver an innovative program on research of innovative composites coup ....ARC Training Centre for Innovative Composites for the Future of Sustainable Mining Equipment. The Centre aims to train industry-focused researchers in advanced manufacturing of new-generation mining equipment and sustainable mining technology, through close collaborations among key universities and mining and manufacturing companies. The Centre will cultivate a team of world-class academic researchers and industry leaders to deliver an innovative program on research of innovative composites coupled with work-integrated learning, to not only produce a workforce that meets future skills demand but also develop sustainable and cost-effective mining equipment and high-efficiency mining technologies, benefiting the nation's manufacturing and mining sectors and significantly enhancing the competitiveness of the Australian mining industry.Read moreRead less
Model studies of Australian lump ore applied to blast furnace ironmaking. Ore lump use in ironmaking blast furnaces (BFs) requires no preprocessing and has a lower carbon footprint. However, it suffers various technical problems. This project aims to understand and optimize the conditions for such operations. This will be achieved by means of a combined theoretical and experimental program, involving the use of state-of-the-art multiscale computer modelling and simulation techniques. The researc ....Model studies of Australian lump ore applied to blast furnace ironmaking. Ore lump use in ironmaking blast furnaces (BFs) requires no preprocessing and has a lower carbon footprint. However, it suffers various technical problems. This project aims to understand and optimize the conditions for such operations. This will be achieved by means of a combined theoretical and experimental program, involving the use of state-of-the-art multiscale computer modelling and simulation techniques. The research outcomes will be tested in the design and control of lump charging operations in practice through collaboration with the industrial partner. This will ultimately increase Australian ore lump usage in BFs, leading to significant financial and environmental benefits to Australia and the entire steel industry worldwide.Read moreRead less
Thermodynamic basis for ironmaking and slag recycling in circular economy. This project aims to develop new, powerful state-of-the-art computer-based tools to predict the outcomes of complex chemical reactions, high-temperature ironmaking and slag recycling processes. Globally, over 1 billion tonnes of iron are produced each year consuming 30 billion billion (Quintillion) Joules energy! and creating over 300 million tonnes of molten oxides (slags). Our industry partners need new advanced thermod ....Thermodynamic basis for ironmaking and slag recycling in circular economy. This project aims to develop new, powerful state-of-the-art computer-based tools to predict the outcomes of complex chemical reactions, high-temperature ironmaking and slag recycling processes. Globally, over 1 billion tonnes of iron are produced each year consuming 30 billion billion (Quintillion) Joules energy! and creating over 300 million tonnes of molten oxides (slags). Our industry partners need new advanced thermodynamic databases and computer models with which to optimise their major industrial processes and develop new technologies. By delivering these tools, this project expects to benefit both industry and the community through improved process efficiencies, and reductions in energy usage, pollutants, and environmental impacts.
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Mid-Career Industry Fellowships - Grant ID: IM230100157
Funder
Australian Research Council
Funding Amount
$788,572.00
Summary
Improving Australian iron ore comminution for green steel production. Decarbonisation of the iron ore and steel industry will involve the design of new mineral processing approaches to make the Australian iron ore amenable to green steel production. Energy-efficient ore crushing for optimal ore grades production is key to the development and economics of green steel.
This fellowship project, with embedded industry experts, aims at better understanding the fragmentation mechanics of Pilbara iron ....Improving Australian iron ore comminution for green steel production. Decarbonisation of the iron ore and steel industry will involve the design of new mineral processing approaches to make the Australian iron ore amenable to green steel production. Energy-efficient ore crushing for optimal ore grades production is key to the development and economics of green steel.
This fellowship project, with embedded industry experts, aims at better understanding the fragmentation mechanics of Pilbara iron ore. It will exploit micro-computed tomography coupled with advanced mechanical testing to offer transformative characterisation methods of ore comminution. The project outcomes will help develop new technologies and optimal production paths to realise a higher-grade iron ore needed for a decarbonised steel industry.
