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Scheme : Development Grants
Research Topic : Injury prevention intervention
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  • Funded Activity

    Targeting Collagen Cross-linking To Improve Scar Appearance

    Funder
    National Health and Medical Research Council
    Funding Amount
    $873,305.00
    Summary
    Scarring is a significant problem after injury, and the life-long appearance of scar can be very detrimental to peoples’ wellbeing, both psychological and physical. This work will develop a new drug to improve scar appearance. The drug is likely to be effective even after scar has formed, making it possible to improve scarring in many people. This will improve the quality of life for people after injury.
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    Funded Activity

    Non-invasive Intra-cranial Pressure Measurement

    Funder
    National Health and Medical Research Council
    Funding Amount
    $639,073.00
    Summary
    This proposal seeks to develop a novel non-invasive method of measuring intra-cranial pressure, an important diagnostic parameter in many form of brain injury or neural disease. It works by quantitative video analysis of the pulsation of the major vein in the eye during induced rises in eye pressure. Many years of study by our group have determined the relationship between vein pulsation pressure and intra-cranial pressure, and this information is used to produce an accurate measurement of intra .... This proposal seeks to develop a novel non-invasive method of measuring intra-cranial pressure, an important diagnostic parameter in many form of brain injury or neural disease. It works by quantitative video analysis of the pulsation of the major vein in the eye during induced rises in eye pressure. Many years of study by our group have determined the relationship between vein pulsation pressure and intra-cranial pressure, and this information is used to produce an accurate measurement of intra-cranial pressure without the need for surgery.
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    Funded Activity

    Application Of Sutureless Technology 'SurgiLux' For Dura Mater Repair: A Proof Of Concept Study

    Funder
    National Health and Medical Research Council
    Funding Amount
    $213,125.00
    Summary
    A unique technology that combines biomaterials and lasers to effectively close and seal wounds could replace sutures in delicate surgery close to the brain. Wound closure in the cranium is still reliant upon sutures or 'stitches' and these have complications; a major one being leakage of cerebro spinal fluid (CSF). The application of 'SurgiLux' technology will both close and seal these wounds quickly and easily, with significant health and economic benefits.
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    Funded Activity

    Developing A Prototype Of A Next Generation Brain Computer Interface

    Funder
    National Health and Medical Research Council
    Funding Amount
    $837,398.00
    Summary
    Persons affected by quadriplegia and hemiplegia from stroke and spinal cord injury have few treatment options. Brain Machine Interfaces reconnect brain to a prosthetic limb, bypassing damaged nervous system. Our group has developed a BMI that can be implanted minimally-invasively, inside a blood vessel in the brain. We propose to manufacture a world-first device for a human clinical trial pilot study. The aim is to restore mechanical control over the physical environment for a paralysed patient.
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    Funded Activity

    Interactive Attention Training Technology To Enhance Cognitive Skills In Early Life

    Funder
    National Health and Medical Research Council
    Funding Amount
    $759,680.00
    Summary
    Over 30,000 Australian children enter school with attention difficulties each year. We have established a suite of tasks to train attention based on over 20 years of research into neurodevelopmental disorders and attention. These are delivered on tablets in the form of a game known as TALI Train. We now aim to show TALI can improve attention in children with acquired brain injuries and typically developing children for commercialisation to a broad market.
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    Funded Activity

    Development Of A Take-home Rehabilitation Device That Improves Visual Stability And Balance In Patients With Peripheral Vestibular Injury

    Funder
    National Health and Medical Research Council
    Funding Amount
    $789,377.00
    Summary
    The balance system senses head motion via the balance organs, one in each inner ear, and stabilises vision during head movements. Without it, every time you walk, run, or drive on a bumpy road, the world appears to bounce. We have developed a device shown to reliably 'train up' the balance system. Our aim is to develop this device further for effective take-home rehabilitation.
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    Funded Activity

    Preclinical Development Of Q2361, A Transforming New Drug For Skin Cancer Prevention In Organ Transplant Recipients

    Funder
    National Health and Medical Research Council
    Funding Amount
    $724,957.00
    Summary
    Patients that receive organ transplants need additional medications in order to prevent organ rejection. Unfortunately, these drugs carry an unwanted side-effect - they permit the development of skin cancer. Currently, other than surgery, little can be done to help these patients. Our preliminary data suggest that a new drug may prevent these skin cancers from forming. This project aims to deliver key insights into the influence of this drug and its role in skin cancer prevention.
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    Funded Activity

    HbA1c Biosensor

    Funder
    National Health and Medical Research Council
    Funding Amount
    $587,164.00
    Summary
    A portable device that can measure glycosylated haemoglobin (HbA1c) in the home will be developed. HbA1c is an important biomarker of the average blood glucose levels over the preceding three months and hence guides a diabetic regarding their blood glucose treatment regime. A 1% decrease in HbA1c levels is associated with a dramatic decrease in chronic health complications from diabetes. The HbA1c meter that will be developed will be able to operate with existing glucose meter technologies.
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    Funded Activity

    Immunotherapy For Childhood Eczema

    Funder
    National Health and Medical Research Council
    Funding Amount
    $965,300.00
    Summary
    The aim of this proposal is to test the safety of a novel immunotherapy based on Helicobacter pylori platform technology to treat childhood allergies. Repeated oral administration of killed H. pylori mimics colonisation in the stomach and assists the development of a balanced immune system without the associated disease risk of live H. pylori. To achieve this goal Professor Barry Marshall has assembled a cross-disciplinary team of experts from Industry, Academia and Clinic.
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    Funded Activity

    Development Of A Blood-based Screening Test For Colorectal Neoplasia; Biomarker Expression In Circulating Tumor Cells And Tumor-derived Microvesicles

    Funder
    National Health and Medical Research Council
    Funding Amount
    $513,938.00
    Summary
    A blood-based test for bowel cancer and the premalignant lesion (i.e. adenomas) has potential to improve several aspects of screening for bowel cancer – improved capacity to detect lesions in well people who do not suspect their presence, avoidance of faecal sampling and fewer false-positive results. There is no reliable simple screening test for adenomas. This study aims at developing a practical blood test based on a device that filters and enriches cells from blood that carry these markers
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    Showing 1-10 of 10 Funded Activites

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