Synchrotron developments of new techniques in X-ray interactions with matter, resolving major discrepancies in Quantum Physics and Chemistry. Synchrotron science is a priority area for Australia, the USA, and most first world countries. Development of new ideas and tools for X-ray investigations is the key to future opportunities and is the subject of this proposal. We will develop new techniques for crystallographic electron-density studies, X-ray Anomalous Fine Structure (XAFS) and Multiple-wa ....Synchrotron developments of new techniques in X-ray interactions with matter, resolving major discrepancies in Quantum Physics and Chemistry. Synchrotron science is a priority area for Australia, the USA, and most first world countries. Development of new ideas and tools for X-ray investigations is the key to future opportunities and is the subject of this proposal. We will develop new techniques for crystallographic electron-density studies, X-ray Anomalous Fine Structure (XAFS) and Multiple-wavelength Anomalous Dispersion (MAD), and provide useful advances for X-ray lithography and radiography. Simultaneous investigation of form factors, absorption coefficients, anomalous dispersion and X-ray scattering will provide new experimental tests of relativistic atomic wavefunction calculations, molecular bonding and solid state coupled cluster theory. Major discrepancies will be resolved.Read moreRead less
Development of the PD GeneChip: a research and diagnostic tool for Parkinson's disease. The PD GeneChip will provide both social and economic benefits to Australia. It will be a key research platform for Australian scientists, and will facilitate collaboration both within Australia and overseas. It will assist with health care management of PD (Parkinson's disease) patients by providing a cost-effective diagnostic tool and the possibility of predicting the clinical course of disease. This inform ....Development of the PD GeneChip: a research and diagnostic tool for Parkinson's disease. The PD GeneChip will provide both social and economic benefits to Australia. It will be a key research platform for Australian scientists, and will facilitate collaboration both within Australia and overseas. It will assist with health care management of PD (Parkinson's disease) patients by providing a cost-effective diagnostic tool and the possibility of predicting the clinical course of disease. This information will provide the basis for tailoring treatment to a patients needs. It is anticipated that marketing of the PD GeneChip within Australia and overseas may produce revenue of at least $40 million annually.Read moreRead less
Prediction of outcome following whiplash injury: a multicentre international prospective study. The main aim of this study is to validate a set of biological and psychological prognostic indicators of outcome following whiplash injury that we have previously identified in a single centre prospective cohort. Validation will be in the context of a large multicentre international cohort. This will allow stakeholders involved in whiplash such as health care and insurance providers to predict with co ....Prediction of outcome following whiplash injury: a multicentre international prospective study. The main aim of this study is to validate a set of biological and psychological prognostic indicators of outcome following whiplash injury that we have previously identified in a single centre prospective cohort. Validation will be in the context of a large multicentre international cohort. This will allow stakeholders involved in whiplash such as health care and insurance providers to predict with confidence both those persons at risk of developing chronic symptoms as well as those with a good chance of full recovery. Furthermore the validation of the predictive capacity of these indicators will, for the first time, provide predictive markers that are amenable to specific early multiprofessional treatment interventions.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100217
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
In-Vivo Multispectral and X-ray Micro-CT Imaging: Founding a Western Australian small animal imaging core facility. The Western Australian Small Animal Imaging facility will provide wide access for the West Australian research community to a multimodality functional and dynamic core bioimaging facility to characterise in-vivo animal models, including extensive postgraduate research training. Wide-ranging research outcomes of national and community benefit include imaging tumour development, bone ....In-Vivo Multispectral and X-ray Micro-CT Imaging: Founding a Western Australian small animal imaging core facility. The Western Australian Small Animal Imaging facility will provide wide access for the West Australian research community to a multimodality functional and dynamic core bioimaging facility to characterise in-vivo animal models, including extensive postgraduate research training. Wide-ranging research outcomes of national and community benefit include imaging tumour development, bone metabolism (osteoporosis), neural function (Alzheimer's disease) and regeneration, and infection mechanisms in live animals, which will result in improvements in human health. Imaging and monitoring coral growth, fish age, and soil structure will improve the economics and sustainability of Australia's marine ecosystems and agricultural food production.Read moreRead less