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Data-driven monitoring of raceway dynamics in ironmaking blast furnaces. Raceway dynamics in ironmaking blast furnaces affect operational stability and cost considerably, yet their dynamic behaviour has not been well monitored online. The project aims to develop a data-driven model for monitoring the internal state of gas-solid-powder reacting flow in the raceway and predicting raceway anomalies online. It will be achieved by combining particle-fluid numerical simulations with data processing an ....Data-driven monitoring of raceway dynamics in ironmaking blast furnaces. Raceway dynamics in ironmaking blast furnaces affect operational stability and cost considerably, yet their dynamic behaviour has not been well monitored online. The project aims to develop a data-driven model for monitoring the internal state of gas-solid-powder reacting flow in the raceway and predicting raceway anomalies online. It will be achieved by combining particle-fluid numerical simulations with data processing and reduced-order state observer, supported by lab/plant experiments, and collaborating with two industry partners from coal and steel industries. The project outcomes including codes, models and raceway control strategies can help promote Australian metallurgical coal's global markets and ultimately the Australian economy.Read moreRead less
Modelling of polydisperse particle-fluid reacting flows. Complex polydisperse particle-fluid reacting flows are widely practised in many industries where particle size distribution is wide and particle number is huge, yet the process design and optimisation are hindered by the lack of fundamental understanding of the complex reacting flows, particularly polydispersity and interactions. The project will tackle this specific challenge by developing a novel particle-scale mathematical model by inco ....Modelling of polydisperse particle-fluid reacting flows. Complex polydisperse particle-fluid reacting flows are widely practised in many industries where particle size distribution is wide and particle number is huge, yet the process design and optimisation are hindered by the lack of fundamental understanding of the complex reacting flows, particularly polydispersity and interactions. The project will tackle this specific challenge by developing a novel particle-scale mathematical model by incorporating new numerical techniques of interphase heat/mass transfers, polydispersity and computation speed-up; and applying it to two typical industry processes for demonstration. The outcomes will be applied across a range of industries of vital importance to Australian economic and technological future.Read moreRead less
Enhanced Fractionation of Mineral Particles According to Density. Aims: -to achieve a significant advance in the hydrodynamic fractionation of particles on the basis of density, and develop an algorithm to deconvolve the fractionation data to produce the underlying density distribution of the particles. Significance: This density distribution, which is used in resource assessment, plant design, and process evaluation in mineral processing, is currently produced using toxic, and environmentally d ....Enhanced Fractionation of Mineral Particles According to Density. Aims: -to achieve a significant advance in the hydrodynamic fractionation of particles on the basis of density, and develop an algorithm to deconvolve the fractionation data to produce the underlying density distribution of the particles. Significance: This density distribution, which is used in resource assessment, plant design, and process evaluation in mineral processing, is currently produced using toxic, and environmentally damaging heavy liquids, despite the emergence of alternative mineral analysers. Expected Outcomes: -a safe, cost effective basis for generating the density distribution. Benefits: -increasing mineral resource recovery through improved access to critical data, while eliminating the need for the toxic heavy liquids.
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Preparation and use of lignite-iron ore composite briquettes for ironmaking. Preparation and use of lignite-iron ore composite briquettes for ironmaking. This project aims to study the briquetting processes of fine powders, and the preparation and utilization of new brown coal (lignite)–iron ore composite briquettes in a blast furnace. Lignite is a low-cost and abundant resource, and could be used in an emerging carbon-iron ore composite briquette for low-cost ironmaking. This project will perfo ....Preparation and use of lignite-iron ore composite briquettes for ironmaking. Preparation and use of lignite-iron ore composite briquettes for ironmaking. This project aims to study the briquetting processes of fine powders, and the preparation and utilization of new brown coal (lignite)–iron ore composite briquettes in a blast furnace. Lignite is a low-cost and abundant resource, and could be used in an emerging carbon-iron ore composite briquette for low-cost ironmaking. This project will perform multi-scale numerical studies, supported by lab/industry-scale experiments, to produce models and control strategies. Anticipated outcomes include better design and control of briquette's preparation and utilization in ironmaking for further cost-cutting; a new market for brown coal; and a more competitive Australian economy.Read moreRead less