Computational Modeling of RNA Control Networks. One of the most exciting new ideas for understanding the regulation of gene expression involves the contribution of intronic and other non-protein coding RNAs to regulatory networks within cells. This novel role for intronic RNA is currently making headlines within the molecular biology community but has not yet been modelled computationally. The network of genetic regulatory interactions forms a complex system which is amenable to computational ....Computational Modeling of RNA Control Networks. One of the most exciting new ideas for understanding the regulation of gene expression involves the contribution of intronic and other non-protein coding RNAs to regulatory networks within cells. This novel role for intronic RNA is currently making headlines within the molecular biology community but has not yet been modelled computationally. The network of genetic regulatory interactions forms a complex system which is amenable to computational analysis. This project aims to extend current models to incorporate intronic RNA feedback control, complementing parallel studies in vivo, and computationally testing ideas essential to the theoretical understanding of the basis of life.Read moreRead less
Supercomputer Simulation of Hot Fractured Rock Geothermal Reservoir Systems. The project aims to develop an advanced computational model to simulate fractured geomaterials for Hot Fractured Rock (HFR) geothermal energy exploitation in collaboration with Geodynamics Ltd which is developing Australia's first HFR field site. The site has enough stored energy to provide all Australia's energy needs for up to 70 years. The model has the potential to provide the predictive capacity for geothermal ener ....Supercomputer Simulation of Hot Fractured Rock Geothermal Reservoir Systems. The project aims to develop an advanced computational model to simulate fractured geomaterials for Hot Fractured Rock (HFR) geothermal energy exploitation in collaboration with Geodynamics Ltd which is developing Australia's first HFR field site. The site has enough stored energy to provide all Australia's energy needs for up to 70 years. The model has the potential to provide the predictive capacity for geothermal energy extraction required to successfully exploit the immense potential of HFR energy. The expected outcome is a new supercomputer simulation tool to aid in HFR energy facility design, construction, risk assessment and production that will help Australia become a world leader in the emerging worldwide HFR geothermal industry.Read moreRead less
Coding Error Isolation in Computerised Simulation Models with Application to Wastewater Treatment Systems. Simulation code verification through program testing and debugging is crucially important, but is tedious and often difficult. A novel approach will be studied in this project. The approach involves detecting coding errors through back-to-back testing using two independently implemented versions of a given mathematical model, and isolating the coding errors through systematically analysing ....Coding Error Isolation in Computerised Simulation Models with Application to Wastewater Treatment Systems. Simulation code verification through program testing and debugging is crucially important, but is tedious and often difficult. A novel approach will be studied in this project. The approach involves detecting coding errors through back-to-back testing using two independently implemented versions of a given mathematical model, and isolating the coding errors through systematically analysing the test error signal generated (the difference between the outputs of the two models). This is possible because one of the two versions is implemented in such a way that the test error carries an easily identifiable feature. This project could revolutionize the area of model verification.Read moreRead less
ARC Centre for Complex Systems. The Australian Centre for Complex Systems brings together leading researchers from several disciplines and institutions to conduct research on questions fundamental to understanding and managing complex systems. Its core research program, based on the theme of computation in and by networks of agents, has two interwoven strands. The science strand addresses questions about emergent properties, natural computation, and nonlinear dynamics. The engineering strand add ....ARC Centre for Complex Systems. The Australian Centre for Complex Systems brings together leading researchers from several disciplines and institutions to conduct research on questions fundamental to understanding and managing complex systems. Its core research program, based on the theme of computation in and by networks of agents, has two interwoven strands. The science strand addresses questions about emergent properties, natural computation, and nonlinear dynamics. The engineering strand addresses issues about methodology, modelling toolkits, and management and control. Practical applications are advanced via collaborative projects that address key issues in biology, environment, and socio-economics.Read moreRead less
Supercomputer Simulation of Multiscale Dynamic Behaviour in Multiphase Deformable Porous Media. This project will establish and consolidate links between leading groups in China and Australia to develop a new and unique multiscale computational model and algorithm for simulating multiphase nonlinear behaviours of the porous media under dynamic loading conditions, and improve technology transfer between the two groups by the mobility of the ARC International Fellow. This will aid Australian geosc ....Supercomputer Simulation of Multiscale Dynamic Behaviour in Multiphase Deformable Porous Media. This project will establish and consolidate links between leading groups in China and Australia to develop a new and unique multiscale computational model and algorithm for simulating multiphase nonlinear behaviours of the porous media under dynamic loading conditions, and improve technology transfer between the two groups by the mobility of the ARC International Fellow. This will aid Australian geoscience and mining industry, such as in HFR geothermal/UCG energy facility design, construction, risk assessment and production and could help Australia shift away from greenhouse gases and become a world leader in the emerging worldwide HFR geothermal/UCG industry.Read moreRead less
Thinking Systems: Navigating Through Real and Conceptual Spaces. The project will provide fundamental insights into physical and conceptual spaces and develop applications in robotics and information systems. The project brings together national and international researchers to study how humans and other animals navigate: how trajectories through space are used to build maps, the neural bases of these mapping processes and how to use maps to achieve goals. The project will develop a new generati ....Thinking Systems: Navigating Through Real and Conceptual Spaces. The project will provide fundamental insights into physical and conceptual spaces and develop applications in robotics and information systems. The project brings together national and international researchers to study how humans and other animals navigate: how trajectories through space are used to build maps, the neural bases of these mapping processes and how to use maps to achieve goals. The project will develop a new generation of robots that can learn about the physical spaces they work in, and create concept-mapping systems that can map and navigate information spaces. Also, it will provide new insights into the mechanisms regulating human cognition and mental dysfunctions.Read moreRead less
Assessing Oceanic and Tidal Forecast Data For Search and Rescue Purposes. Locating people lost and adrift at sea requires costly resources (aircraft, ships and rescuers) and accurate planning. Rescuers also require estimates of where currents will take them. Australian marine Search and Rescue (SAR) planning uses infrequent (typically once a week) satellite measurements of ocean currents to estimate drift patterns of people at sea. Recently developed ocean forecast models will potentially help ....Assessing Oceanic and Tidal Forecast Data For Search and Rescue Purposes. Locating people lost and adrift at sea requires costly resources (aircraft, ships and rescuers) and accurate planning. Rescuers also require estimates of where currents will take them. Australian marine Search and Rescue (SAR) planning uses infrequent (typically once a week) satellite measurements of ocean currents to estimate drift patterns of people at sea. Recently developed ocean forecast models will potentially help forecast currents between the satellite observations, but are unproven for SAR use at this time and do not include tidal influences. This research project will develop measures of reliability and accuracy of using Ocean Forecasts that include tide forecasts for improving SAR planning outcomes in Australian waters.Read moreRead less