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Childhood Diabetes: Translating Evidence Into Practice
Funder
National Health and Medical Research Council
Funding Amount
$444,014.00
Summary
Type 1 diabetes is one of the most common chronic diseases of childhood. The burden of disease on the individual, their family and the community is enormous. The goal of this fellowship is to utilise evidence-based research to inform health policy and enhance the care of young people with diabetes. The proposal addresses patterns of disease in Australia, environmental triggers for diabetes, and care of the young person with diabetes through implementation of national evidence based clinical care ....Type 1 diabetes is one of the most common chronic diseases of childhood. The burden of disease on the individual, their family and the community is enormous. The goal of this fellowship is to utilise evidence-based research to inform health policy and enhance the care of young people with diabetes. The proposal addresses patterns of disease in Australia, environmental triggers for diabetes, and care of the young person with diabetes through implementation of national evidence based clinical care guidelines for type 1 diabetes.Read moreRead less
Childhood Diabetes: Prediction, Prevention And Preservation Of Beta Cells
Funder
National Health and Medical Research Council
Funding Amount
$577,189.00
Summary
Childhood onset type 1 diabetes is a severe life-long disease that has a major impact on the child and their family. While studies have attempted to modify the immune system before or after diagnosis, few clinical trials have recruited young children. The overarching goal of this fellowship is to improve the lives of young people with diabetes, through a multifaceted program of ground-breaking research aimed at prediction, prevention and preservation of insulin producing ?-cells in the pancreas.
Professor Stick is a career clinician researcher in Paediatric Respiratory Medicine. He has established worl-leading research teams focused on respiratory diseases in young children such as cystic fibrosis and asthma. He has has developed innovative methods to study early childhood respiratory diseases and has been responsible for training scores of clinicians and scientists in the field. He has received national and international awards in recognition of his achievements.
Modulation Of Cytokine Responses To Improve Transplant Outcome.
Funder
National Health and Medical Research Council
Funding Amount
$26,186.00
Summary
Bone marrow transplantation remains a mainstay of curative therapy for haematological malignancies. This curative effect is mediated by the transplanted donor immune system which rejects the recipient malignancy. However, the procedure is limited by its serious side effect, known as graft-versus-host disease. This application seeks to better understand these two processes at both an immunological and clinical level with the aim of separating the two so that more patients may be cured of leukaemi ....Bone marrow transplantation remains a mainstay of curative therapy for haematological malignancies. This curative effect is mediated by the transplanted donor immune system which rejects the recipient malignancy. However, the procedure is limited by its serious side effect, known as graft-versus-host disease. This application seeks to better understand these two processes at both an immunological and clinical level with the aim of separating the two so that more patients may be cured of leukaemia.Read moreRead less
HIV infection continues to be a global problem, an effective vaccine is critical to halting its spread. For those infected there is no cure. They require life-long, expensive therapy. The proposed research looks to provide insights that will contribute to the development of an effective vaccine and to clearing the virus from infected patients by using cutting edge laboratory techniques to study patients in populations that are pathogenically informative.