EGF Peptide Signalling Improves Oocyte Maturation And Quality
Funder
National Health and Medical Research Council
Funding Amount
$586,891.00
Summary
Infertility is common and although IVF is widely accepted, the procedure is expensive and is associated with health risks. Using laboratory animals, we have developed significant new insights into mechanisms regulating egg quality. These insights have allowed us to develop a new approach to infertility treatment - crucially, one that eliminates the need for ovarian hormone therapy used in IVF. This project will investigate the basic mechanisms underlying our new approach to enable safe clinical ....Infertility is common and although IVF is widely accepted, the procedure is expensive and is associated with health risks. Using laboratory animals, we have developed significant new insights into mechanisms regulating egg quality. These insights have allowed us to develop a new approach to infertility treatment - crucially, one that eliminates the need for ovarian hormone therapy used in IVF. This project will investigate the basic mechanisms underlying our new approach to enable safe clinical implementation.Read moreRead less
An FMRI Analysis Of The Functional Organization Within The Brain Of Experimental Superficial And Deep Orofacial Pain
Funder
National Health and Medical Research Council
Funding Amount
$307,526.00
Summary
This project will investigate how the human brain processes a number of important aspects of human jaw muscle pain that are clinically relevant but poorly understood. For example, we do not understand why jaw muscle pain has such different behavioural effects to skin pain. Jaw muscle pain is associated with a significant emotional component not seen in with skin pains. Also, skin pain usually has a sharp or burning quality, is well-localized and is readily treated, while jaw muscle pain is a dee ....This project will investigate how the human brain processes a number of important aspects of human jaw muscle pain that are clinically relevant but poorly understood. For example, we do not understand why jaw muscle pain has such different behavioural effects to skin pain. Jaw muscle pain is associated with a significant emotional component not seen in with skin pains. Also, skin pain usually has a sharp or burning quality, is well-localized and is readily treated, while jaw muscle pain is a deep pain that has a dull, aching quality that may be referred to related sites of the face, head and neck. It is also not known why jaw muscle pain is more common in females in comparison to males. Chronic jaw muscle pain is a major symptom of patients with Temporomandibular Disorders, the most common form of non-dental orofacial pain and that involves pain in or about the jaw joint and-or jaw muscles, and often limitation of jaw movement. Chronic jaw muscle pain can have a severe effect on quality of life but its diagnosis and management is difficult. Despite the widespread prevalence of chronic orofacial pains, we have little information on the central processing of chronic human orofacial pain. This proposal will improve our fundamental understanding of how jaw muscle pain is processed in the brain. The way that the central nervous system processes and represents jaw muscle pain will help explain why these pains present differently in the clinic and should provide important information on the differences between females and males in the representation of jaw muscle pain. This information on the central processing of chronic orofacial pain is crucial to inform the direction of novel or specific management strategies. Our long-term goal is to improve the diagnosis and management of patients with Temporomandibular Disorders, and the present application represents a major new direction of research.Read moreRead less
Identifying the goals and strategies people use to make others feel worse. This project aims to identify the goals and strategies people use to make others feel worse, the situation factors affecting goal formation, and the relative impact of different strategies. The project will develop a novel theoretical framework by applying emotion regulation theory a new area (worsening others' emotions), testing predictions through intensive longitudinal methods, experimental studies and a cross-national ....Identifying the goals and strategies people use to make others feel worse. This project aims to identify the goals and strategies people use to make others feel worse, the situation factors affecting goal formation, and the relative impact of different strategies. The project will develop a novel theoretical framework by applying emotion regulation theory a new area (worsening others' emotions), testing predictions through intensive longitudinal methods, experimental studies and a cross-national comparison of 15+ countries. Expected outcomes include new knowledge of the universal psychological processes that underpin aversive interactions, enhanced capacity for international collaboration, and policy guidance. Benefits include the potential to improve programs to decrease workplace bullying and domestic violence.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101223
Funder
Australian Research Council
Funding Amount
$336,318.00
Summary
Using metacognitive self-evaluation to improve knowledge transfer. The knowledge and skills developed in the classroom often do not transfer to the workplace or even to other subjects at school. This project aims to evaluate how the transfer of knowledge can be enhanced by prompting students to evaluate and reflect on their performance in specific ways. The project will identify how different students respond to self-evaluation and how self-evaluation can most effectively be designed and applied ....Using metacognitive self-evaluation to improve knowledge transfer. The knowledge and skills developed in the classroom often do not transfer to the workplace or even to other subjects at school. This project aims to evaluate how the transfer of knowledge can be enhanced by prompting students to evaluate and reflect on their performance in specific ways. The project will identify how different students respond to self-evaluation and how self-evaluation can most effectively be designed and applied in the classroom. Newly developed self-evaluation prompts will be implemented in a computerised and adaptive way so that self-evaluation is tailored to a particular student. This project should provide a scalable and cost-effective way to help students apply what they learn in a more flexible and efficient way. Read moreRead less
