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Molecular Characterisation Of Adiponectin Receptors: Implications For Adiponectin Action And Resistance
Funder
National Health and Medical Research Council
Funding Amount
$95,137.00
Summary
Adiponectin is a hormone secreted by fat cells with anti-inflammatory, anti-atherogenic and insulin sensitising properties. Adiponectin levels and actions are compromised in obesity and type 2 diabetes. Adponectin mediates its effects via two receptors but the mechanisms are poorly understood. This proposal aims to define the underlying mechanisms with the ultimate goal of identifying novel therapeutic strategies to improve adiponectin's actions.
The Effect Of Testosterone Treatment In Men With Type 2 Diabetes And Low Normal Total Testosterone Levels
Funder
National Health and Medical Research Council
Funding Amount
$65,658.00
Summary
This trial will assess the effect of testosterone injections in men with type 2 diabetes and low testosterone levels on control of their diabetes, resistance to insulin and the metabolic syndrome (obesity, high blood pressure, high cholesterol). Results from this trial will clarify if there is a role for testosterone treatment in men with type 2 diabetes.