Black on White: Indigenous Social Constructions of Race. This project examines the constested meanings of race for Indigenous people in Australia through an analysis of the discourses they deploy in articulating their experiences. By considering their lives as contexts for the reproduction of race the research will offer new knowledge about the ways in which Indigenous people racialise themselves and others. The project has important theoretical and practical implications by elaborating and pr ....Black on White: Indigenous Social Constructions of Race. This project examines the constested meanings of race for Indigenous people in Australia through an analysis of the discourses they deploy in articulating their experiences. By considering their lives as contexts for the reproduction of race the research will offer new knowledge about the ways in which Indigenous people racialise themselves and others. The project has important theoretical and practical implications by elaborating and progressing recent advances in constructions of identity and whiteness. The findings will add new knowledge to the current field of race studies in Australia and abroad. They will be presented in a book and a series of scholarly articles.Read moreRead less
Managing cultural diversity on Australian construction sites. This research will help to improve the dismal occupational health and safety record of the Australian construction industry (240% more injuries than all-industry average). It will also help to reduce the relatively high levels of workplace compensation due to occupational injuries and diseases (70% higher than all-industry average). Since construction employs 8% of the working population and generates 6% of GDP, significant economic a ....Managing cultural diversity on Australian construction sites. This research will help to improve the dismal occupational health and safety record of the Australian construction industry (240% more injuries than all-industry average). It will also help to reduce the relatively high levels of workplace compensation due to occupational injuries and diseases (70% higher than all-industry average). Since construction employs 8% of the working population and generates 6% of GDP, significant economic and social benefits will arise for wider society from a more culturally harmonious, efficient and productive construction industry. Finally, by making construction safer for NESB migrants who are a significant source of labour, this research will help to reduce severe skill shortages.Read moreRead less
Affinities in Multicultural Australia. Concern has grown in Australia and other advanced societies about perceived threats to social cohesion and national identity through diversity. But are people’s values really so different, and are they directly related to ethnicity? This project will provide the first systematic analysis of the affinities (similarities in values and practices) that link diverse groups and individuals in multicultural Australia. It will examine whether such affinities can ou ....Affinities in Multicultural Australia. Concern has grown in Australia and other advanced societies about perceived threats to social cohesion and national identity through diversity. But are people’s values really so different, and are they directly related to ethnicity? This project will provide the first systematic analysis of the affinities (similarities in values and practices) that link diverse groups and individuals in multicultural Australia. It will examine whether such affinities can outweigh differences and provide the basis for local belonging in multi-ethnic neighbourhoods. The Affinities Project turns the current emphasis on difference on its head. It will provide a new knowledge base, crucial to social scientific analysis as well as to policy formation.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130101077
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Recognising the pain of others: gendered displacement, memory and identity in Bosnian refugee diaspora. The project examines the role of gender in forced migration and how violence against Bosnian women during the 1992-95 war has affected their settlement in Australia, Austria and the USA. The outcomes of the project will help guide the formulation of immigration/integration policy in these countries and facilitate better understanding of refugee women in diaspora.
Leadership diversity through relational intersectionality in Australia. This project aims to investigate leadership in contexts characterized by the complex intersection of cultural and gender differences - what is called here ‘relational intersectionality'. The expected outcomes will contribute to the development of new theory on leadership diversity, and a means through which that theory can be leveraged through leadership practice and education. The project will inform methods to better man ....Leadership diversity through relational intersectionality in Australia. This project aims to investigate leadership in contexts characterized by the complex intersection of cultural and gender differences - what is called here ‘relational intersectionality'. The expected outcomes will contribute to the development of new theory on leadership diversity, and a means through which that theory can be leveraged through leadership practice and education. The project will inform methods to better manage the increasing diversity of the Australian workforce and enable improved leadership performance.Read moreRead less
Settlement service literacy among migrants in two states: Victoria and New South Wales. This project aims to assess the level of and need for settlement service literacy (SSL) among newly-arrived migrants. The project will explore and transform understandings of the relationship between migrants’ SSL and cultural integration. This will provide significant benefits, such as producing a theory-driven model to better address migrants’ needs and thus contribute to conceptual advances in theory, res ....Settlement service literacy among migrants in two states: Victoria and New South Wales. This project aims to assess the level of and need for settlement service literacy (SSL) among newly-arrived migrants. The project will explore and transform understandings of the relationship between migrants’ SSL and cultural integration. This will provide significant benefits, such as producing a theory-driven model to better address migrants’ needs and thus contribute to conceptual advances in theory, research and practice in relation to resettlement in Australia.Read moreRead less